GB1085429A - Novel 1-[4-oxo-4-(4-fluorophenyl)-butyl]-piperidine derivatives and the production thereof - Google Patents
Novel 1-[4-oxo-4-(4-fluorophenyl)-butyl]-piperidine derivatives and the production thereofInfo
- Publication number
- GB1085429A GB1085429A GB39852/66A GB3985266A GB1085429A GB 1085429 A GB1085429 A GB 1085429A GB 39852/66 A GB39852/66 A GB 39852/66A GB 3985266 A GB3985266 A GB 3985266A GB 1085429 A GB1085429 A GB 1085429A
- Authority
- GB
- United Kingdom
- Prior art keywords
- fluorophenyl
- group
- acid addition
- oxo
- butyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- LUKOGYUKYPZBFP-UHFFFAOYSA-N 1-(4-fluorophenyl)-4-piperidin-1-ylbutan-1-one Chemical class C1=CC(F)=CC=C1C(=O)CCCN1CCCCC1 LUKOGYUKYPZBFP-UHFFFAOYSA-N 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 125000003386 piperidinyl group Chemical group 0.000 abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical group ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000000460 chlorine Chemical group 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Chemical group 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000000701 neuroleptic effect Effects 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEB0083682 | 1965-09-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1085429A true GB1085429A (en) | 1967-10-04 |
Family
ID=6982085
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB39852/66A Expired GB1085429A (en) | 1965-09-10 | 1966-09-06 | Novel 1-[4-oxo-4-(4-fluorophenyl)-butyl]-piperidine derivatives and the production thereof |
Country Status (8)
-
0
- NL NL128588D patent/NL128588C/xx active
-
1966
- 1966-09-02 CH CH1273466A patent/CH467780A/de unknown
- 1966-09-06 GB GB39852/66A patent/GB1085429A/en not_active Expired
- 1966-09-07 ES ES0330970A patent/ES330970A1/es not_active Expired
- 1966-09-09 NL NL6612730A patent/NL6612730A/xx unknown
- 1966-09-09 BE BE686678D patent/BE686678A/xx unknown
- 1966-09-09 SE SE12181/66A patent/SE326958B/xx unknown
- 1966-09-09 DK DK466666AA patent/DK115843B/da unknown
- 1966-12-06 FR FR86289A patent/FR6047M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL128588C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | |
| CH467780A (de) | 1969-01-31 |
| ES330970A1 (es) | 1967-10-01 |
| BE686678A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1967-03-09 |
| DK115843B (da) | 1969-11-17 |
| NL6612730A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1967-03-13 |
| SE326958B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1970-08-10 |
| FR6047M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1968-05-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES476786A1 (es) | Procedimiento para preparar nuevos derivados de tetrahidro- piridinilindol. | |
| GB1167563A (en) | Novel 3-(2-Substituted Ethyl) Indoles and Processes for Their Manufacture | |
| PH12022550436A1 (en) | Alpha-d-galactopyranoside derivatives | |
| ES340221A1 (es) | Procedimiento para la obtencion de nuevas hidroxi-ciclohe- xil-aminas. | |
| GB1062714A (en) | -ß-(4'-acyloxy-4'-piperidyl)-ketones | |
| GB1069797A (en) | ª-aminoketone derivatives | |
| GB1061306A (en) | 4-substituted-2-benzhydryl-2-butanol derivatives | |
| GB1085429A (en) | Novel 1-[4-oxo-4-(4-fluorophenyl)-butyl]-piperidine derivatives and the production thereof | |
| GB1174349A (en) | Novel 2-Anilinomethylimidazoline Derivatives and process for the preparation thereof | |
| KR840005140A (ko) | 인돌리진 유도체의 제조방법 | |
| GB1120186A (en) | Cyclohexene amino acid derivatives and process for their preparation | |
| NO173276C (no) | Analogifremgangsm}te for fremstilling av terapeutisk aktive 1,4-disubstituerte-piperidinylderivater | |
| GB1060498A (en) | Improvements in or relating to novel thiaxanthene oxide derivatives | |
| ES481855A1 (es) | Procedimiento para la preparacion de nuevos revidados de 6- metoxi-2-acetilnaftaleno oxima con actividad analgesica. | |
| GB1102357A (en) | Piperidine derivatives and process for their production | |
| GB1245155A (en) | NOVEL 5-SUBSTITUTED-gamma-CARBOLINE DERIVATIVES AND THE SALTS THEREOF | |
| ES336531A1 (es) | Procedimiento para preparar derivados del acido d-lisergi- co. | |
| GB1085066A (en) | Substituted alkylpiperidines and methods of preparation thereof | |
| GB1068985A (en) | Phenazine derivatives | |
| ES306443A1 (es) | Procedimiento de preparaciën de derivados de quinoleina | |
| GB1031082A (en) | Benzene derivatives | |
| GB1011039A (en) | Improvements in or relating to propynylamides | |
| GB1095912A (en) | Trans indolomorphinans and preparation thereof | |
| ES375495A1 (es) | Procedimiento para la preparacion de vetonas derivadas de la 1-(2-hidroxi-etil) piperazina. | |
| ES363527A1 (es) | Procedimiento para la obtencion de derivados de las benza- zocinas. |