GB1111905A - Alkyl-substituted 5-trifluoromethyl-6-amino-benzimidazoles - Google Patents
Alkyl-substituted 5-trifluoromethyl-6-amino-benzimidazolesInfo
- Publication number
- GB1111905A GB1111905A GB2339466A GB2339466A GB1111905A GB 1111905 A GB1111905 A GB 1111905A GB 2339466 A GB2339466 A GB 2339466A GB 2339466 A GB2339466 A GB 2339466A GB 1111905 A GB1111905 A GB 1111905A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- benzimidazoles
- trifluoromethyl
- amino
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- VJJPUDRRXWUOON-UHFFFAOYSA-N 6-(trifluoromethyl)-1H-benzimidazol-5-amine Chemical class Nc1cc2nc[nH]c2cc1C(F)(F)F VJJPUDRRXWUOON-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N Aniline Chemical compound NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 abstract 2
- 239000003638 chemical reducing agent Substances 0.000 abstract 2
- LQNUZADURLCDLV-UHFFFAOYSA-N nitrobenzene Chemical compound [O-][N+](=O)C1=CC=CC=C1 LQNUZADURLCDLV-UHFFFAOYSA-N 0.000 abstract 2
- 230000000802 nitrating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention comprises compound of the general formula <FORM:1111905/C2/1> wherein R and R1 are the same or different and are C1- 6 alkyl radicals. The compounds are prepared by nitrating a compound of the general formula <FORM:1111905/C2/2> to give a compound of the formula <FORM:1111905/C2/3> which is then reduced to the desired product using a reducing agent which will reduce using a reducing agent which will reduce nitrobenzene to aniline.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2339466A GB1111905A (en) | 1965-06-03 | 1965-06-03 | Alkyl-substituted 5-trifluoromethyl-6-amino-benzimidazoles |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2339466A GB1111905A (en) | 1965-06-03 | 1965-06-03 | Alkyl-substituted 5-trifluoromethyl-6-amino-benzimidazoles |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1111905A true GB1111905A (en) | 1968-05-01 |
Family
ID=10194903
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2339466A Expired GB1111905A (en) | 1965-06-03 | 1965-06-03 | Alkyl-substituted 5-trifluoromethyl-6-amino-benzimidazoles |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB1111905A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2234287A1 (en) * | 1973-02-20 | 1975-01-17 | United States Borax Chem | |
US3901910A (en) * | 1973-02-20 | 1975-08-26 | United States Borax Chem | 5-trifluoromethyl-7-aminobenzimidazoles |
US3987182A (en) * | 1974-06-17 | 1976-10-19 | Schering Corporation | Novel benzimidazoles useful as anti-androgens |
-
1965
- 1965-06-03 GB GB2339466A patent/GB1111905A/en not_active Expired
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2234287A1 (en) * | 1973-02-20 | 1975-01-17 | United States Borax Chem | |
US3901910A (en) * | 1973-02-20 | 1975-08-26 | United States Borax Chem | 5-trifluoromethyl-7-aminobenzimidazoles |
US3987182A (en) * | 1974-06-17 | 1976-10-19 | Schering Corporation | Novel benzimidazoles useful as anti-androgens |
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