GB1084164A - - Google Patents

Info

Publication number
GB1084164A
GB1084164A GB1084164DA GB1084164A GB 1084164 A GB1084164 A GB 1084164A GB 1084164D A GB1084164D A GB 1084164DA GB 1084164 A GB1084164 A GB 1084164A
Authority
GB
United Kingdom
Prior art keywords
march
alkyl
bisnor
uclaf
pyrollidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication of GB1084164A publication Critical patent/GB1084164A/en
Active legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1,084,164. Steroids. ROUSSEL-UCLAF. March 24, 1965 [March 25, 1964], No. 12483/65. Heading C2U. Novel 13#-alkyl (having 2-18 carbon atoms) 18,19 - bis - nor - pregn - 4 - ene - 3,20 - diones are obtained by reacting a 13#-alkyl-18,19-bisnor - 4,5 - seco - pregnane - 3,5,20 - trione with a cyclizing agent, e.g. hydrochloric acid or pyrrolidine. When pyrollidine is used the corresponding 3-enamine is formed and may be hydrolysed to obtain the desired 3-one. Pharmaceutical compositions having antiandrogenic activity and containing the above compounds are employed orally, parenterally, or as a suppository.
GB1084164D 1964-03-25 Active GB1084164A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR968659A FR1492767A (en) 1964-03-25 1964-03-25 Bis nor-18, 19 13-alkylated progesterone and method of preparation

Publications (1)

Publication Number Publication Date
GB1084164A true GB1084164A (en)

Family

ID=8826345

Family Applications (4)

Application Number Title Priority Date Filing Date
GB1084166D Active GB1084166A (en) 1964-03-25
GB1084167D Active GB1084167A (en) 1964-03-25
GB1084164D Active GB1084164A (en) 1964-03-25
GB1084165D Active GB1084165A (en) 1964-03-25

Family Applications Before (2)

Application Number Title Priority Date Filing Date
GB1084166D Active GB1084166A (en) 1964-03-25
GB1084167D Active GB1084167A (en) 1964-03-25

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB1084165D Active GB1084165A (en) 1964-03-25

Country Status (12)

Country Link
AT (1) AT267080B (en)
BE (1) BE660827A (en)
BR (1) BR6568071D0 (en)
CH (1) CH435265A (en)
DE (1) DE1468903A1 (en)
DK (1) DK112871B (en)
ES (1) ES310879A1 (en)
FR (1) FR1492767A (en)
GB (4) GB1084165A (en)
IL (3) IL30956A (en)
NL (1) NL6503835A (en)
SE (1) SE314067B (en)

Also Published As

Publication number Publication date
IL23183A (en) 1969-01-29
NL6503835A (en) 1965-09-27
FR1492767A (en) 1967-08-25
ES310879A1 (en) 1965-06-01
GB1084167A (en)
DE1468903A1 (en) 1969-01-16
GB1084166A (en)
IL30956A (en) 1969-02-27
DK112871B (en) 1969-01-27
BE660827A (en) 1965-09-09
AT267080B (en) 1968-12-10
GB1084165A (en)
SE314067B (en) 1969-09-01
CH435265A (en) 1967-05-15
BR6568071D0 (en) 1973-08-07
IL30955A (en) 1969-02-27

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