GB1153570A - Indolyl Alkanol Esters - Google Patents
Indolyl Alkanol EstersInfo
- Publication number
- GB1153570A GB1153570A GB45816/66A GB4581666A GB1153570A GB 1153570 A GB1153570 A GB 1153570A GB 45816/66 A GB45816/66 A GB 45816/66A GB 4581666 A GB4581666 A GB 4581666A GB 1153570 A GB1153570 A GB 1153570A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- alkoxy
- amino
- radical
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002148 esters Chemical class 0.000 title abstract 2
- 125000001041 indolyl group Chemical group 0.000 title 1
- -1 aliphatic alcohols Chemical class 0.000 abstract 14
- 125000000217 alkyl group Chemical group 0.000 abstract 12
- 125000003545 alkoxy group Chemical group 0.000 abstract 6
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 4
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 4
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 abstract 2
- 230000002378 acidificating effect Effects 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000003282 alkyl amino group Chemical group 0.000 abstract 2
- 125000000304 alkynyl group Chemical group 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001188 haloalkyl group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 238000007327 hydrogenolysis reaction Methods 0.000 abstract 2
- 150000003254 radicals Chemical class 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 125000004214 1-pyrrolidinyl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- WZKSXHQDXQKIQJ-UHFFFAOYSA-N F[C](F)F Chemical compound F[C](F)F WZKSXHQDXQKIQJ-UHFFFAOYSA-N 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 125000000033 alkoxyamino group Chemical group 0.000 abstract 1
- 125000004947 alkyl aryl amino group Chemical group 0.000 abstract 1
- 125000002877 alkyl aryl group Chemical group 0.000 abstract 1
- 125000005248 alkyl aryloxy group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000005133 alkynyloxy group Chemical group 0.000 abstract 1
- 125000003368 amide group Chemical group 0.000 abstract 1
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000004659 aryl alkyl thio group Chemical group 0.000 abstract 1
- 125000002102 aryl alkyloxo group Chemical group 0.000 abstract 1
- 125000001769 aryl amino group Chemical group 0.000 abstract 1
- 125000005110 aryl thio group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 125000003739 carbamimidoyl group Chemical group C(N)(=N)* 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 125000000000 cycloalkoxy group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000004438 haloalkoxy group Chemical group 0.000 abstract 1
- 125000004995 haloalkylthio group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 150000002430 hydrocarbons Chemical class 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 abstract 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
- RQRAKXWAVSGUEZ-UHFFFAOYSA-N oxazireno[2,3-a]indole Chemical class O1c2cc3ccccc3n12 RQRAKXWAVSGUEZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229940067157 phenylhydrazine Drugs 0.000 abstract 1
- 150000004031 phenylhydrazines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- PXQLVRUNWNTZOS-UHFFFAOYSA-N sulfanyl Chemical class [SH] PXQLVRUNWNTZOS-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
- C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Joints Allowing Movement (AREA)
- Quick-Acting Or Multi-Walled Pipe Joints (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49670165A | 1965-10-15 | 1965-10-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1153570A true GB1153570A (en) | 1969-05-29 |
Family
ID=23973760
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB45816/66A Expired GB1153570A (en) | 1965-10-15 | 1966-10-13 | Indolyl Alkanol Esters |
Country Status (12)
| Country | Link |
|---|---|
| BE (1) | BE688252A (cs) |
| BR (1) | BR6683444D0 (cs) |
| CH (1) | CH476725A (cs) |
| DE (1) | DE1620042A1 (cs) |
| DK (1) | DK114833B (cs) |
| ES (1) | ES332606A1 (cs) |
| FR (2) | FR1502885A (cs) |
| GB (1) | GB1153570A (cs) |
| IL (1) | IL26624A (cs) |
| NL (2) | NL6614354A (cs) |
| NO (1) | NO121043B (cs) |
| SE (1) | SE321679B (cs) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5283251A (en) * | 1990-02-26 | 1994-02-01 | Fujisawa Pharmaceutical Co., Ltd. | Indole derivatives |
-
0
- NL NL130876D patent/NL130876C/xx active
-
1966
- 1966-10-03 IL IL2662466A patent/IL26624A/xx unknown
- 1966-10-03 FR FR78631A patent/FR1502885A/fr not_active Expired
- 1966-10-06 BR BR18344466A patent/BR6683444D0/pt unknown
- 1966-10-11 ES ES0332606A patent/ES332606A1/es not_active Expired
- 1966-10-12 NL NL6614354A patent/NL6614354A/xx unknown
- 1966-10-13 GB GB45816/66A patent/GB1153570A/en not_active Expired
- 1966-10-13 CH CH1477666A patent/CH476725A/de not_active IP Right Cessation
- 1966-10-14 BE BE688252D patent/BE688252A/xx unknown
- 1966-10-14 DK DK532166A patent/DK114833B/da unknown
- 1966-10-14 SE SE1398166A patent/SE321679B/xx unknown
- 1966-10-14 NO NO16514666A patent/NO121043B/no unknown
- 1966-10-14 DE DE19661620042 patent/DE1620042A1/de active Pending
-
1967
- 1967-01-02 FR FR89708A patent/FR6081M/fr not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5283251A (en) * | 1990-02-26 | 1994-02-01 | Fujisawa Pharmaceutical Co., Ltd. | Indole derivatives |
Also Published As
| Publication number | Publication date |
|---|---|
| BR6683444D0 (pt) | 1973-12-04 |
| NL130876C (cs) | |
| SE321679B (cs) | 1970-03-16 |
| FR6081M (cs) | 1968-06-04 |
| DE1620042A1 (de) | 1970-03-19 |
| ES332606A1 (es) | 1967-07-16 |
| FR1502885A (fr) | 1967-11-24 |
| IL26624A (en) | 1970-12-24 |
| CH476725A (de) | 1969-08-15 |
| BE688252A (cs) | 1967-04-14 |
| NO121043B (cs) | 1971-01-11 |
| DK114833B (da) | 1969-08-11 |
| NL6614354A (cs) | 1967-04-17 |
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