GB1156465A - Prostaglandins - Google Patents
ProstaglandinsInfo
- Publication number
- GB1156465A GB1156465A GB749567A GB749567A GB1156465A GB 1156465 A GB1156465 A GB 1156465A GB 749567 A GB749567 A GB 749567A GB 749567 A GB749567 A GB 749567A GB 1156465 A GB1156465 A GB 1156465A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acids
- prostaglandins
- prepared
- salts
- esters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940094443 oxytocics prostaglandins Drugs 0.000 title abstract 5
- 150000003180 prostaglandins Chemical class 0.000 title abstract 4
- 239000002253 acid Substances 0.000 abstract 7
- 150000007513 acids Chemical class 0.000 abstract 5
- 150000003839 salts Chemical class 0.000 abstract 3
- NLRIJHGYFNZMGB-UHFFFAOYSA-N 8-nonynoic acid Chemical compound OC(=O)CCCCCCC#C NLRIJHGYFNZMGB-UHFFFAOYSA-N 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 abstract 2
- ZYJDXFLOQUBABE-UHFFFAOYSA-N 1-bromodeca-2,5-diyne Chemical compound CCCCC#CCC#CCBr ZYJDXFLOQUBABE-UHFFFAOYSA-N 0.000 abstract 1
- PLBPPUBDYCUEGP-UHFFFAOYSA-N 1-bromododeca-2,5-diyne Chemical compound CCCCCCC#CCC#CCBr PLBPPUBDYCUEGP-UHFFFAOYSA-N 0.000 abstract 1
- -1 6 - carboxyhexyl Chemical group 0.000 abstract 1
- 238000006218 Arndt-Eistert homologation reaction Methods 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 108010024636 Glutathione Proteins 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 241001494479 Pecora Species 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 210000004907 gland Anatomy 0.000 abstract 1
- 229960003180 glutathione Drugs 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 238000011534 incubation Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- FRIJBUGBVQZNTB-UHFFFAOYSA-M magnesium;ethane;bromide Chemical compound [Mg+2].[Br-].[CH2-]C FRIJBUGBVQZNTB-UHFFFAOYSA-M 0.000 abstract 1
- 150000004702 methyl esters Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P31/00—Preparation of compounds containing a five-membered ring having two side-chains in ortho position to each other, and having at least one oxygen atom directly bound to the ring in ortho position to one of the side-chains, one side-chain containing, not directly bound to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having at least one oxygen atom bound in gamma-position to the ring, e.g. prostaglandins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/353—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by isomerisation; by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/36—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by hydrogenation of carbon-to-carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/64—Acyl halides
- C07C57/66—Acyl halides with only carbon-to-carbon double bonds as unsaturation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB749567A GB1156465A (en) | 1967-02-16 | 1967-02-16 | Prostaglandins |
| FR1560642D FR1560642A (enrdf_load_stackoverflow) | 1967-02-16 | 1968-02-15 | |
| CH231868A CH527150A (de) | 1967-02-16 | 1968-02-16 | Verfahren zur Herstellung von Derivaten von 3-Hydroxycyclopentanonen und deren Verwendung |
| DE1968U0014673 DE1668809C3 (de) | 1967-02-16 | 1968-02-16 | Prostaglandinverbindungen, Verfahren zu deren Herstellung und sie enthaltende therapeutische Mittel |
| BE710918D BE710918A (enrdf_load_stackoverflow) | 1967-02-16 | 1968-02-16 | |
| NL6802212A NL159375B (nl) | 1967-02-16 | 1968-02-16 | Werkwijze ter bereiding van een farmaceutisch preparaat op basis van een prostaglandine van de e-reeks, gevormd preparaat, bereid volgens deze werkwijze, alsmede werkwijze ter bereiding van prostaglandinederivaten van de e-reeks. |
| FR151646A FR7885M (enrdf_load_stackoverflow) | 1967-02-16 | 1968-05-14 | |
| US05/343,269 US4163108A (en) | 1967-02-16 | 1973-03-21 | Prostaglandins |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB749567A GB1156465A (en) | 1967-02-16 | 1967-02-16 | Prostaglandins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1156465A true GB1156465A (en) | 1969-06-25 |
Family
ID=9834220
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB749567A Expired GB1156465A (en) | 1967-02-16 | 1967-02-16 | Prostaglandins |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE710918A (enrdf_load_stackoverflow) |
| CH (1) | CH527150A (enrdf_load_stackoverflow) |
| DE (1) | DE1668809C3 (enrdf_load_stackoverflow) |
| FR (2) | FR1560642A (enrdf_load_stackoverflow) |
| GB (1) | GB1156465A (enrdf_load_stackoverflow) |
| NL (1) | NL159375B (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017223447A1 (en) | 2016-06-23 | 2017-12-28 | The Regents Of The University Of Michigan | 12(s)-hydroxyeicosatrienoic acid compounds and their use as therapeutic agents |
| US20230097753A1 (en) * | 2020-01-29 | 2023-03-30 | Universitat De Les Illes Balears | Alpha-hydroxylated fatty-acid metabolites, medical uses and use as biomarkers |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5262437A (en) * | 1990-12-10 | 1993-11-16 | Allergan, Inc. | Homo-prostaglandin derivatives as ocular hypotensives |
| HUT64305A (en) * | 1990-12-10 | 1993-12-28 | Allergan Inc | Method for producing homo-prostagladine derivatives and pharmaceutical preparatives containing them |
| JPH10130196A (ja) * | 1996-10-29 | 1998-05-19 | Toray Dow Corning Silicone Co Ltd | 脂肪酸クロライドの製造方法 |
-
1967
- 1967-02-16 GB GB749567A patent/GB1156465A/en not_active Expired
-
1968
- 1968-02-15 FR FR1560642D patent/FR1560642A/fr not_active Expired
- 1968-02-16 NL NL6802212A patent/NL159375B/xx unknown
- 1968-02-16 BE BE710918D patent/BE710918A/xx not_active IP Right Cessation
- 1968-02-16 CH CH231868A patent/CH527150A/de not_active IP Right Cessation
- 1968-02-16 DE DE1968U0014673 patent/DE1668809C3/de not_active Expired
- 1968-05-14 FR FR151646A patent/FR7885M/fr not_active Expired
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017223447A1 (en) | 2016-06-23 | 2017-12-28 | The Regents Of The University Of Michigan | 12(s)-hydroxyeicosatrienoic acid compounds and their use as therapeutic agents |
| EP3475442A4 (en) * | 2016-06-23 | 2019-12-04 | The Regents of The University of Michigan | 12 (S) -HYDROXYEICOSATRIC ACID COMPOUNDS AND THEIR USE AS THERAPEUTICS |
| US11111222B2 (en) | 2016-06-23 | 2021-09-07 | The Regents Of The University Of Michigan | Hydroxyeicosatrienoic acid compounds and their use as therapeutic agents |
| US20230097753A1 (en) * | 2020-01-29 | 2023-03-30 | Universitat De Les Illes Balears | Alpha-hydroxylated fatty-acid metabolites, medical uses and use as biomarkers |
Also Published As
| Publication number | Publication date |
|---|---|
| NL6802212A (enrdf_load_stackoverflow) | 1968-08-19 |
| DE1668809A1 (de) | 1971-09-30 |
| NL159375B (nl) | 1979-02-15 |
| CH527150A (de) | 1972-08-31 |
| FR1560642A (enrdf_load_stackoverflow) | 1969-03-21 |
| FR7885M (enrdf_load_stackoverflow) | 1970-05-04 |
| DE1668809B2 (de) | 1979-07-12 |
| DE1668809C3 (de) | 1980-03-27 |
| BE710918A (enrdf_load_stackoverflow) | 1968-08-16 |
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