GB1048798A - Process for the production of thiazolidinones - Google Patents

Process for the production of thiazolidinones

Info

Publication number
GB1048798A
GB1048798A GB4591765A GB4591765A GB1048798A GB 1048798 A GB1048798 A GB 1048798A GB 4591765 A GB4591765 A GB 4591765A GB 4591765 A GB4591765 A GB 4591765A GB 1048798 A GB1048798 A GB 1048798A
Authority
GB
United Kingdom
Prior art keywords
alkyl
isobutenyl
substituted
isocyanates
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4591765A
Inventor
Kurt Ley
Roland Nast
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of GB1048798A publication Critical patent/GB1048798A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/18—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

The invention comprises thiazolidinones of formula <FORM:1048798/C2/1> wherein R1 is an alkyl, aryl (which may be substituted by halogen atoms or nitro groups), aroyl, cycloalkyl, alkoxyaryl or aryl sulphonyl group or an alkyl or aryl group substituted by a radical of the formula <FORM:1048798/C2/2> R2 and R3 each represent an alkyl group or together form a hydrocarbon ring, and R4 and R3 each represent an alkyl group or together with the nitrogen atom, form a heterocyclic ring, optionally with further hetero atoms which may be substituted by a radical of the formula <FORM:1048798/C2/3> They are prepared by reacting an enamine whose b -carbon atom is substituted by alkyl radicals with sulphur or a sulphur producing compound such as trimethylamine polysulphides or xanthogenate polysulphides, and an isocyanate. The reaction is suitably carried out in an inert solvent at temperatures in the range of 10 DEG to 150 DEG C. Preferred enamines for the process are isobutenyl morpholine, isobutenyl piperidine, isobutenyl-N-methyl piperazine, isobutenyl-di-n-butyl amine and isobutenyl - di - n - isopropylamine, but others are listed. Suitable isocyanates include aryl isocyanates or arylene diisocyanates which may be substituted by alkyl, alkoxy, carboxyalkyl, halogen or nitro groups, alkyl isocyanates, alkylene diisocyanates, cycloalkyl isocyanates, aryl sulphonyl and benzoyl isocyanates. A large number of compounds of the invention are specified.
GB4591765A 1964-10-30 1965-10-29 Process for the production of thiazolidinones Expired GB1048798A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEF0044346 1964-10-30

Publications (1)

Publication Number Publication Date
GB1048798A true GB1048798A (en) 1966-11-23

Family

ID=7099992

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4591765A Expired GB1048798A (en) 1964-10-30 1965-10-29 Process for the production of thiazolidinones

Country Status (4)

Country Link
BE (1) BE671637A (en)
DE (1) DE1445784A1 (en)
GB (1) GB1048798A (en)
NL (1) NL6513032A (en)

Also Published As

Publication number Publication date
DE1445784A1 (en) 1968-11-21
BE671637A (en) 1966-04-29
NL6513032A (en) 1966-05-02

Similar Documents

Publication Publication Date Title
US2837519A (en) Accelerator of vulcanization of rubber
GB1499485A (en) Thiocarbamide derivatives and process for their preparation
US3086018A (en) Manufacture of amino thiazole disulfides
US2850496A (en) Preparation of amino azole disulfides
KR840008157A (en) Process for preparing carbapenem derivatives
FI800224A (en) 2-HYDROXY-PETROLEUM DERIVATIVES AND CONDITIONS FOR THE CONDITION OF COMPOUNDS AND DIAZOTYPES
GB1048798A (en) Process for the production of thiazolidinones
GB944529A (en) Improvements relating to the production of organic isothiocyanates
GB1420409A (en) Thiocarbamyl sulphenamides
GB1087174A (en) Piperidine derivatives
ES333485A1 (en) Procedure for the preparation of new substituteed urea derivatives. (Machine-translation by Google Translate, not legally binding)
GB1080680A (en) Process for the preparation of iminopyrrolidine derivatives
GB1043672A (en) Biuret polyisocyanates and production thereof
GB1047061A (en) Polymers and a process for the preparation thereof
ATE19509T1 (en) SUBSTITUTED BENZYLCYCLOALKENYLUREA DERIVATIVES.
US2602796A (en) 1-carbamyl-4-thiazolyl piperazines
GB901455A (en) C-substituted piperazinones and the manufacture thereof
GB950715A (en) New tetrahydro-quinolines and tetrahydro-isoquinolines
GB738013A (en) New nitrogen containing heterocyclic compounds
US3225041A (en) Process for producing 2,6-diamino pyridines
US3317575A (en) Heterocycles having in the ring thereof an element from group v-a
GB845447A (en) Thiophosphoric acid esters
GB980277A (en) Improvements in or relating to preparation of cyclic amines
US3681379A (en) 2-carbamyl-2-imidazolines and method for their production
ES331789A1 (en) Procedure for the preparation of derivatives of 2-anilino-1,3-diazaciclopenteno- (2) with sedative action and depression of the blood pressure. (Machine-translation by Google Translate, not legally binding)