GB1146448A - Oxime and conversion to primary amine - Google Patents

Oxime and conversion to primary amine

Info

Publication number
GB1146448A
GB1146448A GB2453366A GB2453366A GB1146448A GB 1146448 A GB1146448 A GB 1146448A GB 2453366 A GB2453366 A GB 2453366A GB 2453366 A GB2453366 A GB 2453366A GB 1146448 A GB1146448 A GB 1146448A
Authority
GB
United Kingdom
Prior art keywords
oxime
isoxazole
conversion
june
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2453366A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JR Geigy AG filed Critical JR Geigy AG
Publication of GB1146448A publication Critical patent/GB1146448A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/12—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

1,146,448. Isoxazole derivatives. J. R. GEIGY A.G. 2 June, 1966 [3 June, 1965], No. 24533/66. Heading C2C. 3 - Hydroxy - 5 - isoxazole carboxaldehyde oxime is prepared by converting 3-benzyloxy- 5-isoxazole carboxaldehyde into its oxime and treating the latter with catalytically activated hydrogen until substantially the equimolar amount is taken up. The product is converted into 3-hydroxy-5-aminomethylisoxazole and acid addition salts thereof by reduction, optionally followed by salt formation. The preparation of the starting material is described. Reference has been directed by the Comptroller to Specification 1,034,939.
GB2453366A 1965-06-03 1966-06-02 Oxime and conversion to primary amine Expired GB1146448A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH788165A CH450423A (en) 1965-06-03 1965-06-03 Process for the preparation of 3-hydroxy-5-aminomethyl-isoxazole

Publications (1)

Publication Number Publication Date
GB1146448A true GB1146448A (en) 1969-03-26

Family

ID=4331827

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2453366A Expired GB1146448A (en) 1965-06-03 1966-06-02 Oxime and conversion to primary amine

Country Status (7)

Country Link
AT (2) AT258901B (en)
BE (1) BE682009A (en)
CH (1) CH450423A (en)
ES (1) ES327480A1 (en)
FR (1) FR1481780A (en)
GB (1) GB1146448A (en)
NL (1) NL6607677A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5273989A (en) * 1990-04-12 1993-12-28 Hoechst Aktiengesellschaft 3,5-disubstituted 2-isoxazolines and isoxazoles, agents containing them and their use

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5273989A (en) * 1990-04-12 1993-12-28 Hoechst Aktiengesellschaft 3,5-disubstituted 2-isoxazolines and isoxazoles, agents containing them and their use

Also Published As

Publication number Publication date
BE682009A (en) 1966-12-02
AT263000B (en) 1968-07-10
CH450423A (en) 1968-01-31
AT258901B (en) 1967-12-27
NL6607677A (en) 1966-12-05
FR1481780A (en) 1967-05-19
ES327480A1 (en) 1967-07-16

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