GB1021525A - New isoquinolines and process for preparing them - Google Patents
New isoquinolines and process for preparing themInfo
- Publication number
- GB1021525A GB1021525A GB720464A GB720464A GB1021525A GB 1021525 A GB1021525 A GB 1021525A GB 720464 A GB720464 A GB 720464A GB 720464 A GB720464 A GB 720464A GB 1021525 A GB1021525 A GB 1021525A
- Authority
- GB
- United Kingdom
- Prior art keywords
- isoquinoline
- methyl
- isoquinolines
- preparing
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention comprises 1-morpholino-3-(morpholino - methyl) - 4 - methyl - isoquinoline, and salts thereof, and its preparation by reacting morpholine with a 4-methyl-3-morpholinomethyl - 1 - halo - isoquinoline (preferable in situ from a 4-methyl-3-halomethyl-1-halo-isoquinoline). Isoquinoline precursors also mentioned are 4-monomethyl-and 4,4-dimethyl-1,3-dioxo-1,2,3,4-tetrahydroisoquinoline. Pharmaceutical compositions incorporate compounds of the invention, forms for oral and parenteral administration as antitussives being described.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH220563A CH449013A (en) | 1963-02-21 | 1963-02-21 | Process for the preparation of new isoquinoline compounds |
CH67264 | 1964-01-21 | ||
CH67164 | 1964-01-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1021525A true GB1021525A (en) | 1966-03-02 |
Family
ID=27172297
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB720464A Expired GB1021525A (en) | 1963-02-21 | 1964-02-20 | New isoquinolines and process for preparing them |
GB720564A Expired GB1021526A (en) | 1963-02-21 | 1964-02-20 | New isquinolines and process for preparing them |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB720564A Expired GB1021526A (en) | 1963-02-21 | 1964-02-20 | New isquinolines and process for preparing them |
Country Status (4)
Country | Link |
---|---|
BE (2) | BE644126A (en) |
FR (2) | FR3534M (en) |
GB (2) | GB1021525A (en) |
NL (2) | NL6401593A (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7824661B2 (en) | 2002-03-11 | 2010-11-02 | Molecular Insight Pharmaceuticals, Inc. | Technetium- and rhenium-bis(heteroaryl) complexes, and methods of use thereof |
AU2003213819C1 (en) | 2002-03-11 | 2010-03-04 | Molecular Insight Pharmaceuticals, Inc. | Technetium-dipyridine complexes, and methods of use thereof |
EP1718342A4 (en) * | 2004-02-12 | 2009-07-22 | Molecular Insight Pharm Inc | Technetium-and rhenium-bis(heteroaryl) complexes, and methods of use thereof |
-
1964
- 1964-02-20 NL NL6401593A patent/NL6401593A/xx unknown
- 1964-02-20 BE BE644126A patent/BE644126A/xx unknown
- 1964-02-20 BE BE644127A patent/BE644127A/xx unknown
- 1964-02-20 NL NL6401592A patent/NL6401592A/xx unknown
- 1964-02-20 GB GB720464A patent/GB1021525A/en not_active Expired
- 1964-02-20 GB GB720564A patent/GB1021526A/en not_active Expired
- 1964-05-20 FR FR975038A patent/FR3534M/en active Active
- 1964-05-20 FR FR975039A patent/FR3782M/en active Active
Also Published As
Publication number | Publication date |
---|---|
GB1021526A (en) | 1966-03-02 |
FR3782M (en) | 1965-12-27 |
NL6401592A (en) | 1964-08-24 |
BE644126A (en) | 1964-08-20 |
FR3534M (en) | 1965-09-13 |
NL6401593A (en) | 1964-08-24 |
BE644127A (en) | 1964-08-20 |
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