GB1091089A - Organic base salts of n-carbamyl-aspartic acids - Google Patents
Organic base salts of n-carbamyl-aspartic acidsInfo
- Publication number
- GB1091089A GB1091089A GB3590165A GB3590165A GB1091089A GB 1091089 A GB1091089 A GB 1091089A GB 3590165 A GB3590165 A GB 3590165A GB 3590165 A GB3590165 A GB 3590165A GB 1091089 A GB1091089 A GB 1091089A
- Authority
- GB
- United Kingdom
- Prior art keywords
- carbamyl
- organic base
- base salts
- aspartic acids
- aspartic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/06—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
- C07C275/16—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by carboxyl groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention comprises as novel compounds the organic base salts of N-carbamyl-dl and l-aspartic acids which are prepared by salifying the acid with the appropriate base. Suitable bases mentioned are morpholine, methyl-glucamine, amphetamine, pyridoxine, choline, lysine, arginine, ornithine, piperazine, dimethylaminoethanol and di-isopropylamine. Therapeutic compositions which have a hepatotropic effect and other activity and which may be administered orally, parenterally or rectally, comprise an organic base salt of N-carbamyl-dl or l-aspartic acid as active ingredient.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3590165A GB1091089A (en) | 1965-08-20 | 1965-08-20 | Organic base salts of n-carbamyl-aspartic acids |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3590165A GB1091089A (en) | 1965-08-20 | 1965-08-20 | Organic base salts of n-carbamyl-aspartic acids |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1091089A true GB1091089A (en) | 1967-11-15 |
Family
ID=10382802
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB3590165A Expired GB1091089A (en) | 1965-08-20 | 1965-08-20 | Organic base salts of n-carbamyl-aspartic acids |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB1091089A (en) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4447366A (en) * | 1980-12-04 | 1984-05-08 | Morelle Jean V | Derivatives of lysine and aspartic acid |
WO2002072534A2 (en) * | 2001-03-13 | 2002-09-19 | Erich Eigenbrodt | 1-butane acid derivatives, pharmaceutical compositions containing said derivatives and the use thereof |
WO2002072527A2 (en) * | 2001-03-13 | 2002-09-19 | Protagen Aktiengesellschaft | 1-butyric acid derivatives such as carbomethoxypropionyl cyanide or leflunomide derivatives, and the therapeutic use thereof |
US7655630B2 (en) | 2002-02-22 | 2010-02-02 | Shire Llc | Abuse-resistant amphetamine prodrugs |
US7659253B2 (en) | 2002-02-22 | 2010-02-09 | Shire Llc | Abuse-resistant amphetamine prodrugs |
US7662787B2 (en) | 2003-05-29 | 2010-02-16 | Shire Llc | Abuse resistant lysine amphetamine compounds |
US8106016B2 (en) | 2003-09-30 | 2012-01-31 | Shire Llc | Compounds and compositions for prevention of overdose of oxycodone |
US8394813B2 (en) | 2000-11-14 | 2013-03-12 | Shire Llc | Active agent delivery systems and methods for protecting and administering active agents |
-
1965
- 1965-08-20 GB GB3590165A patent/GB1091089A/en not_active Expired
Cited By (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4447366A (en) * | 1980-12-04 | 1984-05-08 | Morelle Jean V | Derivatives of lysine and aspartic acid |
US8394813B2 (en) | 2000-11-14 | 2013-03-12 | Shire Llc | Active agent delivery systems and methods for protecting and administering active agents |
WO2002072534A2 (en) * | 2001-03-13 | 2002-09-19 | Erich Eigenbrodt | 1-butane acid derivatives, pharmaceutical compositions containing said derivatives and the use thereof |
WO2002072527A2 (en) * | 2001-03-13 | 2002-09-19 | Protagen Aktiengesellschaft | 1-butyric acid derivatives such as carbomethoxypropionyl cyanide or leflunomide derivatives, and the therapeutic use thereof |
WO2002072527A3 (en) * | 2001-03-13 | 2003-01-16 | Stefan Muellner | 1-butyric acid derivatives such as carbomethoxypropionyl cyanide or leflunomide derivatives, and the therapeutic use thereof |
WO2002072534A3 (en) * | 2001-03-13 | 2003-08-28 | Erich Eigenbrodt | 1-butane acid derivatives, pharmaceutical compositions containing said derivatives and the use thereof |
US7671030B2 (en) | 2002-02-22 | 2010-03-02 | Shire Llc | Abuse-resistant amphetamine prodrugs |
US7687466B2 (en) | 2002-02-22 | 2010-03-30 | Shire Llc | Abuse-resistant amphetamine prodrugs |
US7655630B2 (en) | 2002-02-22 | 2010-02-02 | Shire Llc | Abuse-resistant amphetamine prodrugs |
US7662788B2 (en) | 2002-02-22 | 2010-02-16 | Shire Llc | Abuse-resistant amphetamine prodrugs |
US7659253B2 (en) | 2002-02-22 | 2010-02-09 | Shire Llc | Abuse-resistant amphetamine prodrugs |
US7671031B2 (en) | 2002-02-22 | 2010-03-02 | Shire Llc | Abuse-resistant amphetamine prodrugs |
US7674774B2 (en) | 2002-02-22 | 2010-03-09 | Shire Llc | Abuse-resistant amphetamine prodrugs |
US7678771B2 (en) | 2002-02-22 | 2010-03-16 | Shire Llc | Abuse-resistant amphetamine prodrugs |
US7678770B2 (en) | 2002-02-22 | 2010-03-16 | Shire Llc | Abuse-resistant amphetamine prodrugs |
US7659254B2 (en) | 2002-02-22 | 2010-02-09 | Shire Llc | Abuse-resistant amphetamine prodrugs |
US7687467B2 (en) | 2002-02-22 | 2010-03-30 | Shire Llc | Abuse-resistant amphetamine prodrugs |
US7700561B2 (en) | 2002-02-22 | 2010-04-20 | Shire Llc | Abuse-resistant amphetamine prodrugs |
US7713936B2 (en) | 2002-02-22 | 2010-05-11 | Shire Llc | Abuse-resistant amphetamine prodrugs |
US7718619B2 (en) | 2002-02-22 | 2010-05-18 | Shire Llc | Abuse-resistant amphetamine prodrugs |
US7723305B2 (en) | 2002-02-22 | 2010-05-25 | Shire Llc | Abuse-resistant amphetamine prodrugs |
US7662787B2 (en) | 2003-05-29 | 2010-02-16 | Shire Llc | Abuse resistant lysine amphetamine compounds |
US8106016B2 (en) | 2003-09-30 | 2012-01-31 | Shire Llc | Compounds and compositions for prevention of overdose of oxycodone |
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