GB1028205A - Improvements in or relating to medicinal compositions and method for relieving cough - Google Patents

Improvements in or relating to medicinal compositions and method for relieving cough

Info

Publication number
GB1028205A
GB1028205A GB31047/63A GB3104763A GB1028205A GB 1028205 A GB1028205 A GB 1028205A GB 31047/63 A GB31047/63 A GB 31047/63A GB 3104763 A GB3104763 A GB 3104763A GB 1028205 A GB1028205 A GB 1028205A
Authority
GB
United Kingdom
Prior art keywords
amino
methyl
amine
relating
heptane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB31047/63A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith Kline and French Laboratories Ltd
Original Assignee
Smith Kline and French Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline and French Laboratories Ltd filed Critical Smith Kline and French Laboratories Ltd
Publication of GB1028205A publication Critical patent/GB1028205A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

An inhalant composition comprises as the essential active ingredient 2-amino-6-methyl heptane. It may be used in admixture with a vaso-constrictor amine, e.g. 1-cyclohexyl-2 methylamino propane, 1-cyclopentyl-2-aminopropane, 2-amino-4-methyl hexane, N-methyl phenyl tertiary butylamine, 2-aminoheptane or 1-1-phenyl2-methylaminopropane. The ratio of 2-amino6-methyl heptane to vasoconstrictor amine may range from 1 : 1 to 9 : 1. An inert liquid vehicle, e.g. dibutyl phthalate or benzyl salicylate, may be used. Compounds which reduce the vapour pressures of the specified amenes, e.g. alcohols, glycols, and essential oils, may also be incorporated. Flavouring agents, e.g. menthol or oil of lavender, may also be added. The amines may be treated with carbon dioxide in the presence or absence of water to form carbamates or carbonates. A vapor dosage of 0.25 mg.-1.5 mg. of 2-amino-6-methylheptane may be administered intranasally from 1 to 8 times per day using conventional pocket inhalers.
GB31047/63A 1962-08-23 1963-08-06 Improvements in or relating to medicinal compositions and method for relieving cough Expired GB1028205A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US218867A US3156614A (en) 1962-08-23 1962-08-23 Medicinal compositions and method for relieving cough

Publications (1)

Publication Number Publication Date
GB1028205A true GB1028205A (en) 1966-05-04

Family

ID=22816805

Family Applications (1)

Application Number Title Priority Date Filing Date
GB31047/63A Expired GB1028205A (en) 1962-08-23 1963-08-06 Improvements in or relating to medicinal compositions and method for relieving cough

Country Status (3)

Country Link
US (1) US3156614A (en)
FR (1) FR2944M (en)
GB (1) GB1028205A (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL299042A (en) * 1962-10-10
WO2010019255A1 (en) * 2008-08-13 2010-02-18 Virun, Inc. Compositions containing aminoalkanes and aminoalkane derivatives
US9351517B2 (en) 2013-03-15 2016-05-31 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and compositions containing same
US10610512B2 (en) 2014-06-26 2020-04-07 Island Breeze Systems Ca, Llc MDI related products and methods of use
EP3297710A4 (en) * 2015-05-21 2019-05-01 Island Breeze Systems Ca, LLC Propellant based metered dose inhaler and food applicators and applicators
US11806645B1 (en) 2019-05-07 2023-11-07 Cannaceutical Extractions LLC Methods of producing CBD/THC oils

Also Published As

Publication number Publication date
US3156614A (en) 1964-11-10
FR2944M (en) 1964-11-23

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