GB1161437A - Thiazino-Isoquinoline Derivatives - Google Patents
Thiazino-Isoquinoline DerivativesInfo
- Publication number
- GB1161437A GB1161437A GB51831/67A GB5183167A GB1161437A GB 1161437 A GB1161437 A GB 1161437A GB 51831/67 A GB51831/67 A GB 51831/67A GB 5183167 A GB5183167 A GB 5183167A GB 1161437 A GB1161437 A GB 1161437A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- formula
- thiazino
- nov
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- NKSZCPBUWGZONP-UHFFFAOYSA-N 3,4-dihydroisoquinoline Chemical class C1=CC=C2C=NCCC2=C1 NKSZCPBUWGZONP-UHFFFAOYSA-N 0.000 abstract 1
- DKIDEFUBRARXTE-UHFFFAOYSA-N 3-mercaptopropanoic acid Chemical compound OC(=O)CCS DKIDEFUBRARXTE-UHFFFAOYSA-N 0.000 abstract 1
- ATTZFSUZZUNHBP-UHFFFAOYSA-N Piperonyl sulfoxide Chemical compound CCCCCCCCS(=O)C(C)CC1=CC=C2OCOC2=C1 ATTZFSUZZUNHBP-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 125000001174 sulfone group Chemical group 0.000 abstract 1
- 230000002963 trichomonacidal effect Effects 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59440466A | 1966-11-15 | 1966-11-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1161437A true GB1161437A (en) | 1969-08-13 |
Family
ID=24378724
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB51831/67A Expired GB1161437A (en) | 1966-11-15 | 1967-11-14 | Thiazino-Isoquinoline Derivatives |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US3455933A (https=) |
| CH (1) | CH479612A (https=) |
| FR (1) | FR1552211A (https=) |
| GB (1) | GB1161437A (https=) |
| NL (1) | NL6715510A (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4062850A (en) * | 1973-05-30 | 1977-12-13 | Chinoin Pharmaceutical And Chemical Works Ltd. | Thiazoloisoquinolines with coronary and respiratory effects |
| US4163786A (en) * | 1973-05-30 | 1979-08-07 | Chinoin Pharmaceutical And Chemical Works Ltd. | Thiazoloisoquinolines with coronary and respiratory effects |
| HU170680B (https=) * | 1973-05-30 | 1977-08-28 | ||
| NL169076C (nl) * | 1975-08-06 | 1982-06-01 | Rhone Poulenc Ind | Werkwijze voor het bereiden of vervaardigen van farmacologische preparaten met een analgetische en antipyretische werking, alsmede werkwijze voor het bereiden van geneeskrachtige verbindingen, welke geschikt zijn voor gebruik in dergelijke preparaten. |
| US4108999A (en) * | 1977-02-22 | 1978-08-22 | Rhone-Poulenc Industries | Thiazolo[3,4-b]isoquinoline derivatives, pharmaceutical compositions containing them and pharmaceutical methods using them |
| HU178454B (en) * | 1979-07-02 | 1982-05-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing new isoquinoline derivatives containing sulphur |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2985649A (en) * | 1959-09-17 | 1961-05-23 | Pfizer & Co C | Derivatives of thiabenzopyrrocoline, thiabenzopyridocoline and thiazepine |
-
1966
- 1966-11-15 US US594404A patent/US3455933A/en not_active Expired - Lifetime
-
1967
- 1967-11-14 GB GB51831/67A patent/GB1161437A/en not_active Expired
- 1967-11-14 CH CH1589467A patent/CH479612A/fr not_active IP Right Cessation
- 1967-11-15 FR FR1552211D patent/FR1552211A/fr not_active Expired
- 1967-11-15 NL NL6715510A patent/NL6715510A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR1552211A (https=) | 1969-01-03 |
| US3455933A (en) | 1969-07-15 |
| NL6715510A (https=) | 1968-05-16 |
| CH479612A (fr) | 1969-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |