GB1174349A - Novel 2-Anilinomethylimidazoline Derivatives and process for the preparation thereof - Google Patents
Novel 2-Anilinomethylimidazoline Derivatives and process for the preparation thereofInfo
- Publication number
- GB1174349A GB1174349A GB38564/67A GB3856467A GB1174349A GB 1174349 A GB1174349 A GB 1174349A GB 38564/67 A GB38564/67 A GB 38564/67A GB 3856467 A GB3856467 A GB 3856467A GB 1174349 A GB1174349 A GB 1174349A
- Authority
- GB
- United Kingdom
- Prior art keywords
- anilinomethyl
- acid addition
- imidazoline
- physiologically compatible
- compatible acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- FPZTYKLEJPXTKD-UHFFFAOYSA-N n-(4,5-dihydro-1h-imidazol-2-ylmethyl)aniline Chemical class N=1CCNC=1CNC1=CC=CC=C1 FPZTYKLEJPXTKD-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 239000000460 chlorine Substances 0.000 abstract 2
- 229910052731 fluorine Inorganic materials 0.000 abstract 2
- 239000011737 fluorine Substances 0.000 abstract 2
- 229940083254 peripheral vasodilators imidazoline derivative Drugs 0.000 abstract 2
- 208000001953 Hypotension Diseases 0.000 abstract 1
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N N-phenyl amine Natural products NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002490 anilino group Chemical class [H]N(*)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
- 239000005526 vasoconstrictor agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D233/24—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEB0088625 | 1966-08-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1174349A true GB1174349A (en) | 1969-12-17 |
Family
ID=6984390
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB38564/67A Expired GB1174349A (en) | 1966-08-25 | 1967-08-22 | Novel 2-Anilinomethylimidazoline Derivatives and process for the preparation thereof |
Country Status (3)
| Country | Link |
|---|---|
| DK (1) | DK115849B (enrdf_load_stackoverflow) |
| FR (2) | FR1549283A (enrdf_load_stackoverflow) |
| GB (1) | GB1174349A (enrdf_load_stackoverflow) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4036972A (en) * | 1973-02-23 | 1977-07-19 | Boehringer Ingelheim Gmbh | 2-(N-thienylmethyl-phenylamino)-imidazolines-(2) and salts thereof |
| DE2750902A1 (de) * | 1976-11-16 | 1978-05-24 | Ciba Geigy Ag | Schaedlingsbekaempfungsmittel, insbesondere zur bekaempfung von ektoparasiten und mikroorganismen |
| US4226876A (en) * | 1976-12-20 | 1980-10-07 | Burroughs Wellcome Co. | Arthropodicidal imidazoline derivatives |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE755270A (fr) * | 1969-08-27 | 1971-02-25 | Sandoz Sa | Nouveaux derives du benzo(cd)indole, leur preparation et medicaments contenant ces derives |
| JPS5395969A (en) * | 1976-12-20 | 1978-08-22 | Wellcome Found | Imidazoline derivative and insecticide containing same |
| US4292429A (en) * | 1978-03-08 | 1981-09-29 | Ciba-Geigy Corporation | Imidazole urea and amido compounds |
| FR2549049B1 (fr) * | 1983-07-13 | 1986-06-20 | Chauvin Blache Lab | Nouvelles amidines, leur procede de preparation et leur application therapeutique |
-
1967
- 1967-08-22 GB GB38564/67A patent/GB1174349A/en not_active Expired
- 1967-08-24 DK DK429167A patent/DK115849B/da unknown
- 1967-08-25 FR FR1549283D patent/FR1549283A/fr not_active Expired
- 1967-11-24 FR FR129664A patent/FR7264M/fr not_active Expired
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4036972A (en) * | 1973-02-23 | 1977-07-19 | Boehringer Ingelheim Gmbh | 2-(N-thienylmethyl-phenylamino)-imidazolines-(2) and salts thereof |
| DE2750902A1 (de) * | 1976-11-16 | 1978-05-24 | Ciba Geigy Ag | Schaedlingsbekaempfungsmittel, insbesondere zur bekaempfung von ektoparasiten und mikroorganismen |
| US4254133A (en) | 1976-11-16 | 1981-03-03 | Ciba-Geigy Corporation | Combatting ectoparasites with phenylaminoalkyl-2-imidazoline compounds |
| US4226876A (en) * | 1976-12-20 | 1980-10-07 | Burroughs Wellcome Co. | Arthropodicidal imidazoline derivatives |
Also Published As
| Publication number | Publication date |
|---|---|
| FR7264M (enrdf_load_stackoverflow) | 1969-09-15 |
| FR1549283A (enrdf_load_stackoverflow) | 1968-12-13 |
| DK115849B (da) | 1969-11-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |