GB1020804A - Novel cyclopropa-no-steroid compounds and means for producing the same - Google Patents
Novel cyclopropa-no-steroid compounds and means for producing the sameInfo
- Publication number
- GB1020804A GB1020804A GB4774/64A GB477464A GB1020804A GB 1020804 A GB1020804 A GB 1020804A GB 4774/64 A GB4774/64 A GB 4774/64A GB 477464 A GB477464 A GB 477464A GB 1020804 A GB1020804 A GB 1020804A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methyl
- compounds
- testosterone
- cyclopropa
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Abstract
The invention comprises compounds of formula <FORM:1020804/C2/1> wherein Z, R, R1 and R2 are hydrogen atoms or Z is a methyl group, R1 and R2 are hydrogen atoms or methyl groups and R2 is a hydrogen atom or an alkanoyl group of not more than 4 carbon atoms, and their preparation by (a) reaction of a compound of formula <FORM:1020804/C2/2> with hydrazine under basic conditions in a hydroxylic organic solvent; or (b) 17-acylation of compounds in which R2 = H to produce compounds in which R2 = alkanoyl. The compounds of the invention have analolin activity. 2 - Ethylidene - 17a - methyl - testosterone is prepared by reaction of 17a -methyl-testosterone with diethyl oxalate and sodium hydride to give 2 - ethyloxalyl - 17a - methyl - testosterone, and reacting this with acetaldehyde.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4774/64A GB1020804A (en) | 1964-02-04 | 1964-02-04 | Novel cyclopropa-no-steroid compounds and means for producing the same |
| US425928A US3308138A (en) | 1964-02-04 | 1965-01-15 | Cyclopropa-androstene compounds |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4774/64A GB1020804A (en) | 1964-02-04 | 1964-02-04 | Novel cyclopropa-no-steroid compounds and means for producing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1020804A true GB1020804A (en) | 1966-02-23 |
Family
ID=9783565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4774/64A Expired GB1020804A (en) | 1964-02-04 | 1964-02-04 | Novel cyclopropa-no-steroid compounds and means for producing the same |
Country Status (2)
| Country | Link |
|---|---|
| US (1) | US3308138A (en) |
| GB (1) | GB1020804A (en) |
-
1964
- 1964-02-04 GB GB4774/64A patent/GB1020804A/en not_active Expired
-
1965
- 1965-01-15 US US425928A patent/US3308138A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US3308138A (en) | 1967-03-07 |
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