GB1178279A - Benzyl Sulfone Derivatives and Pharmaceutical Compositions containing them - Google Patents

Benzyl Sulfone Derivatives and Pharmaceutical Compositions containing them

Info

Publication number
GB1178279A
GB1178279A GB34867/67A GB3486767A GB1178279A GB 1178279 A GB1178279 A GB 1178279A GB 34867/67 A GB34867/67 A GB 34867/67A GB 3486767 A GB3486767 A GB 3486767A GB 1178279 A GB1178279 A GB 1178279A
Authority
GB
United Kingdom
Prior art keywords
alkyl
alkoxy
amino
dichlorobenzyl
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB34867/67A
Other languages
English (en)
Inventor
Tsung-Ying Shen
Clifford Henry Shunk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1178279A publication Critical patent/GB1178279A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/24—Sulfones; Sulfoxides having sulfone or sulfoxide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/02—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to acyclic carbon atoms
    • C07C317/10—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C317/18—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/28—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GB34867/67A 1966-08-01 1967-07-28 Benzyl Sulfone Derivatives and Pharmaceutical Compositions containing them Expired GB1178279A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56903966A 1966-08-01 1966-08-01

Publications (1)

Publication Number Publication Date
GB1178279A true GB1178279A (en) 1970-01-21

Family

ID=24273843

Family Applications (1)

Application Number Title Priority Date Filing Date
GB34867/67A Expired GB1178279A (en) 1966-08-01 1967-07-28 Benzyl Sulfone Derivatives and Pharmaceutical Compositions containing them

Country Status (5)

Country Link
US (1) US3689567A (enExample)
BE (1) BE702104A (enExample)
FR (2) FR1563655A (enExample)
GB (1) GB1178279A (enExample)
NL (1) NL6710403A (enExample)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4064178A (en) 1975-05-19 1977-12-20 Ppg Industries, Inc. Bis(4-chlorophenyl)methyl methyl sulfoxide
US4103031A (en) 1976-06-30 1978-07-25 Ppg Industries, Inc. Control of plant pests with bis(4-chlorophenyl)methyl methyl sulfoxide
US4117168A (en) 1976-07-07 1978-09-26 Ppg Industries, Inc. Antifungal di(aryl)methyl alkyl sulfones
US4440964A (en) * 1982-03-17 1984-04-03 Monsanto Company Substituted 2-alkylsulfonylalkyl nitrobenzenes and process for their preparation
EP1586559A1 (en) * 2004-04-13 2005-10-19 Cephalon, Inc. Biaryl-methanethio-, -sulphinyl- and sulphonyl derivatives
EP1586560A1 (en) * 2004-04-13 2005-10-19 Cephalon, Inc. Thio-substituted arylmethanesulfinyl derivatives
US7297817B2 (en) 2004-04-13 2007-11-20 Cephalon France Thio-substituted arylmethanesulfinyl derivatives
US7449481B2 (en) 2004-04-13 2008-11-11 Cephalon, Inc. Thio-substituted biaryl-methanesulfinyl derivatives

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4160096A (en) * 1974-04-19 1979-07-03 Crc Compagnia Di Ricerca Cimica S.A. Process for production of 5-nitroimidazole derivatives
US4006183A (en) * 1975-07-08 1977-02-01 Sandoz, Inc. Substituted α-methylsulfinyl-o-toluidines
US4144248A (en) 1976-03-04 1979-03-13 Sagami Chemical Research Center Aromatic acetic acid derivatives having sulfur atom at alpha-position and process for their preparation
US4084005A (en) * 1976-10-27 1978-04-11 Ppg Industries, Inc. Control of the harmful effects of Fusarium upon plants
US4940812A (en) * 1989-07-17 1990-07-10 Eastman Kodak Company 5-substituted aminophenols
US5538812A (en) * 1994-02-04 1996-07-23 Moltech Corporation Electrolyte materials containing highly dissociated metal ion salts
WO2003010137A1 (en) * 2001-07-24 2003-02-06 Merck & Co., Inc. Preparation of sulfonyl quinoline

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4064178A (en) 1975-05-19 1977-12-20 Ppg Industries, Inc. Bis(4-chlorophenyl)methyl methyl sulfoxide
US4067909A (en) 1975-05-19 1978-01-10 Ppg Industries, Inc. Novel di(aryl)methyl alkyl sulfones
US4103031A (en) 1976-06-30 1978-07-25 Ppg Industries, Inc. Control of plant pests with bis(4-chlorophenyl)methyl methyl sulfoxide
US4117168A (en) 1976-07-07 1978-09-26 Ppg Industries, Inc. Antifungal di(aryl)methyl alkyl sulfones
US4440964A (en) * 1982-03-17 1984-04-03 Monsanto Company Substituted 2-alkylsulfonylalkyl nitrobenzenes and process for their preparation
EP1586559A1 (en) * 2004-04-13 2005-10-19 Cephalon, Inc. Biaryl-methanethio-, -sulphinyl- and sulphonyl derivatives
EP1586560A1 (en) * 2004-04-13 2005-10-19 Cephalon, Inc. Thio-substituted arylmethanesulfinyl derivatives
US7297817B2 (en) 2004-04-13 2007-11-20 Cephalon France Thio-substituted arylmethanesulfinyl derivatives
US7449481B2 (en) 2004-04-13 2008-11-11 Cephalon, Inc. Thio-substituted biaryl-methanesulfinyl derivatives
US7981907B2 (en) 2004-04-13 2011-07-19 Cephalon, Inc. Thio-substituted biarylmethanesulfinyl derivatives
US8071604B2 (en) 2004-04-13 2011-12-06 Cephalon France Thio-substituted arylmethanesulfinyl derivatives

Also Published As

Publication number Publication date
US3689567A (en) 1972-09-05
FR7179M (enExample) 1969-08-11
BE702104A (enExample) 1968-01-31
FR1563655A (enExample) 1969-04-18
NL6710403A (enExample) 1968-02-02

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