GB1098804A - Novel benzylmercaptans - Google Patents

Novel benzylmercaptans

Info

Publication number
GB1098804A
GB1098804A GB17435/67A GB1743567A GB1098804A GB 1098804 A GB1098804 A GB 1098804A GB 17435/67 A GB17435/67 A GB 17435/67A GB 1743567 A GB1743567 A GB 1743567A GB 1098804 A GB1098804 A GB 1098804A
Authority
GB
United Kingdom
Prior art keywords
benzylmercaptans
novel
formula
phenyl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB17435/67A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US445248A external-priority patent/US3346638A/en
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB1098804A publication Critical patent/GB1098804A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/18—Eight-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/18—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Compounds of the general formula <FORM:1098804/C2/1> (wherein R1 represents a halogen atom or a C1- 7 alkyl or alkoxy group, R2 represents a phenyl or halophenyl group and the broken line denotes an optional substituent) are prepared by treating a compound of the formula <FORM:1098804/C2/2> with an aqueous-alkaline medium.
GB17435/67A 1963-03-18 1966-03-31 Novel benzylmercaptans Expired GB1098804A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US26603063A 1963-03-18 1963-03-18
US44526465A 1965-04-02 1965-04-02
US445248A US3346638A (en) 1965-04-02 1965-04-02 Alpha-phenyl-2-amino-benzylmercaptanes
US535722A US3400119A (en) 1963-03-18 1966-03-21 Novel 4, 1-benzothiazepin-2(1h)-ones and 4, 1-benzothiazepines

Publications (1)

Publication Number Publication Date
GB1098804A true GB1098804A (en) 1968-01-10

Family

ID=27500875

Family Applications (8)

Application Number Title Priority Date Filing Date
GB11161/64A Expired GB1043481A (en) 1963-03-18 1964-03-17 Thiaza heterocyclics and the manufacture thereof
GB17435/67A Expired GB1098804A (en) 1963-03-18 1966-03-31 Novel benzylmercaptans
GB14251/66A Expired GB1098803A (en) 1963-03-18 1966-03-31 A process for the manufacture of benzthiaz[4,1]epine derivatives
GB9997/67A Expired GB1077276A (en) 1963-03-18 1966-03-31 Novel thiaza heterocyclics
GB17437/67A Expired GB1098806A (en) 1963-03-18 1966-03-31 Novel benzoxazinethiones
GB14252/66A Expired GB1077272A (en) 1963-03-18 1966-03-31 Novel thiaza heterocyclics and a process for the manufacture thereof
GB17438/67A Expired GB1098807A (en) 1963-03-18 1966-03-31 Novel benzothiazinethiones
GB17436/67A Expired GB1098805A (en) 1963-03-18 1966-03-31 Novel benzothiazinones

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB11161/64A Expired GB1043481A (en) 1963-03-18 1964-03-17 Thiaza heterocyclics and the manufacture thereof

Family Applications After (6)

Application Number Title Priority Date Filing Date
GB14251/66A Expired GB1098803A (en) 1963-03-18 1966-03-31 A process for the manufacture of benzthiaz[4,1]epine derivatives
GB9997/67A Expired GB1077276A (en) 1963-03-18 1966-03-31 Novel thiaza heterocyclics
GB17437/67A Expired GB1098806A (en) 1963-03-18 1966-03-31 Novel benzoxazinethiones
GB14252/66A Expired GB1077272A (en) 1963-03-18 1966-03-31 Novel thiaza heterocyclics and a process for the manufacture thereof
GB17438/67A Expired GB1098807A (en) 1963-03-18 1966-03-31 Novel benzothiazinethiones
GB17436/67A Expired GB1098805A (en) 1963-03-18 1966-03-31 Novel benzothiazinones

Country Status (13)

Country Link
US (1) US3400119A (en)
BE (3) BE645242A (en)
BR (3) BR6457097D0 (en)
CH (7) CH441327A (en)
DE (3) DE1445889A1 (en)
DK (2) DK126383B (en)
FR (3) FR3681M (en)
GB (8) GB1043481A (en)
IL (4) IL33556A (en)
MY (2) MY6800087A (en)
NL (3) NL139179B (en)
NO (1) NO121211B (en)
SE (2) SE345670B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3463774A (en) * 1963-03-18 1969-08-26 Hoffmann La Roche Novel 4,1-benzothiazepin-2-(1h)-ones and 4,1-benzothiazepines
US3485824A (en) * 1963-03-18 1969-12-23 Hoffmann La Roche 1-substituted 4,1-benzothiazepin-2(1h)-ones and 4,1-benzothiazepines
BE686793A (en) * 1965-09-15 1967-03-13
US3542767A (en) * 1968-02-29 1970-11-24 American Home Prod Substituted 1,3,4-benzotriazepin-5h-5-ones
US3539555A (en) * 1968-12-12 1970-11-10 Squibb & Sons Inc Dibenzo(b,f)(1,4)oxazocines,dibenzo(b,f)(1,4)oxazonines and thio analogs
US3682962A (en) * 1970-03-17 1972-08-08 Sterling Drug Inc 1-substituted-1,2,3,5-tetrahydro-4,1-benzothiozepines
US3697516A (en) * 1970-10-19 1972-10-10 Phillips Petroleum Co Certain thiazine-2-thione compounds and method of preparing same
DE3320746A1 (en) * 1982-06-17 1983-12-22 Sandoz-Patent-GmbH, 7850 Lörrach BENZENE DERIVATIVES, THEIR PRODUCTION AND PHARMACEUTICAL PREPARATIONS WHICH THEY CONTAIN
US5246791A (en) * 1988-07-06 1993-09-21 Johnson Matthey Public Limited Company Fuel cell containing a reforming catalyst
CA2016517C (en) * 1989-05-11 1999-01-12 Dale R. Shackle Solid state electrochemical cell having microroughened current collector
AU678503B2 (en) * 1993-09-24 1997-05-29 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds and their use as squalene synthetase inhibitors
DE19924668A1 (en) 1999-05-28 2000-11-30 Bayer Ag Substituted alpha-phenyl-beta-ketosulfones
WO2015120059A1 (en) * 2014-02-04 2015-08-13 Yates Charles Ryan Inhibitors of paxillin function and related compositions and methods

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3144439A (en) * 1964-08-11 Process for production of benzo-
US3155649A (en) * 1962-07-11 1964-11-03 Olin Mathieson Benzothiazocinones, related compounds and their preparation

Also Published As

Publication number Publication date
MY6800087A (en) 1968-12-31
NL6604470A (en) 1966-10-03
IL25425A (en) 1970-07-19
US3400119A (en) 1968-09-03
SE345670B (en) 1972-06-05
FR3681M (en) 1965-11-15
NL6402756A (en) 1964-09-21
CH448096A (en) 1967-12-15
BE678771A (en) 1966-09-30
CH441327A (en) 1967-08-15
NL139179B (en) 1973-06-15
BE678772A (en) 1966-09-30
NO121211B (en) 1971-02-01
DK116362B (en) 1970-01-05
MY6800086A (en) 1968-12-31
GB1077272A (en) 1967-07-26
DE1695134A1 (en) 1970-12-10
IL33557A (en) 1970-07-19
GB1077276A (en) 1967-07-26
NL6604383A (en) 1966-10-03
FR5746M (en) 1968-01-29
CH441326A (en) 1967-08-15
GB1098806A (en) 1968-01-10
CH481131A (en) 1969-11-15
GB1098805A (en) 1968-01-10
DE1695132A1 (en) 1970-12-10
IL33556A (en) 1970-07-19
SE356983B (en) 1973-06-12
BE645242A (en) 1964-09-16
BR6678152D0 (en) 1973-09-06
DK126383B (en) 1973-07-09
BR6457097D0 (en) 1973-08-09
DE1445889A1 (en) 1969-04-10
FR5314M (en) 1967-08-21
BR6678325D0 (en) 1973-09-18
GB1043481A (en) 1966-09-21
IL25447A (en) 1970-06-17
GB1098803A (en) 1968-01-10
CH471809A (en) 1969-04-30
CH442313A (en) 1967-08-31
CH441324A (en) 1967-08-15
GB1098807A (en) 1968-01-10

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