GB1139097A - Process for producing 5'-purine nucleotides - Google Patents

Process for producing 5'-purine nucleotides

Info

Publication number
GB1139097A
GB1139097A GB2155966A GB2155966A GB1139097A GB 1139097 A GB1139097 A GB 1139097A GB 2155966 A GB2155966 A GB 2155966A GB 2155966 A GB2155966 A GB 2155966A GB 1139097 A GB1139097 A GB 1139097A
Authority
GB
United Kingdom
Prior art keywords
purine
micro
organism
purine nucleotides
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2155966A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Publication of GB1139097A publication Critical patent/GB1139097A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

1,139,097. 5<SP>1</SP>-Purine nucleotides. KYOWA HAKKO KOGYO CO. Ltd. 16 May, 1966 [18 May, 1965], No. 21559/66. Heading C2C. 5<SP>1</SP>-Purine nucleotides are prepared by culturing a micro-organism in the presenoe of a purine base in an aqueous nutrient medium under aerobic conditions, the micro-organism being of a strain which is not a purine base-requiring mutant strain but has the characteristics of being capable of (1) producing at least one of the compounds ribose-5-phosphate and 5-phosphoribosyl-1-pyrophosphate outside the cell walls thereof and (2) secreting the enzymes 5-phosphoribose pyrophosphokinase and 5<SP>1</SP>-purine nucleotide pyrophosphorylase from the cells thereof and recovering the product. The preferred strains of micro-organism include bacteria such as Bacillus megaterium, Arthrobacter ureafaciens, Micrococcus glutamicus, Corynebacterium rathayi, Brevibacterium ammoniagenes and Micrococcus sodonensis, moulds such as Aspergillus oryzae, Aspergillus sojae, Eremothecium ashbyii and penicillium chrysogenum, yeasts such as Saccharomyces cerevisiae, Torula utilis and Schizosaccharomyces pombe and actinomycetes such as Streptomyces fradiae and Streptomyces griseus. Examples are given for the preparation of 5<SP>1</SP>-inosinic acid, 5<SP>1</SP>-guanylic acid and 5<SP>1</SP>-adenylic acid and sodium salts thereof.
GB2155966A 1965-05-18 1966-05-16 Process for producing 5'-purine nucleotides Expired GB1139097A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2877965 1965-05-18

Publications (1)

Publication Number Publication Date
GB1139097A true GB1139097A (en) 1969-01-08

Family

ID=12257873

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2155966A Expired GB1139097A (en) 1965-05-18 1966-05-16 Process for producing 5'-purine nucleotides

Country Status (2)

Country Link
DE (1) DE1517821A1 (en)
GB (1) GB1139097A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005095627A3 (en) * 2004-03-31 2006-03-02 Ajinomoto Kk Method for producing purine nucleosides and nucleotides by fermentation using bacterium belonging to the genus bacillus or escherichia

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005095627A3 (en) * 2004-03-31 2006-03-02 Ajinomoto Kk Method for producing purine nucleosides and nucleotides by fermentation using bacterium belonging to the genus bacillus or escherichia
US9012182B2 (en) 2004-03-31 2015-04-21 Ajinomoto Co., Inc. Method for producing purine nucleosides and nucleotides by fermentation using bacterium belonging to the genus Bacillus or Escherichia

Also Published As

Publication number Publication date
DE1517821A1 (en) 1970-05-21

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