GB1180176A - Novel Steroid 21-Esters, their Preparation, and Compositions containing them - Google Patents
Novel Steroid 21-Esters, their Preparation, and Compositions containing themInfo
- Publication number
- GB1180176A GB1180176A GB50297/68A GB5029768A GB1180176A GB 1180176 A GB1180176 A GB 1180176A GB 50297/68 A GB50297/68 A GB 50297/68A GB 5029768 A GB5029768 A GB 5029768A GB 1180176 A GB1180176 A GB 1180176A
- Authority
- GB
- United Kingdom
- Prior art keywords
- esters
- preparation
- compositions containing
- oct
- novel steroid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 150000003431 steroids Chemical class 0.000 title abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229960003957 dexamethasone Drugs 0.000 abstract 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 229960005205 prednisolone Drugs 0.000 abstract 1
- OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 abstract 1
- CPUKWYXYHPOQJH-RDQPJNLGSA-N pregnadiene group Chemical group C=CC1=CC[C@H]2[C@@H]3CCC4CCCC[C@]4(C)[C@H]3CC[C@]12C CPUKWYXYHPOQJH-RDQPJNLGSA-N 0.000 abstract 1
- 150000003128 pregnanes Chemical group 0.000 abstract 1
- 150000003130 pregnenes Chemical group 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 229960005294 triamcinolone Drugs 0.000 abstract 1
- GFNANZIMVAIWHM-OBYCQNJPSA-N triamcinolone Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@]([C@H](O)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 GFNANZIMVAIWHM-OBYCQNJPSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01R—ELECTRICALLY-CONDUCTIVE CONNECTIONS; STRUCTURAL ASSOCIATIONS OF A PLURALITY OF MUTUALLY-INSULATED ELECTRICAL CONNECTING ELEMENTS; COUPLING DEVICES; CURRENT COLLECTORS
- H01R13/00—Details of coupling devices of the kinds covered by groups H01R12/70 or H01R24/00 - H01R33/00
- H01R13/02—Contact members
- H01R13/10—Sockets for co-operation with pins or blades
- H01R13/11—Resilient sockets
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR126488A FR6590M (enExample) | 1967-10-31 | 1967-10-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1180176A true GB1180176A (en) | 1970-02-04 |
Family
ID=8641025
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB50297/68A Expired GB1180176A (en) | 1967-10-31 | 1968-10-23 | Novel Steroid 21-Esters, their Preparation, and Compositions containing them |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3609172A (enExample) |
| BE (1) | BE722711A (enExample) |
| BR (1) | BR6803567D0 (enExample) |
| CH (1) | CH481080A (enExample) |
| ES (1) | ES360114A1 (enExample) |
| FR (1) | FR6590M (enExample) |
| GB (1) | GB1180176A (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4472392A (en) * | 1983-01-21 | 1984-09-18 | The Upjohn Company | Sulfonate containing ester prodrugs of corticosteroids |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4456602A (en) * | 1982-08-23 | 1984-06-26 | The Upjohn Company | Amine containing ester prodrugs of corticosteroids |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3328431A (en) * | 1960-11-10 | 1967-06-27 | Syntex Corp | 6alpha-monofluoromethyl, 6alpha-difluoromethyl and 6alpha-trifluoromethyl progestational hormone derivatives |
-
1967
- 1967-10-31 FR FR126488A patent/FR6590M/fr not_active Expired
-
1968
- 1968-10-22 BE BE722711D patent/BE722711A/xx unknown
- 1968-10-23 US US770081A patent/US3609172A/en not_active Expired - Lifetime
- 1968-10-23 CH CH1581668A patent/CH481080A/fr not_active IP Right Cessation
- 1968-10-23 GB GB50297/68A patent/GB1180176A/en not_active Expired
- 1968-10-28 ES ES360114A patent/ES360114A1/es not_active Expired
- 1968-10-30 BR BR203567/68A patent/BR6803567D0/pt unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4472392A (en) * | 1983-01-21 | 1984-09-18 | The Upjohn Company | Sulfonate containing ester prodrugs of corticosteroids |
Also Published As
| Publication number | Publication date |
|---|---|
| DE1806158B2 (de) | 1977-01-13 |
| BR6803567D0 (pt) | 1973-03-15 |
| BE722711A (enExample) | 1969-04-01 |
| CH481080A (fr) | 1969-11-15 |
| FR6590M (enExample) | 1968-12-30 |
| ES360114A1 (es) | 1970-07-01 |
| US3609172A (en) | 1971-09-28 |
| DE1806158A1 (de) | 1969-08-07 |
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