GB1220202A - Pyridine derivatives and intermediates and processes therefor - Google Patents

Pyridine derivatives and intermediates and processes therefor

Info

Publication number
GB1220202A
GB1220202A GB470D GB470D GB1220202A GB 1220202 A GB1220202 A GB 1220202A GB 470 D GB470 D GB 470D GB 470 D GB470 D GB 470D GB 1220202 A GB1220202 A GB 1220202A
Authority
GB
United Kingdom
Prior art keywords
compounds
prepared
pyridine derivatives
novel compounds
feb
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB470D
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Priority claimed from GB665269A external-priority patent/GB1220201A/en
Publication of GB1220202A publication Critical patent/GB1220202A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/82—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

1,220,202. Pyridine derivatives. BEECHAM GROUP Ltd. 7 Feb., 1969 [23 Feb., 1968], No. 4/70. Divided out of 1,220,201. Heading C2C. Novel compounds of Formula I in which R 1 is H or 1-6C alkyl; R 2 is H or an optionally acylated hydrocarbon radical; R 3 is H or an optionally substituted aliphatic or araliphatic radical and X is H, OH, or esterified or etherified OH are prepared from novel compounds II in which R 4 is the residue of an ether group and Y is H, OH or OR 4 by removal of R 4 by known methods. Compounds II are prepared by partial hydrogenation of novel compounds III. Compounds III are prepared by reaction of compounds IV with compounds V in which R<SP>111</SP> 2 is a group selected from R 2 and capable of forming part of a quaternary salt and A 1 - is an anion. The dotted lines in the above formulµ represent a double bond in either the 3 or 4 position of the tetrahydropyridine ring. Intermediates isolated are 2-(p-tolyloxy) tetrahydropyran and 6 - (tetrahydro - 2 - pyranyloxy)- o-cresol prepared from the appropriate phenolic compound and dihydropyran.
GB470D 1968-02-23 1969-02-07 Pyridine derivatives and intermediates and processes therefor Expired GB1220202A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70744868A 1968-02-23 1968-02-23
GB665269A GB1220201A (en) 1968-02-23 1969-02-07 Organic compounds based upon benzoxazocines and intermediates and processes therefor

Publications (1)

Publication Number Publication Date
GB1220202A true GB1220202A (en) 1971-01-20

Family

ID=26240852

Family Applications (1)

Application Number Title Priority Date Filing Date
GB470D Expired GB1220202A (en) 1968-02-23 1969-02-07 Pyridine derivatives and intermediates and processes therefor

Country Status (1)

Country Link
GB (1) GB1220202A (en)

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees