GB1012245A - Quaternary ammonium compounds and method of preparing same - Google Patents

Quaternary ammonium compounds and method of preparing same

Info

Publication number
GB1012245A
GB1012245A GB2517763A GB2517763A GB1012245A GB 1012245 A GB1012245 A GB 1012245A GB 2517763 A GB2517763 A GB 2517763A GB 2517763 A GB2517763 A GB 2517763A GB 1012245 A GB1012245 A GB 1012245A
Authority
GB
United Kingdom
Prior art keywords
formula
alkyl
prepared
quaternary ammonium
alkenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2517763A
Inventor
Karl-Gustav Israelsson
Olle Martensson
Erling Nilsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Health AB
Original Assignee
Pharmacia AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia AB filed Critical Pharmacia AB
Priority to GB2517763A priority Critical patent/GB1012245A/en
Publication of GB1012245A publication Critical patent/GB1012245A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises non-toxic quaternary ammonium salts of compounds of the formula: <FORM:1012245/C2/1> wherein each of R1, R2 and R3 represents a phenyl or methyl substituted phenyl group, R4 represents a C2-4 alkylene group, each of R6 and R7 represents an alkyl, alkenyl or hydroxysubstituted alkyl, containing not more than 5 carbon atoms, or R6 and R7 are joined, possibly via an oxygen atom, to form, together with the nitrogen atom, a five or six-membered heterocyclic ring. The prepared compounds have the formula: <FORM:1012245/C2/2> wherein R1, R2, R3, R4, R6 and R7 are as defined above, R5 is alkyl, alkenyl or hydroxy-substituted alkyl, containing no more than 5 carbon atoms and X is chloro, bromo or another pharmacologically acceptable anion, and are prepared by reacting the parent amine with a quaternizing agent having the formula R5X. Amines of the Formula (I) are prepared by converting the appropriate triphenylmethane or the appropriate triphenylmethyl halide into its corresponding alkali metal salt, which is then reacted with the desired tertiary aminoalkyl halide. Reference has been directed by the Comptroller to Specification 875,955.
GB2517763A 1963-06-25 1963-06-25 Quaternary ammonium compounds and method of preparing same Expired GB1012245A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2517763A GB1012245A (en) 1963-06-25 1963-06-25 Quaternary ammonium compounds and method of preparing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2517763A GB1012245A (en) 1963-06-25 1963-06-25 Quaternary ammonium compounds and method of preparing same

Publications (1)

Publication Number Publication Date
GB1012245A true GB1012245A (en) 1965-12-08

Family

ID=10223487

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2517763A Expired GB1012245A (en) 1963-06-25 1963-06-25 Quaternary ammonium compounds and method of preparing same

Country Status (1)

Country Link
GB (1) GB1012245A (en)

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