GB1147404A - Novel sulphonamide derivatives - Google Patents

Novel sulphonamide derivatives

Info

Publication number
GB1147404A
GB1147404A GB50520/68A GB5052068A GB1147404A GB 1147404 A GB1147404 A GB 1147404A GB 50520/68 A GB50520/68 A GB 50520/68A GB 5052068 A GB5052068 A GB 5052068A GB 1147404 A GB1147404 A GB 1147404A
Authority
GB
United Kingdom
Prior art keywords
substituted
halo
alkoxy
amino
sulphonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB50520/68A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Hoffmann La Roche Inc
Original Assignee
F Hoffmann La Roche AG
Hoffmann La Roche Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1136566A external-priority patent/CH500176A/en
Application filed by F Hoffmann La Roche AG, Hoffmann La Roche Inc filed Critical F Hoffmann La Roche AG
Publication of GB1147404A publication Critical patent/GB1147404A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52—Y being a hetero atom
    • C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
    • C07C311/57—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/59—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/28—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1,147,404. Sulphonamides. F. HOFFMANNLA ROCHE & CO. A.G. 4 Aug., 1967 [8 Aug., 1966], No. 50520/68. Divided out of 1,147,403. Heading C2C. Novel compounds of the general formula X.NH.CO.NH.SO 2 Y wherein X signifies a 2 - hydroxycyclohexyl or 2-hydroxycyclopentyl group which has been acylated at the hydroxy group with a sulphonyl carbamic acid, Y.SO 2 NH.CO 2 H, wherein Y represents a phenyl group which may be substituted by one or more amino, halo, alkyl, alkoxy, alkylthio, acyl, acylamino, diacylamido, alkoxy-substituted benzamido-ethyl, halo-substituted benzamido-ethyl and/or alkoxy-halo-substituted benzamidoethyl or Y represents a nitrogenlinked 5- or 6-membered nitrogen containing heterocycle, are obtained by reacting a sulphonyl carbamic acid derivative or a sulphonyl isocyanate with a 2-amino-cyclohexanol or 2-amino-cyclopentanol.
GB50520/68A 1966-08-08 1967-08-04 Novel sulphonamide derivatives Expired GB1147404A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH787469A CH509991A (en) 1966-08-08 1966-08-08 Sulphonamides and process for the manufacture thereof
CH787569A CH509992A (en) 1966-08-08 1966-08-08 Process for the preparation of sulfonamides
CH1136566A CH500176A (en) 1966-08-08 1966-08-08 Sulphonamides and process for the manufacture thereof

Publications (1)

Publication Number Publication Date
GB1147404A true GB1147404A (en) 1969-04-02

Family

ID=27175874

Family Applications (3)

Application Number Title Priority Date Filing Date
GB35845/67A Expired GB1147403A (en) 1966-08-08 1967-08-04 Sulphonamides
GB50521/68A Expired GB1147405A (en) 1966-08-08 1967-08-04 Novel oxazolidinone derivatives
GB50520/68A Expired GB1147404A (en) 1966-08-08 1967-08-04 Novel sulphonamide derivatives

Family Applications Before (2)

Application Number Title Priority Date Filing Date
GB35845/67A Expired GB1147403A (en) 1966-08-08 1967-08-04 Sulphonamides
GB50521/68A Expired GB1147405A (en) 1966-08-08 1967-08-04 Novel oxazolidinone derivatives

Country Status (11)

Country Link
JP (1) JPS5516575B1 (en)
BE (1) BE702280A (en)
CH (2) CH509992A (en)
DE (1) DE1668199B2 (en)
DK (1) DK122761B (en)
ES (1) ES343910A1 (en)
FR (1) FR7148M (en)
GB (3) GB1147403A (en)
IL (1) IL28401A (en)
NL (1) NL6710676A (en)
SE (1) SE334354B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10538487B2 (en) 2015-02-16 2020-01-21 The University Of Queensland Sulfonylureas and related compounds and use of same
US11840543B2 (en) 2017-05-24 2023-12-12 The University Of Queensland Compounds and uses
HRP20220195T1 (en) 2017-07-07 2022-04-15 Inflazome Limited Novel sulfonamide carboxamide compounds

Also Published As

Publication number Publication date
SE334354B (en) 1971-04-26
JPS5516575B1 (en) 1980-05-02
ES343910A1 (en) 1968-10-01
GB1147405A (en) 1969-04-02
GB1147403A (en) 1969-04-02
CH509992A (en) 1971-07-15
CH509991A (en) 1971-07-15
DK122761B (en) 1972-04-10
IL28401A (en) 1971-04-28
NL6710676A (en) 1968-02-09
DE1668199B2 (en) 1976-06-24
FR7148M (en) 1969-08-04
BE702280A (en) 1968-02-05
DE1668199A1 (en) 1971-09-02

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