GB1214079A - Heterocyclic-substituted salicylic acids - Google Patents
Heterocyclic-substituted salicylic acidsInfo
- Publication number
- GB1214079A GB1214079A GB46606/68A GB4660668A GB1214079A GB 1214079 A GB1214079 A GB 1214079A GB 46606/68 A GB46606/68 A GB 46606/68A GB 4660668 A GB4660668 A GB 4660668A GB 1214079 A GB1214079 A GB 1214079A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hetero atoms
- salicylic acids
- substituted salicylic
- pyrimidine
- oct
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003870 salicylic acids Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000005842 heteroatom Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- KNLHNDZBUASBQF-UHFFFAOYSA-N 4-pyrimidin-4-ylphenol Chemical compound Oc1ccc(cc1)-c1ccncn1 KNLHNDZBUASBQF-UHFFFAOYSA-N 0.000 abstract 1
- 101100188555 Arabidopsis thaliana OCT6 gene Proteins 0.000 abstract 1
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 abstract 1
- 238000005903 acid hydrolysis reaction Methods 0.000 abstract 1
- 229910000288 alkali metal carbonate Inorganic materials 0.000 abstract 1
- 150000008041 alkali metal carbonates Chemical class 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 239000002221 antipyretic Substances 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 238000006193 diazotization reaction Methods 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 239000003701 inert diluent Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/55—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67327367A | 1967-10-06 | 1967-10-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1214079A true GB1214079A (en) | 1970-12-02 |
Family
ID=24701969
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB46606/68A Expired GB1214079A (en) | 1967-10-06 | 1968-10-01 | Heterocyclic-substituted salicylic acids |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3558641A (enrdf_load_stackoverflow) |
| BR (1) | BR6802728D0 (enrdf_load_stackoverflow) |
| CH (1) | CH502981A (enrdf_load_stackoverflow) |
| DE (1) | DE1801303A1 (enrdf_load_stackoverflow) |
| FR (1) | FR1585315A (enrdf_load_stackoverflow) |
| GB (1) | GB1214079A (enrdf_load_stackoverflow) |
| NL (1) | NL161759C (enrdf_load_stackoverflow) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3993763A (en) * | 1969-03-18 | 1976-11-23 | Ciba-Geigy Corporation | Tertiary aminoacids as anti-inflammatory agents |
| US4001420A (en) * | 1968-12-12 | 1977-01-04 | Science Union Et Cie, Societe Francaise De Recherche Medical | Thiazolyl benzoic acid compounds |
| US3682968A (en) * | 1969-06-25 | 1972-08-08 | Merck & Co Inc | Anti-inflammatory salicylic acid derivatives |
| US3676451A (en) * | 1970-06-09 | 1972-07-11 | Merck & Co Inc | Thiazolylsalicylic acids |
| GB1308028A (en) * | 1970-06-12 | 1973-02-21 | Science Union & Cie | Thiazolylbenzoic acid derivatives and a process for their manufactur |
| US3687971A (en) * | 1970-06-22 | 1972-08-29 | Merck & Co Inc | 4-(pyrrolyl)-salicylic acid derivatives |
| US3929833A (en) * | 1970-10-30 | 1975-12-30 | Sandoz Ag | Organic compounds |
| FR2128285A1 (en) * | 1971-03-11 | 1972-10-20 | Berlin Chemie Veb | Imidazole derivs - with hypotensive mao-inhibitory, anticonvulsant antiinflammatory choleretic and antiviral activity prepn |
| FR2128292A1 (en) * | 1971-03-12 | 1972-10-20 | Berlin Chemie Veb | Imidazole derivs - with hypotensive, mao-inhibitory, anticonvulsant antiinflammatory, choleretic and antiviral activity prepn |
| US3860640A (en) * | 1972-04-12 | 1975-01-14 | Nippon Shinyaku Co Ltd | 3-alkoxy-5-substituted phenylacetic acids |
| US3865839A (en) * | 1973-03-01 | 1975-02-11 | Hoechst Co American | Thiopyranopyrrolylsalicyclic acids and derivatives thereof |
| US4111935A (en) * | 1975-01-02 | 1978-09-05 | Smith Kline & French Laboratories Limited | 3-chloro-6-phenylpyridazine compounds |
| US4152341A (en) * | 1975-12-29 | 1979-05-01 | Imperial Chemical Industries Limited | Triaryl or diarylpyridyl methanes |
| GB1560880A (en) * | 1975-12-29 | 1980-02-13 | Ici Ltd | Diphenylmethane derivatives and pharmaceutical compositions containing them |
| DE2818765A1 (de) * | 1978-04-28 | 1979-11-08 | Basf Ag | Aminoderivate des 2-methyl-5-(2-hydroxystyrol)-1,3,4-thiadiazols |
| EP0195582B1 (en) * | 1985-03-14 | 1990-01-24 | SMITH KLINE DAUELSBERG GmbH | 5-aminosalicylic acid derivatives of non-steroidal antiinflammatory acids |
| GB9204808D0 (en) * | 1992-03-04 | 1992-04-15 | Rhone Poulenc Rorer Ltd | Novel compositions of matter |
| ES2639863B1 (es) * | 2017-03-10 | 2018-09-20 | Universidad De Granada | Compuestos para el tratamiento de enfermedades causadas por la acumulación de oxalato |
-
1967
- 1967-10-06 US US673273A patent/US3558641A/en not_active Expired - Lifetime
-
1968
- 1968-09-24 NL NL6813639.A patent/NL161759C/xx not_active IP Right Cessation
- 1968-09-30 BR BR202728/68A patent/BR6802728D0/pt unknown
- 1968-10-01 GB GB46606/68A patent/GB1214079A/en not_active Expired
- 1968-10-04 FR FR1585315D patent/FR1585315A/fr not_active Expired
- 1968-10-04 DE DE19681801303 patent/DE1801303A1/de active Pending
- 1968-10-07 CH CH1494368A patent/CH502981A/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CH502981A (de) | 1971-02-15 |
| US3558641A (en) | 1971-01-26 |
| FR1585315A (enrdf_load_stackoverflow) | 1970-01-16 |
| BR6802728D0 (pt) | 1973-05-10 |
| DE1801303A1 (de) | 1969-06-19 |
| NL6813639A (enrdf_load_stackoverflow) | 1969-04-09 |
| NL161759B (nl) | 1979-10-15 |
| NL161759C (nl) | 1980-03-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |