GB1135560A - Steroid compounds and their preparation - Google Patents

Steroid compounds and their preparation

Info

Publication number
GB1135560A
GB1135560A GB749167A GB749167A GB1135560A GB 1135560 A GB1135560 A GB 1135560A GB 749167 A GB749167 A GB 749167A GB 749167 A GB749167 A GB 749167A GB 1135560 A GB1135560 A GB 1135560A
Authority
GB
United Kingdom
Prior art keywords
radical
feb
hydrogen atom
preparation
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB749167A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to GB749166A priority Critical patent/GB1174583A/en
Application filed by GD Searle LLC filed Critical GD Searle LLC
Priority to NL6701851A priority patent/NL6701851A/xx
Priority to DE19671619707 priority patent/DE1619707A1/en
Priority to BE693877D priority patent/BE693877A/xx
Priority to FR94330A priority patent/FR1510706A/en
Publication of GB1135560A publication Critical patent/GB1135560A/en
Priority to NL6903922A priority patent/NL6903922A/xx
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1,135,560. Steroids. G. D. SEARLE & CO. 16 Feb.. 1967 [18 Feb., 1966], No. 7491/67. Heading C2U. Novel compounds of the formula wherein R 3 represents 3 alkyl radicals, which are the same or different, R<SP>1</SP> is a hydrogen atom, or an hydroxyl or alkanoyloxy radical; R<SP>11</SP> is a hydrogen atom or a methyl radical; R<SP>111</SP> is an alkyl radical; X is a hydrogen or halogen atom; Z is a methylene, #-hydroxymethylene or carbonyl radical; the dotted lines in Ring A each represent an optional double bond; and the wavy line in the 16-position on the steroid nucleus signifies that the substituent represented by R<SP>11</SP> can be either the α - or #-configuration are obtained by contacting the corresponding 21- OH compound with a trialkylsilylating agent, e.g. trimethylchlorosilane, hexamethyldisilazane or bis-(trimethylsilyl)-acetamide.
GB749167A 1966-02-18 1967-01-30 Steroid compounds and their preparation Expired GB1135560A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
GB749166A GB1174583A (en) 1966-02-21 1966-02-21 Vaporisation and further chlorination of Chlorinated Residues
NL6701851A NL6701851A (en) 1966-02-21 1967-02-07
DE19671619707 DE1619707A1 (en) 1966-02-21 1967-02-09 Process for the evaporation of decomposable substances
BE693877D BE693877A (en) 1966-02-21 1967-02-09
FR94330A FR1510706A (en) 1966-02-21 1967-02-09 Process for vaporizing easily pyrolyzed substances
NL6903922A NL6903922A (en) 1966-02-21 1969-03-13

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52841066A 1966-02-18 1966-02-18

Publications (1)

Publication Number Publication Date
GB1135560A true GB1135560A (en) 1968-12-04

Family

ID=24105578

Family Applications (1)

Application Number Title Priority Date Filing Date
GB749167A Expired GB1135560A (en) 1966-02-18 1967-01-30 Steroid compounds and their preparation

Country Status (9)

Country Link
BE (1) BE694135A (en)
CH (1) CH507297A (en)
DE (1) DE1618853B2 (en)
DK (1) DK117897B (en)
FR (1) FR6117M (en)
GB (1) GB1135560A (en)
GR (1) GR36782B (en)
IL (1) IL27448A (en)
SE (1) SE331094B (en)

Also Published As

Publication number Publication date
BE694135A (en) 1967-08-16
SE331094B (en) 1970-12-14
GR36782B (en) 1969-03-10
DE1618853B2 (en) 1976-11-18
FR6117M (en) 1968-06-17
IL27448A (en) 1971-01-28
CH507297A (en) 1971-05-15
DE1618853A1 (en) 1971-02-25
DK117897B (en) 1970-06-15

Similar Documents

Publication Publication Date Title
GB1475795A (en) Steroid 21-thioesters
GB1087828A (en) Steroidal derivatives
GB1529416A (en) Preparation of 7-keto-steroids from 7-unsubstituted steroids
GB1135560A (en) Steroid compounds and their preparation
GB1190257A (en) Improvements in or relating to the Preparation of Aldehydes and Ketones
ES363997A1 (en) 3-silyl-ether steroids
GB1187660A (en) Fluoroformates of Steroid 17-beta-Ols
GB1130189A (en) Improvements in or relating to steroid intermediates and the production thereof
GB1128789A (en) 7ª‡-alkyl-5(10),9(11)-diene steroids
ES391857A1 (en) Steroid derivatives and the preparation thereof
GB1182283A (en) Process for the Manufacture of 15,16beta-Methylene-Steroids
GB1127165A (en) Preparation of 17ª‡-hydroxyalkyl steroids and of 17aª‡-hydroxyalkyl-d-homo-steroids
GB1366329A (en) Process for the manufacture of delta4-3-oxo-1alpha-methylsteroids
GB1260723A (en) Gonapentaene derivatives
GB1131445A (en) Novel steroids
ES415479A1 (en) Oxaprostaglandins
AU272685B2 (en) Derivatives of 6-methyl-9-fluoro-4, 6-pregnadiene 3, 20, dione steroids
FR1503504A (en) 15alpha and 15beta-methyl derivatives of hydrocortisone, prednisolone cortisone, prednisone and their esters
GB1153274A (en) Mono- and Diesters of 13beta-Alkyl-17alpha-Alkynylgon-4-ene-3beta,17beta-Diols
AU2974363A (en) Derivatives of 6-methyl-9-fluoro-4, 6-pregnadiene 3, 20, dione steroids
ES319114A1 (en) A procedure for preparing the 21-hydroxy steroids of the pregnan series esterified in the position 21. (Machine-translation by Google Translate, not legally binding)
CA747901A (en) Synthesis of steroids of the pregnane series
GB1007022A (en) Improvements in or relating to 12-acylamino-steroids and to the production thereof
GB1053037A (en)
GB1129992A (en) Steroidal 17-ketals