GB1187113A - Gona-1,3,5(10)6,8,14-Hexaenes - Google Patents

Gona-1,3,5(10)6,8,14-Hexaenes

Info

Publication number
GB1187113A
GB1187113A GB1609267A GB1609267A GB1187113A GB 1187113 A GB1187113 A GB 1187113A GB 1609267 A GB1609267 A GB 1609267A GB 1609267 A GB1609267 A GB 1609267A GB 1187113 A GB1187113 A GB 1187113A
Authority
GB
United Kingdom
Prior art keywords
steroids
formula
april
alkyl
hexaenes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1609267A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp filed Critical American Home Products Corp
Publication of GB1187113A publication Critical patent/GB1187113A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/566—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol having an oxo group in position 17, e.g. estrone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1,187,113. Gona -1,3,5(10),6,8,14 - hexaenes. AMERICAN HOME PRODUCTS CORP. 7 April, 1967 [7 April, 1966; 25 April, 1966], No. 16092/67. Heading C2U. Steroids of the Formula (I) are prepared by dehydrogenation of steroids of the Formula (IV) or cyclodehydration of seco-steroids of the Formula (V), prepared in turn by dehydrogenation of seco-steroids of the Formula (III) (see Specification 1,187,115). Steroids (I) are novel when R<SP>1</SP> (defined below) is not methyl or, if it is methyl, when R is acetyl, butyryl or butyl. Steroids (I) may be converted to steroids (II) (some which are claimed per se in Specification 1,187,114) by catalytic hydrogenation. (R<SP>1</SP> is C 1-6 alkyl; R is H or C 1-6 alkyl or alkanoyl; and the steroids are optionally substituted at the 1-, 2- or 4-positions by an alkyl or alkoxy group or halogen atom.)
GB1609267A 1966-04-07 1967-04-07 Gona-1,3,5(10)6,8,14-Hexaenes Expired GB1187113A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54085766A 1966-04-07 1966-04-07
US54468266A 1966-04-25 1966-04-25

Publications (1)

Publication Number Publication Date
GB1187113A true GB1187113A (en) 1970-04-08

Family

ID=27066539

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1609267A Expired GB1187113A (en) 1966-04-07 1967-04-07 Gona-1,3,5(10)6,8,14-Hexaenes

Country Status (3)

Country Link
JP (1) JPS501270B1 (en)
DE (1) DE1618052C3 (en)
GB (1) GB1187113A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02120334U (en) * 1989-03-16 1990-09-28

Also Published As

Publication number Publication date
JPS501270B1 (en) 1975-01-16
DE1618052B2 (en) 1973-11-15
DE1618052A1 (en) 1972-07-27
DE1618052C3 (en) 1974-06-20

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Legal Events

Date Code Title Description
PS Patent sealed
429A Application made for amendment of specification (sect. 29/1949)
429H Application (made) for amendment of specification now open to opposition (sect. 29/1949)
429D Case decided by the comptroller ** specification amended (sect. 29/1949)
PE Patent expired