GB1019162A - Process for the preparation of phospholipid antithromboplastins - Google Patents
Process for the preparation of phospholipid antithromboplastinsInfo
- Publication number
- GB1019162A GB1019162A GB2373/63A GB237363A GB1019162A GB 1019162 A GB1019162 A GB 1019162A GB 2373/63 A GB2373/63 A GB 2373/63A GB 237363 A GB237363 A GB 237363A GB 1019162 A GB1019162 A GB 1019162A
- Authority
- GB
- United Kingdom
- Prior art keywords
- phospholipid
- antithromboplastins
- preparation
- temperature
- alcohol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003904 phospholipids Chemical class 0.000 title abstract 4
- 230000003186 anti-thromboplastin Effects 0.000 title abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 244000068988 Glycine max Species 0.000 abstract 1
- 235000010469 Glycine max Nutrition 0.000 abstract 1
- 240000008042 Zea mays Species 0.000 abstract 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 abstract 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 abstract 1
- 230000003445 anti-thromboplastic effect Effects 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 235000005822 corn Nutrition 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 210000003734 kidney Anatomy 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
- C07F9/103—Extraction or purification by physical or chemical treatment of natural phosphatides; Preparation of compositions containing phosphatides of unknown structure
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Phospholipid antithromboplastins are produced by heating the alcohol insoluble portion of a phospholipid which has previously been separated from the alcohol soluble portion at a temperature of 40 DEG to 90 DEG C. which is below the decomposition temperature of the material, for between 1 and 21 days until the material acquires antithromboplastic activity. The phospholipid may be obtained from liver, kidney, brain, soybean or corn.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16743762A | 1962-01-19 | 1962-01-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1019162A true GB1019162A (en) | 1966-02-02 |
Family
ID=22607377
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2373/63A Expired GB1019162A (en) | 1962-01-19 | 1963-01-18 | Process for the preparation of phospholipid antithromboplastins |
Country Status (4)
Country | Link |
---|---|
DE (1) | DE1174940B (en) |
ES (1) | ES283985A1 (en) |
FR (1) | FR1514910A (en) |
GB (1) | GB1019162A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20130012473A1 (en) * | 2010-03-17 | 2013-01-10 | Ktb Tumorforschungsgesellschaft Mbh | Combined use of phospholipid and sulfate groups-carrying polysaccharides for inhibiting metastatic spread |
-
1962
- 1962-01-07 ES ES283985A patent/ES283985A1/en not_active Expired
-
1963
- 1963-01-05 DE DEA42027A patent/DE1174940B/en active Pending
- 1963-01-17 FR FR7641A patent/FR1514910A/en not_active Expired
- 1963-01-18 GB GB2373/63A patent/GB1019162A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20130012473A1 (en) * | 2010-03-17 | 2013-01-10 | Ktb Tumorforschungsgesellschaft Mbh | Combined use of phospholipid and sulfate groups-carrying polysaccharides for inhibiting metastatic spread |
Also Published As
Publication number | Publication date |
---|---|
DE1174940B (en) | 1964-07-30 |
ES283985A1 (en) | 1963-03-16 |
FR1514910A (en) | 1968-03-01 |
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