GB1202377A - A process for the production of substituted phenyl acetic esters - Google Patents

A process for the production of substituted phenyl acetic esters

Info

Publication number
GB1202377A
GB1202377A GB4570267A GB4570267A GB1202377A GB 1202377 A GB1202377 A GB 1202377A GB 4570267 A GB4570267 A GB 4570267A GB 4570267 A GB4570267 A GB 4570267A GB 1202377 A GB1202377 A GB 1202377A
Authority
GB
United Kingdom
Prior art keywords
hydrogen
group
alkyl
general formula
alkyl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4570267A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JR Geigy AG filed Critical JR Geigy AG
Publication of GB1202377A publication Critical patent/GB1202377A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1,202,377. o-Anilinophenylacetic acid esters. J. R. GEIGY A.G. 6 Oct., 1967, No. 45702/67. Addition to 1,132,318. Heading C2C. o-Anilinophenylacetic acid esters of the general formula wherein R 1 is a C 1-4 alkyl or C 1-4 alkoxy group, a fluorine, chlorine or bromine atom or the trifluoromethyl group; R 2 is hydrogen or is defined as R 1 ; R 3 is hydrogen, a C 1-4 alkyl or C 1-4 alkoxy group or a fluorine, chlorine or bromine atom; R 4 is hydrogen or a C 1-4 alkyl group; R 5 and R 6 are each hydrogen, a C 1-2 alkyl group or the benzyl group or, when R 6 is hydrogen, R 5 may be a C 1-5 alkyl group; and R 7 is a C 1-6 alkyl group or an aralkyl group having at most 3 carbon atoms in the alkyl moiety, are prepared by reaction of an o-nitrophenylacetic acid ester of the general formula with at least double the molar amount of an aryl magnesium halide of the general formula wherein Hal is a bromine or iodine atom, with the proviso that it has a higher atomic number than every halogen atom bound aromatically in the phenyl radical, and decomposition of the intermediate so formed with saturated ammonium chloride solution.
GB4570267A 1966-10-07 1967-10-06 A process for the production of substituted phenyl acetic esters Expired GB1202377A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1451866A CH466256A (en) 1966-10-07 1966-10-07 Process for the preparation of new substituted phenylacetic acid esters

Publications (1)

Publication Number Publication Date
GB1202377A true GB1202377A (en) 1970-08-19

Family

ID=4401499

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4570267A Expired GB1202377A (en) 1966-10-07 1967-10-06 A process for the production of substituted phenyl acetic esters

Country Status (9)

Country Link
AT (1) AT276358B (en)
BE (1) BE704821A (en)
CH (1) CH466256A (en)
DK (1) DK120027B (en)
ES (1) ES345832A1 (en)
GB (1) GB1202377A (en)
GR (1) GR37761B (en)
NL (2) NL6713631A (en)
NO (1) NO121048B (en)

Also Published As

Publication number Publication date
BE704821A (en) 1968-04-08
CH466256A (en) 1968-12-15
NL6713631A (en) 1968-04-08
DK120027B (en) 1971-03-29
NL133741C (en)
ES345832A1 (en) 1968-11-16
AT276358B (en) 1969-11-25
GR37761B (en) 1969-07-12
NO121048B (en) 1971-01-11

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Legal Events

Date Code Title Description
PS Patent sealed
PE Patent expired