GB970365A - Preparations for the treatment of tumours - Google Patents

Preparations for the treatment of tumours

Info

Publication number
GB970365A
GB970365A GB426/61A GB42661A GB970365A GB 970365 A GB970365 A GB 970365A GB 426/61 A GB426/61 A GB 426/61A GB 42661 A GB42661 A GB 42661A GB 970365 A GB970365 A GB 970365A
Authority
GB
United Kingdom
Prior art keywords
spores
aqueous suspension
treatment
clostridium butyricum
tumours
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB426/61A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Farbwerke Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG, Farbwerke Hoechst AG filed Critical Hoechst AG
Publication of GB970365A publication Critical patent/GB970365A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A therapeutic preparation for the treatment of tumours comprises spores of Clostridium butyricum ATCC 13732 in admixture or conjunction with a physiologically tolerable carrier for parenteral administration. The preparation may be an aqueous suspension or lyophilized solid. A bacterial endotoxin, e.g. a lipopolysaccharide from gram-negative bacteria, may also be present. The spores of Clostridium butyricum ATCC 13732 may be produced by cultivating the microorganism according to known methods for the cultivation of this species until a substantial sporulation is achieved, washing the spores with physiological saline, bringing them into aqueous suspension, killing the bacteria present in the resulting aqueous suspension by heating to 73 DEG C. and adjusting the resultant dispersion of spores to the desired concentration.
GB426/61A 1960-01-27 1961-01-04 Preparations for the treatment of tumours Expired GB970365A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEF0003040 1960-01-27

Publications (1)

Publication Number Publication Date
GB970365A true GB970365A (en) 1964-09-23

Family

ID=7083647

Family Applications (1)

Application Number Title Priority Date Filing Date
GB426/61A Expired GB970365A (en) 1960-01-27 1961-01-04 Preparations for the treatment of tumours

Country Status (1)

Country Link
GB (1) GB970365A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017074257A1 (en) * 2015-10-26 2017-05-04 Nanyang Technological University Non-viable derivatives of clostridium sporogenes as anti-cancer therapeutic agents

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017074257A1 (en) * 2015-10-26 2017-05-04 Nanyang Technological University Non-viable derivatives of clostridium sporogenes as anti-cancer therapeutic agents

Similar Documents

Publication Publication Date Title
Dubos et al. Reversible changes in the susceptibility of mice to bacterial infections: I. Changes brought about by injection of pertussis vaccine or of bacterial endotoxins
Okamoto et al. Studies on the anticancer and streptolysin S-forming abilities of hemolytic streptococci
US3192116A (en) Anti-tumor clostridium composition
US3649454A (en) Bacteriolytic enzyme and process for the production thereof
Ginsburg et al. Effect of streptococcal haemolysins on Ehrlich ascites tumour cells
Taylor et al. The action of chloroform-killed suspensions of enteropathogenic Escherichia coli on ligated rabbit-gut segments
Smith The immunity to Salmonella gallinarum infection in chickens produced by live cultures of members of the Salmonella genus
GB970365A (en) Preparations for the treatment of tumours
US3987164A (en) Method for prevention of pseudomonas aeruginosa infections
Anigstein et al. Para-aminobenzoic acid—its effectiveness in spotted fever in guinea pigs
Hoffman et al. Effects of high incubation temperature upon the cell wall of Escherichia coli
ES2104817T3 (en) CULTURE LYOPHILIZATE CONTAINING MICROORGANISMS WITH PROLIFERATIVE STRAINS, PROCEDURE FOR THE PREPARATION AND USE.
Arndt et al. Synergism between staphylococci and proteus in mixed infection.
GB944173A (en) Improvements in or relating to harrows, cultivators and like agricultural implements
ES402137A1 (en) Antibiotic em{14 49
Schütze Studies in B. pestis antigens: Iii. The prophylactic value of the envelope and somatic antigens of B. pestis
Fisher Experimental Staphylococcal Infection of the Subcutaneous Tissue of the Mouse: II. Promotion of the Infection with Staphylococcal Cells and Products
ES476703A1 (en) Heterovaccine against the trichomonas syndrome, and process for its preparation
DE2921829C2 (en)
US1476233A (en) Biological product
Hassall Subtilin C: an antibiotic concentrate from Bacillus subtilis
Nakayama et al. Studies on ilamycin
Sato et al. Immunogenicity of highly purified α-toxoid of Clostridium perfringens
IL59724A0 (en) Pentadecapeptide and its salts,their preparation and pharmaceutical compositions containing them
Springer et al. Protection of mice against lethal Staphylococcus infection by Escherichia coli O86 fractions