GB1163355A - Preparation of 5-Substituted Tetrazoles - Google Patents
Preparation of 5-Substituted TetrazolesInfo
- Publication number
- GB1163355A GB1163355A GB1964967A GB1964967A GB1163355A GB 1163355 A GB1163355 A GB 1163355A GB 1964967 A GB1964967 A GB 1964967A GB 1964967 A GB1964967 A GB 1964967A GB 1163355 A GB1163355 A GB 1163355A
- Authority
- GB
- United Kingdom
- Prior art keywords
- substituted
- tetrazoles
- alkyl
- formula
- phenyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1,163,355. Tetrazoles. BORG-WARNER CORP. 28 April, 1967 [17 May, 1966], No. 19649/67. Heading C2C. 5-Substituted tetrazoles of the formula in which the broken line represents the second double bond either in the 2, 3 or 3, 4 position, R represents an alkyl or cycloalkyl group, containing up to 6 carbon atoms, or a phenyl group or substituted phenyl group of formula in which R<SP>1</SP> and R<SP>11</SP> represent hydrogen or an alkyl, nitro or nitroso group, are prepared by heating a mixture of a nitrile compound RCN with a Friedel-Crafts catalyst and a metal azide in the absence of a solvent to 60-130‹ C., adding a dilute aqueous inorganic acid to hydrolyse the reaction product, steam distilling the aqueous hydrolysate to remove any unreacted nitrile, and recovering crystals of the 5-substituted tetrazole from the aqueous hydrolysate. Suitable nitriles are, for example, benzonitrile ; o-, m- or p-toluonitrile and butyronitrile. Azides which may be used are those of sodium, potassium, lithium, calcium and magnesium.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US55064866A | 1966-05-17 | 1966-05-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1163355A true GB1163355A (en) | 1969-09-04 |
Family
ID=24198032
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1964967A Expired GB1163355A (en) | 1966-05-17 | 1967-04-28 | Preparation of 5-Substituted Tetrazoles |
Country Status (2)
Country | Link |
---|---|
DE (1) | DE1670220A1 (en) |
GB (1) | GB1163355A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2517676A1 (en) * | 1981-12-07 | 1983-06-10 | Delalande Sa | NOVEL TETRAZOLIC DERIVATIVES SUBSTITUTED IN POSITION 5, PROCESS FOR PREPARING THEM AND THEIR THERAPEUTIC USE |
FR2631827A1 (en) * | 1988-05-27 | 1989-12-01 | Delalande Sa | NOVEL (HETERO) ARYL-5 TETRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC USE THEREOF |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2657610A1 (en) * | 1990-01-29 | 1991-08-02 | Rhone Poulenc Agrochimie | TRIAZOLOPYRIDINES HERBICIDES. |
-
1967
- 1967-04-28 GB GB1964967A patent/GB1163355A/en not_active Expired
- 1967-05-05 DE DE19671670220 patent/DE1670220A1/en active Pending
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2517676A1 (en) * | 1981-12-07 | 1983-06-10 | Delalande Sa | NOVEL TETRAZOLIC DERIVATIVES SUBSTITUTED IN POSITION 5, PROCESS FOR PREPARING THEM AND THEIR THERAPEUTIC USE |
FR2631827A1 (en) * | 1988-05-27 | 1989-12-01 | Delalande Sa | NOVEL (HETERO) ARYL-5 TETRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC USE THEREOF |
EP0348257A2 (en) * | 1988-05-27 | 1989-12-27 | Delalande S.A. | (Hetero)aryl-diazole derivatives, process for their preparation and their therapeutical use |
EP0348257A3 (en) * | 1988-05-27 | 1990-03-28 | Delalande S.A. | (hetero)aryl-diazole derivatives, process for their preparation and their therapeutical use |
US5100910A (en) * | 1988-05-27 | 1992-03-31 | Delalande S.A. | Aryl substituted tetrazole derivatives, and application thereof in therapeutics |
Also Published As
Publication number | Publication date |
---|---|
DE1670220A1 (en) | 1972-01-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PLNP | Patent lapsed through nonpayment of renewal fees |