GB1175797A - Amide Derivatives of Morphine and their preparation - Google Patents
Amide Derivatives of Morphine and their preparationInfo
- Publication number
- GB1175797A GB1175797A GB25077/68A GB2507768A GB1175797A GB 1175797 A GB1175797 A GB 1175797A GB 25077/68 A GB25077/68 A GB 25077/68A GB 2507768 A GB2507768 A GB 2507768A GB 1175797 A GB1175797 A GB 1175797A
- Authority
- GB
- United Kingdom
- Prior art keywords
- substances
- morphine
- alkyl
- contain
- dimethylamino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 Amide Derivatives of Morphine Chemical class 0.000 title abstract 4
- 239000000126 substance Substances 0.000 abstract 3
- KWGRBVOPPLSCSI-WPRPVWTQSA-N (-)-ephedrine Chemical compound CN[C@@H](C)[C@H](O)C1=CC=CC=C1 KWGRBVOPPLSCSI-WPRPVWTQSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical class O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 abstract 2
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 abstract 1
- 206010011224 Cough Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 229940051880 analgesics and antipyretics pyrazolones Drugs 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 239000002221 antipyretic Substances 0.000 abstract 1
- 230000003182 bronchodilatating effect Effects 0.000 abstract 1
- SOYKEARSMXGVTM-UHFFFAOYSA-N chlorphenamine Chemical compound C=1C=CC=NC=1C(CCN(C)C)C1=CC=C(Cl)C=C1 SOYKEARSMXGVTM-UHFFFAOYSA-N 0.000 abstract 1
- KWGRBVOPPLSCSI-UHFFFAOYSA-N d-ephedrine Natural products CNC(C)C(O)C1=CC=CC=C1 KWGRBVOPPLSCSI-UHFFFAOYSA-N 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229960002179 ephedrine Drugs 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229960005181 morphine Drugs 0.000 abstract 1
- CKIPCLCBYTWUEZ-UHFFFAOYSA-N n,n-dimethyl-2-phenothiazin-10-ylethanamine;hydrochloride Chemical compound Cl.C1=CC=C2N(CCN(C)C)C3=CC=CC=C3SC2=C1 CKIPCLCBYTWUEZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229960001802 phenylephrine Drugs 0.000 abstract 1
- SONNWYBIRXJNDC-VIFPVBQESA-N phenylephrine Chemical compound CNC[C@H](O)C1=CC=CC(O)=C1 SONNWYBIRXJNDC-VIFPVBQESA-N 0.000 abstract 1
- 210000002345 respiratory system Anatomy 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR108086 | 1967-05-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1175797A true GB1175797A (en) | 1969-12-23 |
Family
ID=8631747
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB25077/68A Expired GB1175797A (en) | 1967-05-26 | 1968-05-24 | Amide Derivatives of Morphine and their preparation |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3632580A (forum.php) |
| AT (1) | AT285830B (forum.php) |
| BE (1) | BE715659A (forum.php) |
| CH (1) | CH485730A (forum.php) |
| DE (1) | DE1770493A1 (forum.php) |
| DK (1) | DK118087B (forum.php) |
| ES (2) | ES354319A1 (forum.php) |
| FR (1) | FR1566164A (forum.php) |
| GB (1) | GB1175797A (forum.php) |
| LU (1) | LU56141A1 (forum.php) |
| NL (1) | NL6807361A (forum.php) |
| SE (1) | SE338051B (forum.php) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4122181A (en) | 1975-12-19 | 1978-10-24 | Pierre Fabre S.A. | Analgesic (3-micotinamido-N(quinolyl) anthranilates and method of use |
-
1967
- 1967-05-26 FR FR108086A patent/FR1566164A/fr not_active Expired
-
1968
- 1968-05-17 AT AT478868A patent/AT285830B/de not_active IP Right Cessation
- 1968-05-17 US US729923A patent/US3632580A/en not_active Expired - Lifetime
- 1968-05-21 SE SE06851/68A patent/SE338051B/xx unknown
- 1968-05-22 CH CH760268A patent/CH485730A/fr not_active IP Right Cessation
- 1968-05-24 NL NL6807361A patent/NL6807361A/xx unknown
- 1968-05-24 GB GB25077/68A patent/GB1175797A/en not_active Expired
- 1968-05-24 DK DK244168AA patent/DK118087B/da unknown
- 1968-05-24 LU LU56141D patent/LU56141A1/xx unknown
- 1968-05-24 BE BE715659D patent/BE715659A/xx unknown
- 1968-05-25 DE DE19681770493 patent/DE1770493A1/de active Pending
- 1968-05-25 ES ES354319A patent/ES354319A1/es not_active Expired
- 1968-10-17 ES ES359249A patent/ES359249A1/es not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4122181A (en) | 1975-12-19 | 1978-10-24 | Pierre Fabre S.A. | Analgesic (3-micotinamido-N(quinolyl) anthranilates and method of use |
Also Published As
| Publication number | Publication date |
|---|---|
| ES354319A1 (es) | 1969-11-01 |
| CH485730A (fr) | 1970-02-15 |
| DK118087B (da) | 1970-07-06 |
| FR1566164A (forum.php) | 1969-05-09 |
| NL6807361A (forum.php) | 1968-11-27 |
| ES359249A1 (es) | 1970-06-01 |
| BE715659A (forum.php) | 1968-10-16 |
| LU56141A1 (forum.php) | 1968-09-11 |
| US3632580A (en) | 1972-01-04 |
| AT285830B (de) | 1970-11-10 |
| SE338051B (forum.php) | 1971-08-30 |
| DE1770493A1 (de) | 1972-03-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |