GB1057473A - Novel benzdiaz[1,4]epine derivatives and a process for the manufacture thereof - Google Patents
Novel benzdiaz[1,4]epine derivatives and a process for the manufacture thereofInfo
- Publication number
- GB1057473A GB1057473A GB42651/65A GB4265165A GB1057473A GB 1057473 A GB1057473 A GB 1057473A GB 42651/65 A GB42651/65 A GB 42651/65A GB 4265165 A GB4265165 A GB 4265165A GB 1057473 A GB1057473 A GB 1057473A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- formula
- oxazirino
- hydrolysis
- benzdiaz
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
Compounds of the general Formula (I) <FORM:1057473/C2/1> (wherein the lower alkanoyl and lower alkyl groups each contain 1-7 carbon atoms and the broken lines denote optional substituents) and their acid addition salts are prepared by heating an oxazirino compound of the Formula (II) <FORM:1057473/C2/2> optionally followed by hydrolysis or hydrolysis and lower alkylation, and/or salt formation. The 1-(lower alkanoyl) compounds of Formula (I) are reconverted to the oxazirino compounds on exposure to light. The compounds of the invention are anti-convulsants, and some are tranquilizers and muscle relaxants. They may be administered enterally or parenterally in the form of pharmaceutical preparations (e.g. tablets, drag<\>aees, suppositories, capsules, solutions, emulsions and suspensions) containing them, with or without other (unspecified) active ingredients, together with a carrier.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26790863A | 1963-03-26 | 1963-03-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1057473A true GB1057473A (en) | 1967-02-01 |
Family
ID=23020651
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB12628/64A Expired GB1057471A (en) | 1963-03-26 | 1964-03-25 | Novel benzdiaz[1,4]epine derivatives and a process for the manufacture thereof |
| GB42650/65A Expired GB1057472A (en) | 1963-03-26 | 1964-03-25 | Novel benzdiaz[1,4]epine derivatives and a process for the preparation thereof |
| GB42651/65A Expired GB1057473A (en) | 1963-03-26 | 1964-03-25 | Novel benzdiaz[1,4]epine derivatives and a process for the manufacture thereof |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB12628/64A Expired GB1057471A (en) | 1963-03-26 | 1964-03-25 | Novel benzdiaz[1,4]epine derivatives and a process for the manufacture thereof |
| GB42650/65A Expired GB1057472A (en) | 1963-03-26 | 1964-03-25 | Novel benzdiaz[1,4]epine derivatives and a process for the preparation thereof |
Country Status (11)
| Country | Link |
|---|---|
| BE (1) | BE645624A (en) |
| BR (1) | BR6457465D0 (en) |
| CH (1) | CH461514A (en) |
| DE (3) | DE1695155A1 (en) |
| DK (1) | DK106911C (en) |
| ES (1) | ES298037A1 (en) |
| FR (1) | FR3276M (en) |
| GB (3) | GB1057471A (en) |
| IL (2) | IL20920A (en) |
| NL (1) | NL6403187A (en) |
| SE (3) | SE312340B (en) |
-
1964
- 1964-03-04 IL IL20920A patent/IL20920A/en unknown
- 1964-03-04 IL IL27973A patent/IL27973A/en unknown
- 1964-03-04 CH CH277064A patent/CH461514A/en not_active IP Right Cessation
- 1964-03-07 DE DE19641695155 patent/DE1695155A1/en active Pending
- 1964-03-07 DE DE19641445890 patent/DE1445890A1/en active Pending
- 1964-03-07 DE DE19641695154 patent/DE1695154A1/en active Pending
- 1964-03-11 BR BR157465/64A patent/BR6457465D0/en unknown
- 1964-03-20 SE SE3478/64A patent/SE312340B/xx unknown
- 1964-03-23 FR FR968263A patent/FR3276M/en not_active Expired
- 1964-03-24 BE BE645624D patent/BE645624A/xx unknown
- 1964-03-25 GB GB12628/64A patent/GB1057471A/en not_active Expired
- 1964-03-25 GB GB42650/65A patent/GB1057472A/en not_active Expired
- 1964-03-25 NL NL6403187A patent/NL6403187A/xx unknown
- 1964-03-25 GB GB42651/65A patent/GB1057473A/en not_active Expired
- 1964-03-25 ES ES298037A patent/ES298037A1/en not_active Expired
- 1964-03-31 DK DK159164AA patent/DK106911C/en active
-
1968
- 1968-06-13 SE SE07973/68A patent/SE329628B/xx unknown
- 1968-06-13 SE SE07974/68A patent/SE329171B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR3276M (en) | 1965-04-26 |
| SE329171B (en) | 1970-10-05 |
| DK106911C (en) | 1967-04-03 |
| GB1057471A (en) | 1967-02-01 |
| IL27973A (en) | 1968-07-25 |
| DE1695155A1 (en) | 1970-07-16 |
| GB1057472A (en) | 1967-02-01 |
| DE1695154A1 (en) | 1970-07-16 |
| IL20920A (en) | 1968-07-25 |
| DE1445890A1 (en) | 1969-02-06 |
| ES298037A1 (en) | 1964-09-01 |
| BR6457465D0 (en) | 1973-07-17 |
| BE645624A (en) | 1964-09-24 |
| NL6403187A (en) | 1964-09-28 |
| SE312340B (en) | 1969-07-14 |
| CH461514A (en) | 1968-08-31 |
| SE329628B (en) | 1970-10-19 |
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