GB1051286A - - Google Patents

Info

Publication number
GB1051286A
GB1051286A GB1051286DA GB1051286A GB 1051286 A GB1051286 A GB 1051286A GB 1051286D A GB1051286D A GB 1051286DA GB 1051286 A GB1051286 A GB 1051286A
Authority
GB
United Kingdom
Prior art keywords
oil
fatty acid
haloaryl
alkyl
natural fatty
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication of GB1051286A publication Critical patent/GB1051286A/en
Priority claimed from JP39032324A external-priority patent/JPS4832081B1/ja
Active legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09F—NATURAL RESINS; FRENCH POLISH; DRYING-OILS; DRIERS (SICCATIVES); TURPENTINE
    • C09F5/00—Obtaining drying-oils

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1,051,286. Fatty acid amides. SUMITOMO CHEMICAL CO. Ltd. April 28, 1965 [April 28, 1964; May 20, 1964; June 8, 1964; Aug. 28, 1964; Sept. 1, 1964; Sept. 5, 1964], No. 17959/65. Heading C2C. Novel N-substituted natural fatty acid amides having the general formula wherein R<SP>1</SP> is the residue of a natural fatty acid of hempseed oil, linseed oil, perilla oil, oiticica oil, kaya oil, water melon oil, soyabean oil, sunflower oil, rice bran oil, pumpkin oil, kaolliang oil, sesame oil, corn oil, cottonseed oil, cashew oil, tsubaki oil, ergot oil, peanut oil, lard, bone oil, horse fat, locust oil, crysalis oil, shark oil, cuttlefish oil, sardine oil, flatfish oil, horse mackerel oil, mackerel oil, saury pike oil, herring oil, cod oil, trout oil, grey mullet oil, tunney oil, menuke oil, menhaden oil, eel oil, or whale oils and R<SP>2</SP> is a substituted amino group of the formula wherein R<SP>3</SP> is an alkyl, alkenyl, cycloalkyl, alkylcycloalkyl, hydroxycycloalkyl, alkoxycycloalkyl, aryl, alkylaryl, hydroxyaryl, alkoxyaryl, haloaryl, haloalkylaryl, alkoxy-haloaryl, haloalkyl-haloaryl, aralkyl, alkylaralkyl, hydroxyalkyl or alkoxyaralkyl having a total of not more than 36 carbon atoms, R<SP>4</SP> is a hydrogen atom or an R<SP>3</SP> group, and R<SP>5</SP> is an alkylene group or an oxygen-containing alkylene or alkenylene group having a total of not more than 7 carbon atoms excepting those compounds wherein R<SP>3</SP> and R<SP>4</SP> are alkyl, or R<SP>3</SP> is alkyl and R<SP>4</SP> is hydrogen and R<SP>1</SP> is the residue of a fatty acid of linseed oil, poppyseed oil or soyabean oil, are obtained by reacting the said natural oil, natural fatty acid, or an ester of the natural fatty acid with an amine of the formula R<SP>2</SP>-H. Pharmaceutical compositions having cholesterol-lowering activity and containing the above compounds are administered orally.
GB1051286D 1964-04-28 Active GB1051286A (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP2406164 1964-04-28
JP2828464 1964-05-20
JP39032324A JPS4832081B1 (en) 1964-06-08 1964-06-08
JP4907364 1964-08-28
JP4981264 1964-09-01
JP5094764 1964-09-05

Publications (1)

Publication Number Publication Date
GB1051286A true GB1051286A (en)

Family

ID=27549142

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1051286D Active GB1051286A (en) 1964-04-28

Country Status (8)

Country Link
US (2) US3551462A (en)
BE (1) BE663071A (en)
CH (1) CH474478A (en)
DE (1) DE1493049B1 (en)
FR (2) FR4939M (en)
GB (1) GB1051286A (en)
NL (2) NL6505431A (en)
SE (1) SE334602B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751026A (en) * 1986-03-24 1988-06-14 Warner-Lambert Company Substituted anilides of oleic, linoleic, or linolenic acid as inhibitors of acyl-coa:cholesterol acyltransferase

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3995059A (en) * 1966-10-04 1976-11-30 Sumitomo Chemical Company, Limited Pharmaceutical compositions containing fatty acid amide derivatives
US4115587A (en) * 1976-02-04 1978-09-19 A. H. Robins Company, Inc. Fatty acid amides of norfenfluramine and compositions and methods thereof
US4229463A (en) * 1978-02-27 1980-10-21 Sandoz, Inc. Unsaturated fatty acid hydrazides
US4194002A (en) * 1978-03-29 1980-03-18 Sandoz, Inc. Cholesterol ester-reducing amides of hexahydroindolinols
US4201785A (en) * 1978-02-27 1980-05-06 Sandoz Inc. Cyclopropanyl-bearing hydrazides
US4248893A (en) * 1978-12-30 1981-02-03 Sandoz, Inc. Arterial wall cholesterol ester reducing cyclopropanyl-bearing amides
US4663353A (en) * 1979-03-06 1987-05-05 The United States Of America As Represented By The Secretary Of Agriculture Antibacterial fatty anilides
EP0091519B1 (en) * 1982-04-08 1987-06-24 Johnson &amp; Johnson Products Inc. Topical acylaminophenols
US4544668A (en) * 1983-07-14 1985-10-01 The Procter & Gamble Company Compounds and compositions useful for producing analgesia
US4544669A (en) * 1983-07-14 1985-10-01 The Procter & Gamble Company Compounds and compositions useful for producing analgesia
US4980366A (en) * 1986-08-19 1990-12-25 Warner-Lambert Co. Amide, sulfonamide, urea, carbamate, thiocarbamate, and thiourea derivatives of 4'hydroxybenzylamine having anti-inflammatory and analgesic activity
FR2673625B1 (en) * 1991-03-08 1993-05-07 Adir NOVEL ACYLAMINOPHENOL DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2978381A (en) * 1958-06-20 1961-04-04 Freedman Louis Process and composition for lowering blood serum cholesterol and chylomicron levels
US3193458A (en) * 1961-07-12 1965-07-06 Us Vitamin Pharm Corp Method of lowering blood cholesterol level
US3250794A (en) * 1962-05-24 1966-05-10 Robert R Mod Fatty acid amides and esters thereof
US3219612A (en) * 1963-02-25 1965-11-23 Evald L Skau Vinyl chloride resins and butadiene rubbers with n-acyl derivatives of cyclic imines

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751026A (en) * 1986-03-24 1988-06-14 Warner-Lambert Company Substituted anilides of oleic, linoleic, or linolenic acid as inhibitors of acyl-coa:cholesterol acyltransferase

Also Published As

Publication number Publication date
DE1493049B1 (en) 1971-09-30
NL130295C (en)
US3551462A (en) 1970-12-29
CH474478A (en) 1969-06-30
BE663071A (en) 1965-10-27
FR1602617A (en) 1971-01-04
US3741999A (en) 1973-06-26
SE334602B (en) 1971-05-03
NL6505431A (en) 1965-10-29
FR4939M (en) 1967-03-28

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