GB1098416A - Medicaments comprising biocidal amino acids - Google Patents

Medicaments comprising biocidal amino acids

Info

Publication number
GB1098416A
GB1098416A GB14126/65A GB1412665A GB1098416A GB 1098416 A GB1098416 A GB 1098416A GB 14126/65 A GB14126/65 A GB 14126/65A GB 1412665 A GB1412665 A GB 1412665A GB 1098416 A GB1098416 A GB 1098416A
Authority
GB
United Kingdom
Prior art keywords
acid
amino
biocidal
benzyl
hydroxybenzoic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB14126/65A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of GB1098416A publication Critical patent/GB1098416A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)

Abstract

Pharmaceutical compositions in the form of emulsions or suspensions comprise one of the biocidal or biostatic substances:-p-chlorobenzyl alcohol, o-benzyl-p-chlorophenol, p-chloro-m-cresol, sodium o-phenyl phenolate, o-phenyl phenol, o-benzyl phenol, the benzyl, methyl, and methyl esters of p-hydroxybenzoic acid, the sodium salt of p-hydroxybenzoic acid propyl ester, 2,21-dihydroxy-5,51-dichlorodiphenyl methane, undecylenic acid, polymyxin B, neomycin sulphate, hydrocortisone or dexamethasone, and as the emulsion or suspension stabilizer, at least one amphoteric biocidal amino acid surfactant, which is characterized by having an aliphatic group containing at least 6 C atoms, at least one basic N atom, and at least one carboxyl group. Specified amino acids include N-hexadecyl glycine, N-(3-dodecylaminopropyl) - b - aminobutyric acid, and 3,5 - bis{{{2[2 - dodecylaminoethyl)amino]-ethyl}amino}methyl} salicylic acid.ALSO:A pharmaceutical preparation for topical application in the form of an emulsion or suspension comprises (1) one of the biocidal or biostatic substances:- p-chlorobenzyl alcohol, o-benzyl-p-chlorophenol, p-chloro-m-cresol, sodium-o-phenyl phenolate, o-phenyl phenol, o-benzyl phenol, p-hydroxybenzoic acid benzylester, p-hydroxybenzoic acid methylester, p-hydroxybenzoic acid propylester, the sodium salt of p-hydroxybenzoic acid propylester, 2,2\sv - dihydroxy - 5,5\sv - dichlorodiphenyl methane, undecylenic acid, polymyxin B, neomycin sulphate, hydrocortisone, or dexamethasone and (2) as the emulsion or suspension stabilizer, at least one biocidal amino-acid which is characterised by containing an aliphatic group having at least 6 carbon atoms, at least one basic N atom and at least one carboxyl group, or a salt thereof. Specified amino-acids include N-hexadecyl glycine, 3,5-bis[2\sT (2-dodecylaminoethyl)amino \sVethyl amino methyl] salicylic acid, and N-(3-dodecylaminopropyl)-b -aminobutyric acid. The preparations, which may be in the form of lotions or ointments, may be used in the treatment of bacterial or fungal skin diseases.
GB14126/65A 1965-02-04 1965-04-02 Medicaments comprising biocidal amino acids Expired GB1098416A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT98665A AT264013B (en) 1965-02-04 1965-02-04 Process for the production of emulsions or suspensions containing biocidal substances

Publications (1)

Publication Number Publication Date
GB1098416A true GB1098416A (en) 1968-01-10

Family

ID=3504315

Family Applications (1)

Application Number Title Priority Date Filing Date
GB14126/65A Expired GB1098416A (en) 1965-02-04 1965-04-02 Medicaments comprising biocidal amino acids

Country Status (2)

Country Link
AT (1) AT264013B (en)
GB (1) GB1098416A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932607A (en) * 1972-07-31 1976-01-13 Hesselgren Sven Gunnar Antimicrobial composition
US4062937A (en) * 1976-03-12 1977-12-13 La Verne Rea Insect bite relief preparation
US4582649A (en) * 1984-11-28 1986-04-15 Sandoz Ltd. Phenolamines
GB2302807A (en) * 1995-07-04 1997-02-05 Surtech Int Ltd Method and composition for treating atopic eczema
CN113303329A (en) * 2021-05-25 2021-08-27 中山市迈微环保科技有限公司 Disinfectant containing o-phenylphenol, preparation method and application thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932607A (en) * 1972-07-31 1976-01-13 Hesselgren Sven Gunnar Antimicrobial composition
US4062937A (en) * 1976-03-12 1977-12-13 La Verne Rea Insect bite relief preparation
US4582649A (en) * 1984-11-28 1986-04-15 Sandoz Ltd. Phenolamines
GB2302807A (en) * 1995-07-04 1997-02-05 Surtech Int Ltd Method and composition for treating atopic eczema
CN113303329A (en) * 2021-05-25 2021-08-27 中山市迈微环保科技有限公司 Disinfectant containing o-phenylphenol, preparation method and application thereof

Also Published As

Publication number Publication date
AT264013B (en) 1968-08-12

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