GB1036621A - Improvements in or relating to bacterial vaccines - Google Patents

Improvements in or relating to bacterial vaccines

Info

Publication number
GB1036621A
GB1036621A GB6820/63A GB682063A GB1036621A GB 1036621 A GB1036621 A GB 1036621A GB 6820/63 A GB6820/63 A GB 6820/63A GB 682063 A GB682063 A GB 682063A GB 1036621 A GB1036621 A GB 1036621A
Authority
GB
United Kingdom
Prior art keywords
vaccines
dornase
staphylococci
infections
derived
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB6820/63A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Canadian Patents and Development Ltd
Original Assignee
Canadian Patents and Development Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Canadian Patents and Development Ltd filed Critical Canadian Patents and Development Ltd
Publication of GB1036621A publication Critical patent/GB1036621A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0275—Salmonella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/085—Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Somatic antigen vaccines are prepared by lysing the killed cells of at least one selected strain of pathogenic bacteria other than staphylococci by exposing them to the action of dornase. It is preferred to inactivate the dornase but this must be done without destroying the antigenic properties of the vaccine e.g. by heating at 56 DEG C for 1 hour. Vaccines derived from staphylococci may be obtained in this preferred way, especially vaccines for treating mastitis in cattle and derived from mixed strains of both staphylococci and streptococci. A proteolytic enzyme such as trypsin may be added to the dornase and lysis may be expedited by the further addition of a wetting agent. Examples relate to the preparation of vaccines effective against staphylococcal infections, typhoid, meningococcal infections, pertussis, streptococcal infections, BCG and mastitis.
GB6820/63A 1962-02-23 1963-02-20 Improvements in or relating to bacterial vaccines Expired GB1036621A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA843020 1962-02-23
CA851099 1962-06-08

Publications (1)

Publication Number Publication Date
GB1036621A true GB1036621A (en) 1966-07-20

Family

ID=25673389

Family Applications (1)

Application Number Title Priority Date Filing Date
GB6820/63A Expired GB1036621A (en) 1962-02-23 1963-02-20 Improvements in or relating to bacterial vaccines

Country Status (2)

Country Link
FR (1) FR2774M (en)
GB (1) GB1036621A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2510987A1 (en) * 1974-10-29 1976-05-13 Behringwerke Ag Atoxic, immunogenic prod. from tetanus toxin - by treatment with proteinase, giving vaccines which cause fewer reactions on inoculation
EP0174106A2 (en) * 1984-08-23 1986-03-12 Becton Dickinson and Company Detection of cell membrane protein
US5576003A (en) * 1992-10-14 1996-11-19 Akzo Nobel N.V. Ornithobacterium rhinotracheale vaccine and method of immunization

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2510987A1 (en) * 1974-10-29 1976-05-13 Behringwerke Ag Atoxic, immunogenic prod. from tetanus toxin - by treatment with proteinase, giving vaccines which cause fewer reactions on inoculation
EP0174106A2 (en) * 1984-08-23 1986-03-12 Becton Dickinson and Company Detection of cell membrane protein
EP0174106A3 (en) * 1984-08-23 1986-03-26 Becton, Dickinson And Company Detection of cell membrane protein
AU582170B2 (en) * 1984-08-23 1989-03-16 Becton Dickinson & Company Detection of cell membrane protein
US5576003A (en) * 1992-10-14 1996-11-19 Akzo Nobel N.V. Ornithobacterium rhinotracheale vaccine and method of immunization
US5925361A (en) * 1992-10-14 1999-07-20 Akzo Nobel, N.V. Ornithobacterium rhinotracheale vaccines
US6114131A (en) * 1992-10-14 2000-09-05 Akzo Nobel N.V. Methods for the detection of antibodies to ornithobacterium rhinotracheale

Also Published As

Publication number Publication date
FR2774M (en) 1964-09-07

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