GB1115992A - Improvements in or relating to n-piperidino-alkoxyacetophenones - Google Patents
Improvements in or relating to n-piperidino-alkoxyacetophenonesInfo
- Publication number
- GB1115992A GB1115992A GB1298765A GB1298765A GB1115992A GB 1115992 A GB1115992 A GB 1115992A GB 1298765 A GB1298765 A GB 1298765A GB 1298765 A GB1298765 A GB 1298765A GB 1115992 A GB1115992 A GB 1115992A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkoxy
- precipitate
- alkyl
- reacting
- alkoxyacetophenones
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003839 salts Chemical class 0.000 abstract 4
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 231100000252 nontoxic Toxicity 0.000 abstract 2
- 230000003000 nontoxic effect Effects 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- VQTDPCRSXHFMOL-UHFFFAOYSA-N 2,4-Dimethoxyacetophenone Chemical compound COC1=CC=C(C(C)=O)C(OC)=C1 VQTDPCRSXHFMOL-UHFFFAOYSA-N 0.000 abstract 1
- UZOFELREXGAFOI-UHFFFAOYSA-N 4-methylpiperidine Chemical compound CC1CCNCC1 UZOFELREXGAFOI-UHFFFAOYSA-N 0.000 abstract 1
- KWOLFJPFCHCOCG-UHFFFAOYSA-N Acetophenone Natural products CC(=O)C1=CC=CC=C1 KWOLFJPFCHCOCG-UHFFFAOYSA-N 0.000 abstract 1
- 206010039897 Sedation Diseases 0.000 abstract 1
- 150000008062 acetophenones Chemical class 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000002921 anti-spasmodic effect Effects 0.000 abstract 1
- HNYOPLTXPVRDBG-UHFFFAOYSA-N barbituric acid Chemical compound O=C1CC(=O)NC(=O)N1 HNYOPLTXPVRDBG-UHFFFAOYSA-N 0.000 abstract 1
- 239000000812 cholinergic antagonist Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000001704 evaporation Methods 0.000 abstract 1
- 239000000706 filtrate Substances 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 238000007912 intraperitoneal administration Methods 0.000 abstract 1
- 150000003891 oxalate salts Chemical class 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- IMACFCSSMIZSPP-UHFFFAOYSA-N phenacyl chloride Chemical compound ClCC(=O)C1=CC=CC=C1 IMACFCSSMIZSPP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 230000036280 sedation Effects 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1298765A GB1115992A (en) | 1965-03-26 | 1965-03-26 | Improvements in or relating to n-piperidino-alkoxyacetophenones |
| FR55136A FR5229M (enrdf_load_stackoverflow) | 1965-03-26 | 1966-03-26 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1298765A GB1115992A (en) | 1965-03-26 | 1965-03-26 | Improvements in or relating to n-piperidino-alkoxyacetophenones |
| GB4486765 | 1965-10-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1115992A true GB1115992A (en) | 1968-06-06 |
Family
ID=26249398
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1298765A Expired GB1115992A (en) | 1965-03-26 | 1965-03-26 | Improvements in or relating to n-piperidino-alkoxyacetophenones |
Country Status (2)
| Country | Link |
|---|---|
| FR (1) | FR5229M (enrdf_load_stackoverflow) |
| GB (1) | GB1115992A (enrdf_load_stackoverflow) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5123492B1 (enrdf_load_stackoverflow) * | 1970-05-06 | 1976-07-17 | ||
| US4277474A (en) * | 1978-02-22 | 1981-07-07 | Nippon Zoki Pharmaceutical Co., Ltd. | Treatment of allergic symptoms with propanone derivatives |
| FR2534912A1 (fr) * | 1982-10-26 | 1984-04-27 | Lafon Labor | Nouveaux derives de (2,4,6-trimethoxyphenyl) - (3-piperidinopropyl) -cetone, utilisation en therapeutique et procede de preparation |
-
1965
- 1965-03-26 GB GB1298765A patent/GB1115992A/en not_active Expired
-
1966
- 1966-03-26 FR FR55136A patent/FR5229M/fr not_active Expired
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5123492B1 (enrdf_load_stackoverflow) * | 1970-05-06 | 1976-07-17 | ||
| US4277474A (en) * | 1978-02-22 | 1981-07-07 | Nippon Zoki Pharmaceutical Co., Ltd. | Treatment of allergic symptoms with propanone derivatives |
| FR2534912A1 (fr) * | 1982-10-26 | 1984-04-27 | Lafon Labor | Nouveaux derives de (2,4,6-trimethoxyphenyl) - (3-piperidinopropyl) -cetone, utilisation en therapeutique et procede de preparation |
| EP0110747A3 (en) * | 1982-10-26 | 1984-08-08 | Laboratoire L. Lafon Societe Anonyme Dite: | (2,4,6-trimethoxyphenyl)-(3-piperidinopropyl)-ketone derivatives, their therapeutical use and preparation process |
| US4705795A (en) * | 1982-10-26 | 1987-11-10 | Laboratoire L. Lafon | (2,4,6-trimethoxyphenyl)-(3-piperidinopropyl)-ketone derivatives |
Also Published As
| Publication number | Publication date |
|---|---|
| FR5229M (enrdf_load_stackoverflow) | 1967-07-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1367677A (en) | Optically active basically substituted phenylacetonitriles | |
| CA2079548A1 (en) | Carbamate derivatives of 4-amino-3- isoxazolidinones, 3-amino-1- hydroxypyrrolidin-2-ones and 1-amino-1- cyclopropanecarboxylic acid analogs, a process for their preparation and their use as medicaments | |
| GB1115992A (en) | Improvements in or relating to n-piperidino-alkoxyacetophenones | |
| GB1107470A (en) | Basic esters and a process for their production | |
| GB1436978A (en) | Choline derivatives and pharmaceutical compositions containing the same | |
| SE7511028L (sv) | Forfarande for framstellning av nya 2,6-disubstituerade 2-fenyliminoimidazolidiner, deras syraadditionssalter och lekemedel innehallande dessa | |
| GB1228736A (enrdf_load_stackoverflow) | ||
| GB1450211A (en) | 5-methylthiopyrimidines their preparation and use | |
| GB1390867A (en) | Quinoline derivatives | |
| GB1104145A (en) | Pyrazolo-pyridine derivatives | |
| US3002886A (en) | Betaine salicylates and the method for their preparation | |
| GB1341955A (en) | Aryl 4-piperidyl ketone derivatives | |
| GB1434580A (en) | Disubstituted piperazines | |
| GB1043519A (en) | New basic alcohols | |
| US3290290A (en) | Aliphatic keto penicillins | |
| GB1000422A (en) | Improvements in or relating to aromatic amides | |
| GB1384523A (en) | Oxime derivatives and their preparation | |
| GB1254270A (en) | Benzoxazepine derivatives | |
| GB1124838A (en) | Phenyl-propylamine derivatives and process for preparing them | |
| GB1333524A (en) | Penicilloic acid derivatives | |
| US2390593A (en) | Dicarboxylic acid derivatives of lower alkyl ethers of vitamin b6, and a process of peparing the same | |
| GB1425911A (en) | Phenylacetic acid derivatives, process for their preparation and therapeutic composition containing same | |
| IE36874B1 (en) | Thiazolino-pyrimidin-5-one derivatives process for their preparation and applications thereof | |
| GB1244481A (en) | Benzothiazine derivatives and the preparation thereof | |
| GB1371757A (en) | Substituted aminoquinolizinium bromides their preparation and compositions thereof |