GB1120190A - Novel phenethyl amines and a process for the manufacture thereof - Google Patents
Novel phenethyl amines and a process for the manufacture thereofInfo
- Publication number
- GB1120190A GB1120190A GB55124/66A GB5512466A GB1120190A GB 1120190 A GB1120190 A GB 1120190A GB 55124/66 A GB55124/66 A GB 55124/66A GB 5512466 A GB5512466 A GB 5512466A GB 1120190 A GB1120190 A GB 1120190A
- Authority
- GB
- United Kingdom
- Prior art keywords
- general formula
- pharmaceutically acceptable
- acid addition
- acceptable acid
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- -1 phenethyl amines Chemical class 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- BHHGXPLMPWCGHP-UHFFFAOYSA-N Phenethylamine Chemical class NCCC1=CC=CC=C1 BHHGXPLMPWCGHP-UHFFFAOYSA-N 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- WEJRYKSUUFKMBC-UHFFFAOYSA-N 1-(4-chlorophenyl)propan-2-one Chemical compound CC(=O)CC1=CC=C(Cl)C=C1 WEJRYKSUUFKMBC-UHFFFAOYSA-N 0.000 abstract 1
- HXKKHQJGJAFBHI-UHFFFAOYSA-N 1-aminopropan-2-ol Chemical compound CC(O)CN HXKKHQJGJAFBHI-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 239000002830 appetite depressant Substances 0.000 abstract 1
- 239000012320 chlorinating reagent Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 abstract 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- UHZYTMXLRWXGPK-UHFFFAOYSA-N phosphorus pentachloride Chemical compound ClP(Cl)(Cl)(Cl)Cl UHZYTMXLRWXGPK-UHFFFAOYSA-N 0.000 abstract 1
- YBBRCQOCSYXUOC-UHFFFAOYSA-N sulfuryl dichloride Chemical compound ClS(Cl)(=O)=O YBBRCQOCSYXUOC-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1730965A CH483390A (de) | 1966-10-28 | 1966-10-28 | Verfahren zur Herstellung eines Phenäthylamins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1120190A true GB1120190A (en) | 1968-07-17 |
Family
ID=4424416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB55124/66A Expired GB1120190A (en) | 1966-10-28 | 1966-12-09 | Novel phenethyl amines and a process for the manufacture thereof |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3502724A (en:Method) |
| BE (1) | BE690935A (en:Method) |
| CH (1) | CH483390A (en:Method) |
| DE (1) | DE1543670A1 (en:Method) |
| ES (1) | ES334477A1 (en:Method) |
| FR (2) | FR6149M (en:Method) |
| GB (1) | GB1120190A (en:Method) |
| IL (1) | IL27001A (en:Method) |
| NL (1) | NL6616446A (en:Method) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3925363A (en) * | 1974-01-17 | 1975-12-09 | Merck & Co Inc | Process for epimerizing penicillin compounds, and related products |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1210873B (de) * | 1959-03-18 | 1966-02-17 | Hoffmann La Roche | Verfahren zur Herstellung von Halogenalkylaminen |
| US3320319A (en) * | 1961-03-29 | 1967-05-16 | Degussa | 1-(aryl)-2-methyl-2-aliphatic amino-propanes |
| US3215598A (en) * | 1961-10-16 | 1965-11-02 | Merck & Co Inc | Anorectic compositions and method of using same |
-
1966
- 1966-10-28 CH CH1730965A patent/CH483390A/de not_active IP Right Cessation
- 1966-10-31 DE DE19661543670 patent/DE1543670A1/de active Pending
- 1966-11-22 NL NL6616446A patent/NL6616446A/xx unknown
- 1966-11-25 US US596788A patent/US3502724A/en not_active Expired - Lifetime
- 1966-11-28 FR FR85147A patent/FR6149M/fr not_active Expired
- 1966-12-04 IL IL27001A patent/IL27001A/xx unknown
- 1966-12-08 FR FR86584A patent/FR1503418A/fr not_active Expired
- 1966-12-09 BE BE690935D patent/BE690935A/xx unknown
- 1966-12-09 GB GB55124/66A patent/GB1120190A/en not_active Expired
- 1966-12-13 ES ES334477A patent/ES334477A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR1503418A (fr) | 1967-11-24 |
| BE690935A (en:Method) | 1967-06-09 |
| ES334477A1 (es) | 1968-02-16 |
| US3502724A (en) | 1970-03-24 |
| NL6616446A (en:Method) | 1967-06-16 |
| FR6149M (en:Method) | 1968-07-01 |
| CH483390A (de) | 1969-12-31 |
| IL27001A (en) | 1971-01-28 |
| DE1543670A1 (de) | 1969-10-09 |
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