GB1208367A - New aryl-sulfonyl ureas, processes for their production and medicaments comprising them - Google Patents
New aryl-sulfonyl ureas, processes for their production and medicaments comprising themInfo
- Publication number
- GB1208367A GB1208367A GB22185/68A GB2218568A GB1208367A GB 1208367 A GB1208367 A GB 1208367A GB 22185/68 A GB22185/68 A GB 22185/68A GB 2218568 A GB2218568 A GB 2218568A GB 1208367 A GB1208367 A GB 1208367A
- Authority
- GB
- United Kingdom
- Prior art keywords
- oxa
- amino
- group
- adamantane
- sulphonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940100389 Sulfonylurea Drugs 0.000 title 1
- 125000004391 aryl sulfonyl group Chemical group 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- ZZLQURFGCICSRP-UHFFFAOYSA-N (2-oxaadamant-1-yl)amine Chemical compound C1C(C2)CC3CC2OC1(N)C3 ZZLQURFGCICSRP-UHFFFAOYSA-N 0.000 abstract 2
- WGQKYBSKWIADBV-UHFFFAOYSA-N benzylamine Chemical compound NCC1=CC=CC=C1 WGQKYBSKWIADBV-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000003993 interaction Effects 0.000 abstract 2
- XRYVAHKDJBBLTN-UHFFFAOYSA-N 1-(4-methylphenyl)sulfonyl-3-(2-oxatricyclo[3.3.1.13,7]decan-1-yl)thiourea Chemical compound C1(=CC=C(C=C1)S(=O)(=O)NC(=S)NC12OC3CC(CC(C1)C3)C2)C XRYVAHKDJBBLTN-UHFFFAOYSA-N 0.000 abstract 1
- YEWFFFAYPIELAC-UHFFFAOYSA-N 2-oxatricyclo[3.3.1.13,7]decan-1-amine hydrochloride Chemical compound Cl.NC12OC3CC(CC(C1)C3)C2 YEWFFFAYPIELAC-UHFFFAOYSA-N 0.000 abstract 1
- LZMPFLUXNFJCAQ-UHFFFAOYSA-N 3-(benzylamino)-2-oxatricyclo[3.3.1.13,7]decan-1-ol Chemical compound C(C1=CC=CC=C1)NC12OC3(CC(CC(C1)C3)C2)O LZMPFLUXNFJCAQ-UHFFFAOYSA-N 0.000 abstract 1
- MCFSCNLXHWWPOD-UHFFFAOYSA-N 4-methyl-n-(sulfanylidenemethylidene)benzenesulfonamide Chemical compound CC1=CC=C(S(=O)(=O)N=C=S)C=C1 MCFSCNLXHWWPOD-UHFFFAOYSA-N 0.000 abstract 1
- PJZZNMUGSKLGBM-UHFFFAOYSA-N Cl.C(C1=CC=CC=C1)NC12OC3CC(CC(C1)C3)C2 Chemical compound Cl.C(C1=CC=CC=C1)NC12OC3CC(CC(C1)C3)C2 PJZZNMUGSKLGBM-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 150000001414 amino alcohols Chemical class 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- 235000013877 carbamide Nutrition 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 230000002218 hypoglycaemic effect Effects 0.000 abstract 1
- 239000012280 lithium aluminium hydride Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- WZHRJGWXUCLILI-UHFFFAOYSA-N sulfonylcarbamic acid Chemical compound OC(=O)N=S(=O)=O WZHRJGWXUCLILI-UHFFFAOYSA-N 0.000 abstract 1
- BUXTXUBQAKIQKS-UHFFFAOYSA-N sulfuryl diisocyanate Chemical compound O=C=NS(=O)(=O)N=C=O BUXTXUBQAKIQKS-UHFFFAOYSA-N 0.000 abstract 1
- 150000003585 thioureas Chemical class 0.000 abstract 1
- 150000003672 ureas Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH679667A CH484098A (de) | 1967-05-12 | 1967-05-12 | Verfahren zur Herstellung von neuen 1-substituierten 3-Arylsulfonylharnstoffen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1208367A true GB1208367A (en) | 1970-10-14 |
Family
ID=4315161
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB22185/68A Expired GB1208367A (en) | 1967-05-12 | 1968-05-10 | New aryl-sulfonyl ureas, processes for their production and medicaments comprising them |
Country Status (9)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4288454A (en) * | 1978-07-24 | 1981-09-08 | Hoffman-La Roche Inc. | Antiviral 1-adamantyl-3-(phenylsulfonyl)thioureas |
-
1967
- 1967-05-12 CH CH1757369A patent/CH490370A/de not_active IP Right Cessation
- 1967-05-12 CH CH679667A patent/CH484098A/de not_active IP Right Cessation
-
1968
- 1968-05-03 NL NL6806328A patent/NL6806328A/xx unknown
- 1968-05-06 US US727043A patent/US3547954A/en not_active Expired - Lifetime
- 1968-05-10 ES ES353768A patent/ES353768A1/es not_active Expired
- 1968-05-10 BE BE714991D patent/BE714991A/xx unknown
- 1968-05-10 IL IL29969A patent/IL29969A0/xx unknown
- 1968-05-10 ES ES353769A patent/ES353769A1/es not_active Expired
- 1968-05-10 GB GB22185/68A patent/GB1208367A/en not_active Expired
- 1968-05-10 AT AT452668A patent/AT281054B/de not_active IP Right Cessation
- 1968-05-13 FR FR1561897D patent/FR1561897A/fr not_active Expired
- 1968-08-08 FR FR162325A patent/FR7788M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AT281054B (de) | 1970-05-11 |
| US3547954A (en) | 1970-12-15 |
| ES353769A1 (es) | 1969-10-16 |
| ES353768A1 (es) | 1969-10-16 |
| CH490370A (de) | 1970-05-15 |
| FR1561897A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1969-03-28 |
| IL29969A0 (en) | 1968-07-25 |
| NL6806328A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1968-11-13 |
| FR7788M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1970-03-31 |
| CH484098A (de) | 1970-01-15 |
| BE714991A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1968-11-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CSNS | Application of which complete specification have been accepted and published, but patent is not sealed |