GB970365A - Preparations for the treatment of tumours - Google Patents

Preparations for the treatment of tumours

Info

Publication number
GB970365A
GB970365A GB426/61A GB42661A GB970365A GB 970365 A GB970365 A GB 970365A GB 426/61 A GB426/61 A GB 426/61A GB 42661 A GB42661 A GB 42661A GB 970365 A GB970365 A GB 970365A
Authority
GB
United Kingdom
Prior art keywords
spores
aqueous suspension
treatment
clostridium butyricum
tumours
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB426/61A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Farbwerke Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG, Farbwerke Hoechst AG filed Critical Hoechst AG
Publication of GB970365A publication Critical patent/GB970365A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A therapeutic preparation for the treatment of tumours comprises spores of Clostridium butyricum ATCC 13732 in admixture or conjunction with a physiologically tolerable carrier for parenteral administration. The preparation may be an aqueous suspension or lyophilized solid. A bacterial endotoxin, e.g. a lipopolysaccharide from gram-negative bacteria, may also be present. The spores of Clostridium butyricum ATCC 13732 may be produced by cultivating the microorganism according to known methods for the cultivation of this species until a substantial sporulation is achieved, washing the spores with physiological saline, bringing them into aqueous suspension, killing the bacteria present in the resulting aqueous suspension by heating to 73 DEG C. and adjusting the resultant dispersion of spores to the desired concentration.
GB426/61A 1960-01-27 1961-01-04 Preparations for the treatment of tumours Expired GB970365A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEF0003040 1960-01-27

Publications (1)

Publication Number Publication Date
GB970365A true GB970365A (en) 1964-09-23

Family

ID=7083647

Family Applications (1)

Application Number Title Priority Date Filing Date
GB426/61A Expired GB970365A (en) 1960-01-27 1961-01-04 Preparations for the treatment of tumours

Country Status (1)

Country Link
GB (1) GB970365A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017074257A1 (en) * 2015-10-26 2017-05-04 Nanyang Technological University Non-viable derivatives of clostridium sporogenes as anti-cancer therapeutic agents

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017074257A1 (en) * 2015-10-26 2017-05-04 Nanyang Technological University Non-viable derivatives of clostridium sporogenes as anti-cancer therapeutic agents

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