GB1065153A - Polymorph of lincomycin hydrochloride - Google Patents

Polymorph of lincomycin hydrochloride

Info

Publication number
GB1065153A
GB1065153A GB30932/64A GB3093264A GB1065153A GB 1065153 A GB1065153 A GB 1065153A GB 30932/64 A GB30932/64 A GB 30932/64A GB 3093264 A GB3093264 A GB 3093264A GB 1065153 A GB1065153 A GB 1065153A
Authority
GB
United Kingdom
Prior art keywords
polymorph
lincomycin hydrochloride
lincomycin
hydrochloride
encapsulating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB30932/64A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of GB1065153A publication Critical patent/GB1065153A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • C07H15/16—Lincomycin; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • C12R2001/565—Streptomyces lincolnensis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Polymorph II of lincomycin hydrochloride has a higher density than the normal polymorph I, is more suitable for encapsulating and has a characteristic X-ray diffraction pattern. It is obtained by adding acetone slowly with stirring to an aqueous solution of lincomycin hydrochloride at a temperature above 25 DEG C. Lincomycin hydrochloride polymorph I is prepared in Specification 976,765. A therapeutic composition in the form of a capsule contains lincomycin hydrochloride polymorph II.
GB30932/64A 1963-08-30 1964-08-04 Polymorph of lincomycin hydrochloride Expired GB1065153A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US305816A US3313695A (en) 1963-08-30 1963-08-30 Lincomycin hydrochloride crystals

Publications (1)

Publication Number Publication Date
GB1065153A true GB1065153A (en) 1967-04-12

Family

ID=23182472

Family Applications (1)

Application Number Title Priority Date Filing Date
GB30932/64A Expired GB1065153A (en) 1963-08-30 1964-08-04 Polymorph of lincomycin hydrochloride

Country Status (10)

Country Link
US (1) US3313695A (en)
BE (1) BE652505A (en)
BR (1) BR6462250D0 (en)
DE (1) DE1207551B (en)
DK (1) DK108966C (en)
ES (1) ES302960A2 (en)
FI (1) FI42817B (en)
GB (1) GB1065153A (en)
NL (1) NL6409689A (en)
SE (1) SE304081B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020022058A1 (en) * 2000-07-08 2002-02-21 Lovercheck Dale R. Unit dose of material in system and method

Also Published As

Publication number Publication date
SE304081B (en) 1968-09-16
NL6409689A (en) 1965-03-01
BE652505A (en)
DK108966C (en) 1968-03-04
DE1207551B (en) 1965-12-23
ES302960A2 (en) 1964-12-01
BR6462250D0 (en) 1973-08-07
FI42817B (en) 1970-08-03
US3313695A (en) 1967-04-11

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