GB1113227A - Adamantanecarboxylic acid derivatives - Google Patents

Adamantanecarboxylic acid derivatives

Info

Publication number
GB1113227A
GB1113227A GB2618766A GB2618766A GB1113227A GB 1113227 A GB1113227 A GB 1113227A GB 2618766 A GB2618766 A GB 2618766A GB 2618766 A GB2618766 A GB 2618766A GB 1113227 A GB1113227 A GB 1113227A
Authority
GB
United Kingdom
Prior art keywords
homoadamantane
adamantane
nrr
alk
radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2618766A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Priority to US561707A priority Critical patent/US3374244A/en
Priority to US644099A priority patent/US3565942A/en
Publication of GB1113227A publication Critical patent/GB1113227A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/12Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group, wherein Cn means a carbon skeleton not containing a ring; Thio analogues thereof

Abstract

1,113,227. Derivatives of adamantane and homoadamantane. G. D. SEARLE & CO. 13 June, 1966 [24 June, 1965 (2)], No. 26187/66. Heading C2C. Novel compounds of formula wherein A is an adamantyl or homoadamantyl radical which is linked to the adjacent carbonyl function at a bridgehead position, X is an oxygen or sulphur atom or the group -NH-, Alk is an alkylene radical containing 2 to 8 carbon atoms, and -NRR<SP>1</SP> is a dialkylamino radical wherein the alkyl groups each contain 1 to 6 carbon atoms, or a 1-pyrrolidinyl, piperidino, morpholino or 4-methyl-1-piperazinyl radical, and the acid addition and quaternary ammonium salts thereof, are prepared by reacting an adamantane- or homoadamantane-carboxylic acid halide with a compound of formula HX-Alk-NRR<SP>1</SP>, or, when X is an oxygen atom, by reacting an adamantane- or homoadamantane-carboxylic acid with a halide of formula Halogen-Alk- NRR<SP>1</SP> in an alkanol solvent. Adamantane- or homoadamantane-carboxylic acid chloride is obtained by treating the corresponding acid with thionyl chloride.
GB2618766A 1965-06-24 1966-06-13 Adamantanecarboxylic acid derivatives Expired GB1113227A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US561707A US3374244A (en) 1966-06-13 1966-06-30 N-(dialkylaminoalkyl)adamantanecarboxamides and related compounds
US644099A US3565942A (en) 1966-06-13 1967-06-07 Dialkylaminoalkyl esters of adamantanecarboxylic acids

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46683265A 1965-06-24 1965-06-24
US46681265A 1965-06-24 1965-06-24
FR144289 1968-03-18

Publications (1)

Publication Number Publication Date
GB1113227A true GB1113227A (en) 1968-05-08

Family

ID=31950288

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2618766A Expired GB1113227A (en) 1965-06-24 1966-06-13 Adamantanecarboxylic acid derivatives

Country Status (2)

Country Link
FR (1) FR1556794A (en)
GB (1) GB1113227A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7003946A (en) * 1969-03-26 1970-09-29

Also Published As

Publication number Publication date
FR1556794A (en) 1969-02-07

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