GB1087585A - Improvements in or relating to tetrahydropyranylethers of steroids - Google Patents
Improvements in or relating to tetrahydropyranylethers of steroidsInfo
- Publication number
- GB1087585A GB1087585A GB1417065A GB1417065A GB1087585A GB 1087585 A GB1087585 A GB 1087585A GB 1417065 A GB1417065 A GB 1417065A GB 1417065 A GB1417065 A GB 1417065A GB 1087585 A GB1087585 A GB 1087585A
- Authority
- GB
- United Kingdom
- Prior art keywords
- steroids
- ols
- oacyl
- tetrahydropyranyloxy
- keto
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003431 steroids Chemical class 0.000 title abstract 2
- HUHXLHLWASNVDB-UHFFFAOYSA-N 2-(oxan-2-yloxy)oxane Chemical class O1CCCCC1OC1OCCCC1 HUHXLHLWASNVDB-UHFFFAOYSA-N 0.000 title 1
- -1 tetrahydropyranyloxy Chemical group 0.000 abstract 4
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 101100241859 Mus musculus Oacyl gene Proteins 0.000 abstract 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- QZLYKIGBANMMBK-UGCZWRCOSA-N 5α-Androstane Chemical compound C([C@@H]1CC2)CCC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CCC[C@@]2(C)CC1 QZLYKIGBANMMBK-UGCZWRCOSA-N 0.000 abstract 1
- BUDQDWGNQVEFAC-UHFFFAOYSA-N Dihydropyran Chemical compound C1COC=CC1 BUDQDWGNQVEFAC-UHFFFAOYSA-N 0.000 abstract 1
- 229930194542 Keto Natural products 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 230000001833 anti-estrogenic effect Effects 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- GRXPVLPQNMUNNX-MHJRRCNVSA-N estrane Chemical compound C1CC2CCCC[C@@H]2[C@@H]2[C@@H]1[C@@H]1CCC[C@@]1(C)CC2 GRXPVLPQNMUNNX-MHJRRCNVSA-N 0.000 abstract 1
- 239000000328 estrogen antagonist Substances 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 230000035558 fertility Effects 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000000468 ketone group Chemical group 0.000 abstract 1
- 230000014759 maintenance of location Effects 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003128 pregnanes Chemical class 0.000 abstract 1
- 230000001072 progestational effect Effects 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36217864A | 1964-04-23 | 1964-04-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1087585A true GB1087585A (en) | 1967-10-18 |
Family
ID=23424995
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1417065A Expired GB1087585A (en) | 1964-04-23 | 1965-04-02 | Improvements in or relating to tetrahydropyranylethers of steroids |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE662951A (enrdf_load_stackoverflow) |
| BR (1) | BR6569151D0 (enrdf_load_stackoverflow) |
| CH (1) | CH470377A (enrdf_load_stackoverflow) |
| GB (1) | GB1087585A (enrdf_load_stackoverflow) |
| NL (1) | NL6504857A (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1272102A (en) * | 1968-05-22 | 1972-04-26 | Syntex Corp | Steroid ethers |
-
1965
- 1965-04-02 GB GB1417065A patent/GB1087585A/en not_active Expired
- 1965-04-15 NL NL6504857A patent/NL6504857A/xx unknown
- 1965-04-22 CH CH558465A patent/CH470377A/de not_active IP Right Cessation
- 1965-04-23 BR BR16915165A patent/BR6569151D0/pt unknown
- 1965-04-23 BE BE662951D patent/BE662951A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL6504857A (enrdf_load_stackoverflow) | 1965-10-25 |
| BE662951A (enrdf_load_stackoverflow) | 1965-08-17 |
| BR6569151D0 (pt) | 1973-09-18 |
| CH470377A (de) | 1969-03-31 |
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