GB1173373A - Substituted 3-Aminopyrrolidines - Google Patents
Substituted 3-AminopyrrolidinesInfo
- Publication number
- GB1173373A GB1173373A GB1297667A GB1297667A GB1173373A GB 1173373 A GB1173373 A GB 1173373A GB 1297667 A GB1297667 A GB 1297667A GB 1297667 A GB1297667 A GB 1297667A GB 1173373 A GB1173373 A GB 1173373A
- Authority
- GB
- United Kingdom
- Prior art keywords
- general formula
- benzyl
- reacting
- pyrrolidines
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NGXSWUFDCSEIOO-UHFFFAOYSA-N pyrrolidin-3-amine Chemical class NC1CCNC1 NGXSWUFDCSEIOO-UHFFFAOYSA-N 0.000 title 1
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- 150000003235 pyrrolidines Chemical class 0.000 abstract 3
- YQMXOIAIYXXXEE-UHFFFAOYSA-N 1-benzylpyrrolidin-3-ol Chemical compound C1C(O)CCN1CC1=CC=CC=C1 YQMXOIAIYXXXEE-UHFFFAOYSA-N 0.000 abstract 2
- YDNMHDRXNOHCJH-UHFFFAOYSA-N 3-aminopyrrolidine-2,5-dione Chemical compound NC1CC(=O)NC1=O YDNMHDRXNOHCJH-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- -1 trifluoromethylphenyl Chemical group 0.000 abstract 2
- 125000003161 (C1-C6) alkylene group Chemical group 0.000 abstract 1
- CWEGCQIIDCZZED-UHFFFAOYSA-N 1-benzylpyrrolidine Chemical compound C=1C=CC=CC=1CN1CCCC1 CWEGCQIIDCZZED-UHFFFAOYSA-N 0.000 abstract 1
- BNPFHEFZJPVCCE-UHFFFAOYSA-N 2,5-dioxopyrrole-1-carboxamide Chemical compound NC(=O)N1C(=O)C=CC1=O BNPFHEFZJPVCCE-UHFFFAOYSA-N 0.000 abstract 1
- 125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- PEEHTFAAVSWFBL-UHFFFAOYSA-N Maleimide Chemical compound O=C1NC(=O)C=C1 PEEHTFAAVSWFBL-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000005036 alkoxyphenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000005037 alkyl phenyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 239000003874 central nervous system depressant Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000005059 halophenyl group Chemical group 0.000 abstract 1
- 239000012280 lithium aluminium hydride Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- SNHOURMNEXCAJV-UHFFFAOYSA-N sulfuryl dichloride;toluene Chemical compound ClS(Cl)(=O)=O.CC1=CC=CC=C1 SNHOURMNEXCAJV-UHFFFAOYSA-N 0.000 abstract 1
- 239000003204 tranquilizing agent Substances 0.000 abstract 1
- 230000002936 tranquilizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
- C07D207/444—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
- C07D207/448—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53629166A | 1966-03-22 | 1966-03-22 | |
| US53629966A | 1966-03-22 | 1966-03-22 | |
| US53631666A | 1966-03-22 | 1966-03-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1173373A true GB1173373A (en) | 1969-12-10 |
Family
ID=27415206
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1297667A Expired GB1173373A (en) | 1966-03-22 | 1967-03-20 | Substituted 3-Aminopyrrolidines |
Country Status (8)
| Country | Link |
|---|---|
| BE (1) | BE695817A (enrdf_load_stackoverflow) |
| CH (1) | CH491908A (enrdf_load_stackoverflow) |
| DE (1) | DE1695628A1 (enrdf_load_stackoverflow) |
| ES (1) | ES338316A1 (enrdf_load_stackoverflow) |
| FR (1) | FR1551862A (enrdf_load_stackoverflow) |
| GB (1) | GB1173373A (enrdf_load_stackoverflow) |
| NL (1) | NL6704178A (enrdf_load_stackoverflow) |
| SE (1) | SE308721B (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003005824A3 (de) * | 2001-07-11 | 2003-05-01 | Bayer Cropscience Gmbh | Substituierte 3-heteroaryl(amino-oder oxy)-pyrrolidin-2-one, verfahren zu deren herstellung und verwendung als herbizide oder als pflanzenwachstumsregulatoren |
| US8084442B2 (en) | 2005-05-13 | 2011-12-27 | Otsuka Pharmaceutical Co., Ltd. | N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors |
-
1967
- 1967-03-20 BE BE695817D patent/BE695817A/xx unknown
- 1967-03-20 SE SE384267A patent/SE308721B/xx unknown
- 1967-03-20 GB GB1297667A patent/GB1173373A/en not_active Expired
- 1967-03-21 NL NL6704178A patent/NL6704178A/xx unknown
- 1967-03-21 DE DE19671695628 patent/DE1695628A1/de active Pending
- 1967-03-21 ES ES338316A patent/ES338316A1/es not_active Expired
- 1967-03-22 FR FR1551862D patent/FR1551862A/fr not_active Expired
- 1967-03-22 CH CH414667A patent/CH491908A/de not_active IP Right Cessation
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003005824A3 (de) * | 2001-07-11 | 2003-05-01 | Bayer Cropscience Gmbh | Substituierte 3-heteroaryl(amino-oder oxy)-pyrrolidin-2-one, verfahren zu deren herstellung und verwendung als herbizide oder als pflanzenwachstumsregulatoren |
| US8084442B2 (en) | 2005-05-13 | 2011-12-27 | Otsuka Pharmaceutical Co., Ltd. | N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors |
| US8420623B2 (en) | 2005-05-13 | 2013-04-16 | Otsuka Pharmaceutical Co., Ltd. | N, N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors |
| EP1881975B1 (en) * | 2005-05-13 | 2014-01-08 | Otsuka Pharmaceutical Co., Ltd. | N,n-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors |
| US8815871B2 (en) | 2005-05-13 | 2014-08-26 | Otsuka Pharmaceutical Co., Ltd. | N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors |
| US9611214B2 (en) | 2005-05-13 | 2017-04-04 | Otsuka Pharmaceutical Co., Ltd. | N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors |
| US10000450B2 (en) | 2005-05-13 | 2018-06-19 | Otsuka Pharmaceutical Co., Ltd. | N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors |
Also Published As
| Publication number | Publication date |
|---|---|
| ES338316A1 (es) | 1968-06-16 |
| NL6704178A (enrdf_load_stackoverflow) | 1967-09-25 |
| BE695817A (enrdf_load_stackoverflow) | 1967-09-01 |
| FR1551862A (enrdf_load_stackoverflow) | 1969-01-03 |
| DE1695628A1 (de) | 1971-04-22 |
| CH491908A (de) | 1970-06-15 |
| SE308721B (enrdf_load_stackoverflow) | 1969-02-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed |