GB1202377A - A process for the production of substituted phenyl acetic esters - Google Patents
A process for the production of substituted phenyl acetic estersInfo
- Publication number
- GB1202377A GB1202377A GB4570267A GB4570267A GB1202377A GB 1202377 A GB1202377 A GB 1202377A GB 4570267 A GB4570267 A GB 4570267A GB 4570267 A GB4570267 A GB 4570267A GB 1202377 A GB1202377 A GB 1202377A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydrogen
- group
- alkyl
- general formula
- alkyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
Landscapes
- Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1,202,377. o-Anilinophenylacetic acid esters. J. R. GEIGY A.G. 6 Oct., 1967, No. 45702/67. Addition to 1,132,318. Heading C2C. o-Anilinophenylacetic acid esters of the general formula wherein R 1 is a C 1-4 alkyl or C 1-4 alkoxy group, a fluorine, chlorine or bromine atom or the trifluoromethyl group; R 2 is hydrogen or is defined as R 1 ; R 3 is hydrogen, a C 1-4 alkyl or C 1-4 alkoxy group or a fluorine, chlorine or bromine atom; R 4 is hydrogen or a C 1-4 alkyl group; R 5 and R 6 are each hydrogen, a C 1-2 alkyl group or the benzyl group or, when R 6 is hydrogen, R 5 may be a C 1-5 alkyl group; and R 7 is a C 1-6 alkyl group or an aralkyl group having at most 3 carbon atoms in the alkyl moiety, are prepared by reaction of an o-nitrophenylacetic acid ester of the general formula with at least double the molar amount of an aryl magnesium halide of the general formula wherein Hal is a bromine or iodine atom, with the proviso that it has a higher atomic number than every halogen atom bound aromatically in the phenyl radical, and decomposition of the intermediate so formed with saturated ammonium chloride solution.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1451866A CH466256A (en) | 1966-10-07 | 1966-10-07 | Process for the preparation of new substituted phenylacetic acid esters |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1202377A true GB1202377A (en) | 1970-08-19 |
Family
ID=4401499
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB4570267A Expired GB1202377A (en) | 1966-10-07 | 1967-10-06 | A process for the production of substituted phenyl acetic esters |
Country Status (9)
Country | Link |
---|---|
AT (1) | AT276358B (en) |
BE (1) | BE704821A (en) |
CH (1) | CH466256A (en) |
DK (1) | DK120027B (en) |
ES (1) | ES345832A1 (en) |
GB (1) | GB1202377A (en) |
GR (1) | GR37761B (en) |
NL (2) | NL6713631A (en) |
NO (1) | NO121048B (en) |
-
0
- NL NL133741D patent/NL133741C/xx active
-
1966
- 1966-10-07 CH CH1451866A patent/CH466256A/en unknown
-
1967
- 1967-10-06 BE BE704821D patent/BE704821A/xx unknown
- 1967-10-06 GR GR670137761A patent/GR37761B/en unknown
- 1967-10-06 NL NL6713631A patent/NL6713631A/xx unknown
- 1967-10-06 DK DK497967A patent/DK120027B/en unknown
- 1967-10-06 GB GB4570267A patent/GB1202377A/en not_active Expired
- 1967-10-06 ES ES345832A patent/ES345832A1/en not_active Expired
- 1967-10-06 NO NO17002567A patent/NO121048B/no unknown
- 1967-10-06 AT AT910367A patent/AT276358B/en active
Also Published As
Publication number | Publication date |
---|---|
BE704821A (en) | 1968-04-08 |
CH466256A (en) | 1968-12-15 |
NL6713631A (en) | 1968-04-08 |
DK120027B (en) | 1971-03-29 |
NL133741C (en) | |
ES345832A1 (en) | 1968-11-16 |
AT276358B (en) | 1969-11-25 |
GR37761B (en) | 1969-07-12 |
NO121048B (en) | 1971-01-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PE | Patent expired |