GB1115327A - Dibenzocycloheptene derivatives - Google Patents

Dibenzocycloheptene derivatives

Info

Publication number
GB1115327A
GB1115327A GB5401565A GB5401565A GB1115327A GB 1115327 A GB1115327 A GB 1115327A GB 5401565 A GB5401565 A GB 5401565A GB 5401565 A GB5401565 A GB 5401565A GB 1115327 A GB1115327 A GB 1115327A
Authority
GB
United Kingdom
Prior art keywords
compounds
represent
alkyl
organic solvent
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5401565A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1115327A publication Critical patent/GB1115327A/en
Expired legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B27WORKING OR PRESERVING WOOD OR SIMILAR MATERIAL; NAILING OR STAPLING MACHINES IN GENERAL
    • B27BSAWS FOR WOOD OR SIMILAR MATERIAL; COMPONENTS OR ACCESSORIES THEREFOR
    • B27B33/00Sawing tools for saw mills, sawing machines, or sawing devices
    • B27B33/02Structural design of saw blades or saw teeth
    • B27B33/10Hand saw blades
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B23MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
    • B23DPLANING; SLOTTING; SHEARING; BROACHING; SAWING; FILING; SCRAPING; LIKE OPERATIONS FOR WORKING METAL BY REMOVING MATERIAL, NOT OTHERWISE PROVIDED FOR
    • B23D61/00Tools for sawing machines or sawing devices; Clamping devices for these tools
    • B23D61/12Straight saw blades; Strap saw blades
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Forests & Forestry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention comprises compounds of the formula <FORM:1115327/C2/1> (wherein X represents a hydrogen or halogen atom, or a C1- 5 alkyl, trifluoromethyl, C1- 5 alkoxy, C1- 5 alkylsulphonyl, C1- 5 alkylmercapto or di-(C1- 4 alkyl) sulphamoyl; each of R and R1 represents a hydrogen atom or a methyl group and the dotted line indicates that an optional double bond may be present in the 10-11 position) and non-toxic salts thereof, and their preparation, where R and R1 represent hydrogen atoms, by reducing the corresponding 5-cyanodibenzo[a,d]cycloheptene derivatives with lithium aluminium hydride in an inert organic solvent; where one of R and R1 represents a hydrogen atom, and the other a methyl group, by reducing the corresponding formylaminomethyl derivative with lithium aluminium hydride in an inert organic solvent or by dealkylation of those compounds of the above formula wherein both R and R1 represent methyl groups; and, where both R and R1 represent methyl groups, by reacting the corresponding compounds where R and R1 represent hydrogen atoms with formaldehyde and formic acid. Therapeutic compositions with anti-convulsive properties, which may be administered perorally or parenterally, comprise compounds of the above general formula or their non-toxic salts and a carrier therefor.
GB5401565A 1964-12-31 1965-12-21 Dibenzocycloheptene derivatives Expired GB1115327A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42248864A 1964-12-31 1964-12-31

Publications (1)

Publication Number Publication Date
GB1115327A true GB1115327A (en) 1968-05-29

Family

ID=23675113

Family Applications (2)

Application Number Title Priority Date Filing Date
GB5401565A Expired GB1115327A (en) 1964-12-31 1965-12-21 Dibenzocycloheptene derivatives
GB3179567A Expired GB1115329A (en) 1964-12-31 1965-12-21 Dibenzocycloheptene derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB3179567A Expired GB1115329A (en) 1964-12-31 1965-12-21 Dibenzocycloheptene derivatives

Country Status (13)

Country Link
JP (2) JPS518948B1 (en)
BE (1) BE674493A (en)
BR (1) BR6575868D0 (en)
CH (2) CH492671A (en)
DE (2) DE1793549A1 (en)
DK (1) DK134010B (en)
ES (1) ES321390A1 (en)
FR (2) FR1481056A (en)
GB (2) GB1115327A (en)
IL (1) IL24802A (en)
NL (1) NL148587B (en)
NO (1) NO119796B (en)
SE (2) SE347739B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL161432C (en) * 1968-01-30 1980-02-15 Merck & Co Inc METHOD FOR THE PREPARATION OF PHARMACEUTICAL PREPARATIONS, THE FORMED PHARMACEUTICAL PREPARATIONS OBTAINED BY THEIR USE AND METHOD FOR THE PREPARATION OF POLYHYDRODIBENZOA,D-CYCLOALKENE DERIVATIVES.
JPS54115360U (en) * 1978-01-31 1979-08-13

Also Published As

Publication number Publication date
CH461477A (en) 1968-08-31
IL24802A (en) 1969-05-28
FR1481056A (en) 1967-05-19
SE347739B (en) 1972-08-14
NL148587B (en) 1976-02-16
DK134010B (en) 1976-08-30
BR6575868D0 (en) 1973-09-06
FR5669M (en) 1968-01-02
NO119796B (en) 1970-07-06
GB1115329A (en) 1968-05-29
DK134010C (en) 1977-02-07
SE322771B (en) 1970-04-20
JPS518947B1 (en) 1976-03-22
DE1793549A1 (en) 1972-03-02
CH492671A (en) 1970-06-30
DE1543261A1 (en) 1969-09-11
NL6517264A (en) 1966-07-04
JPS518948B1 (en) 1976-03-22
ES321390A1 (en) 1966-06-16
BE674493A (en) 1966-06-29

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