GB1130715A - Improvements in or relating to vaccines based on mycoplasma pneumoniae - Google Patents
Improvements in or relating to vaccines based on mycoplasma pneumoniaeInfo
- Publication number
- GB1130715A GB1130715A GB525066A GB525066A GB1130715A GB 1130715 A GB1130715 A GB 1130715A GB 525066 A GB525066 A GB 525066A GB 525066 A GB525066 A GB 525066A GB 1130715 A GB1130715 A GB 1130715A
- Authority
- GB
- United Kingdom
- Prior art keywords
- vaccine
- medium
- eaton
- organisms
- mycoplasma pneumoniae
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229960005486 vaccine Drugs 0.000 title abstract 10
- 241000202934 Mycoplasma pneumoniae Species 0.000 title abstract 3
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 4
- 239000002609 medium Substances 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 3
- 108010088751 Albumins Proteins 0.000 abstract 2
- 102000009027 Albumins Human genes 0.000 abstract 2
- 239000004475 Arginine Substances 0.000 abstract 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 abstract 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- 239000008121 dextrose Substances 0.000 abstract 2
- 239000012530 fluid Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 244000005700 microbiome Species 0.000 abstract 2
- 239000000243 solution Substances 0.000 abstract 2
- 239000000725 suspension Substances 0.000 abstract 2
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 abstract 1
- 239000012981 Hank's balanced salt solution Substances 0.000 abstract 1
- 241000282414 Homo sapiens Species 0.000 abstract 1
- 102000008100 Human Serum Albumin Human genes 0.000 abstract 1
- 108091006905 Human Serum Albumin Proteins 0.000 abstract 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 abstract 1
- 108090000942 Lactalbumin Proteins 0.000 abstract 1
- 102000004407 Lactalbumin Human genes 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 241000204003 Mycoplasmatales Species 0.000 abstract 1
- BAWFJGJZGIEFAR-NNYOXOHSSA-N NAD zwitterion Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP([O-])(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-N 0.000 abstract 1
- 108010058846 Ovalbumin Proteins 0.000 abstract 1
- 235000019483 Peanut oil Nutrition 0.000 abstract 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- DWAQJAXMDSEUJJ-UHFFFAOYSA-M Sodium bisulfite Chemical compound [Na+].OS([O-])=O DWAQJAXMDSEUJJ-UHFFFAOYSA-M 0.000 abstract 1
- LUXUAZKGQZPOBZ-SAXJAHGMSA-N [(3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (Z)-octadec-9-enoate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O LUXUAZKGQZPOBZ-SAXJAHGMSA-N 0.000 abstract 1
- 229940037003 alum Drugs 0.000 abstract 1
- 230000002238 attenuated effect Effects 0.000 abstract 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract 1
- 239000007975 buffered saline Substances 0.000 abstract 1
- 229940041514 candida albicans extract Drugs 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- UGMCXQCYOVCMTB-UHFFFAOYSA-K dihydroxy(stearato)aluminium Chemical compound CCCCCCCCCCCCCCCCCC(=O)O[Al](O)O UGMCXQCYOVCMTB-UHFFFAOYSA-K 0.000 abstract 1
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000000413 hydrolysate Substances 0.000 abstract 1
- 230000002779 inactivation Effects 0.000 abstract 1
- 238000011534 incubation Methods 0.000 abstract 1
- 239000002054 inoculum Substances 0.000 abstract 1
- 229940067606 lecithin Drugs 0.000 abstract 1
- 239000000787 lecithin Substances 0.000 abstract 1
- 235000010445 lecithin Nutrition 0.000 abstract 1
- 238000006386 neutralization reaction Methods 0.000 abstract 1
- 229940092253 ovalbumin Drugs 0.000 abstract 1
- 239000000312 peanut oil Substances 0.000 abstract 1
- 239000002953 phosphate buffered saline Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000003908 quality control method Methods 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
- 235000017557 sodium bicarbonate Nutrition 0.000 abstract 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 abstract 1
- 239000004289 sodium hydrogen sulphite Substances 0.000 abstract 1
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 abstract 1
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 abstract 1
- 229940033663 thimerosal Drugs 0.000 abstract 1
- 235000015112 vegetable and seed oil Nutrition 0.000 abstract 1
- 239000008158 vegetable oil Substances 0.000 abstract 1
- 239000012138 yeast extract Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0241—Mollicutes, e.g. Mycoplasma, Erysipelothrix
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43238665A | 1965-02-12 | 1965-02-12 | |
| US51746865A | 1965-12-29 | 1965-12-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1130715A true GB1130715A (en) | 1968-10-16 |
Family
ID=27029471
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB525066A Expired GB1130715A (en) | 1965-02-12 | 1966-02-07 | Improvements in or relating to vaccines based on mycoplasma pneumoniae |
Country Status (5)
| Country | Link |
|---|---|
| CH (1) | CH490496A (enrdf_load_stackoverflow) |
| DE (1) | DE1617612A1 (enrdf_load_stackoverflow) |
| FR (1) | FR5460M (enrdf_load_stackoverflow) |
| GB (1) | GB1130715A (enrdf_load_stackoverflow) |
| NL (1) | NL6601781A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110938560A (zh) * | 2019-11-19 | 2020-03-31 | 成都天邦生物制品有限公司 | 一种快速高效猪肺炎支原体培养基及其配制方法 |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA998632A (en) * | 1972-03-18 | 1976-10-19 | Rudolf Mauler | Medium for the cultivation of mycoplasms |
-
1966
- 1966-02-07 GB GB525066A patent/GB1130715A/en not_active Expired
- 1966-02-11 DE DE19661617612 patent/DE1617612A1/de active Pending
- 1966-02-11 NL NL6601781A patent/NL6601781A/xx unknown
- 1966-02-11 CH CH198366A patent/CH490496A/de not_active IP Right Cessation
- 1966-05-10 FR FR61032A patent/FR5460M/fr not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110938560A (zh) * | 2019-11-19 | 2020-03-31 | 成都天邦生物制品有限公司 | 一种快速高效猪肺炎支原体培养基及其配制方法 |
| CN110938560B (zh) * | 2019-11-19 | 2023-08-18 | 成都史纪生物制药有限公司 | 一种快速高效猪肺炎支原体培养基及其配制方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| NL6601781A (enrdf_load_stackoverflow) | 1966-08-15 |
| CH490496A (de) | 1970-05-15 |
| FR5460M (enrdf_load_stackoverflow) | 1967-10-16 |
| DE1617612A1 (de) | 1971-03-25 |
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