GB1019781A - - Google Patents
Info
- Publication number
- GB1019781A GB1019781A GB1019781DA GB1019781A GB 1019781 A GB1019781 A GB 1019781A GB 1019781D A GB1019781D A GB 1019781DA GB 1019781 A GB1019781 A GB 1019781A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- acylamino
- alkyl
- unless
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Abstract
1,019,781. Derivatives of p-aminosalicyl- (aminoalkyl)amides. SOC. D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILEFRANCE. April 27, 1964, No. 17338/64. Heading C2C. Compounds of formula wherein A is H or alkyl, n is 2 or 3, X is amino, alkylamino, dialkylamino or acylamino, Y is halogen, nitro or any group listed for X, one of the CH 2 groups may be replaced by CHR 5 and R 1 , R 2 and R 5 are C 1-5 alkyl or -NR 1 R 2 may form a heterocyclic ring; are prepared by esterifying p-aminosalicylic acid, acylating the amino group, alkylating the OH group (unless A=H), introducing group Y, reacting the ester group with NH 2 (CH 2 ) n NR 1 R 2 and (unless X= acylamino) hydrolysing the acylamino group, with optional alkylation of the product.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR926941A FR1407055A (en) | 1963-03-05 | 1963-03-05 | New process for the preparation of substituted benzamides |
GB1733864 | 1964-04-27 | ||
DES0090796 | 1964-04-27 | ||
BE648164A BE648164A (en) | 1963-03-05 | 1964-05-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1019781A true GB1019781A (en) |
Family
ID=27424769
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1019781D Active GB1019781A (en) | 1963-03-05 |
Country Status (2)
Country | Link |
---|---|
DE (1) | DE1518271C3 (en) |
GB (1) | GB1019781A (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4885551A (en) * | 1972-02-17 | 1973-11-13 | ||
JPS49125333A (en) * | 1973-04-05 | 1974-11-30 | ||
EP0213775A1 (en) | 1985-08-06 | 1987-03-11 | Walton S.A. | New Benzamides |
US5026858A (en) * | 1976-11-16 | 1991-06-25 | Walton S.A. | Piperidine derivative |
CN107540568A (en) * | 2017-08-25 | 2018-01-05 | 许昌恒生制药有限公司 | A kind of preparation method of ethopabate |
CN113698321A (en) * | 2021-09-30 | 2021-11-26 | 内蒙古康普药业有限公司 | New metoclopramide diamine impurity and application |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4808624A (en) * | 1984-06-28 | 1989-02-28 | Bristol-Myers Company | Pharmacologically active substituted benzamides |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL281394A (en) * | 1961-07-25 |
-
0
- GB GB1019781D patent/GB1019781A/en active Active
-
1964
- 1964-04-27 DE DE1518271A patent/DE1518271C3/en not_active Expired
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4885551A (en) * | 1972-02-17 | 1973-11-13 | ||
JPS49125333A (en) * | 1973-04-05 | 1974-11-30 | ||
US5026858A (en) * | 1976-11-16 | 1991-06-25 | Walton S.A. | Piperidine derivative |
EP0213775A1 (en) | 1985-08-06 | 1987-03-11 | Walton S.A. | New Benzamides |
CN107540568A (en) * | 2017-08-25 | 2018-01-05 | 许昌恒生制药有限公司 | A kind of preparation method of ethopabate |
CN113698321A (en) * | 2021-09-30 | 2021-11-26 | 内蒙古康普药业有限公司 | New metoclopramide diamine impurity and application |
Also Published As
Publication number | Publication date |
---|---|
DE1518271C3 (en) | 1983-03-17 |
DE1518271B2 (en) | 1974-01-24 |
DE1518271A1 (en) | 1970-12-17 |
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