GB1003349A - New piperazine derivatives - Google Patents
New piperazine derivativesInfo
- Publication number
- GB1003349A GB1003349A GB12995/64A GB1299564A GB1003349A GB 1003349 A GB1003349 A GB 1003349A GB 12995/64 A GB12995/64 A GB 12995/64A GB 1299564 A GB1299564 A GB 1299564A GB 1003349 A GB1003349 A GB 1003349A
- Authority
- GB
- United Kingdom
- Prior art keywords
- piperazine
- bis
- compound
- compounds
- pivaloyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000004885 piperazines Chemical class 0.000 title 1
- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- -1 methanesulphonyloxy Chemical group 0.000 abstract 3
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 2
- JVSFQJZRHXAUGT-UHFFFAOYSA-N 2,2-dimethylpropanoyl chloride Chemical compound CC(C)(C)C(Cl)=O JVSFQJZRHXAUGT-UHFFFAOYSA-N 0.000 abstract 1
- WLQZVZBUQRNSBR-UHFFFAOYSA-N 3-hydroxy-1-[4-(3-hydroxy-2,2-dimethylpropanoyl)piperazin-1-yl]-2,2-dimethylpropan-1-one Chemical compound OCC(C(=O)N1CCN(CC1)C(C(CO)(C)C)=O)(C)C WLQZVZBUQRNSBR-UHFFFAOYSA-N 0.000 abstract 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- 201000009030 Carcinoma Diseases 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 206010039491 Sarcoma Diseases 0.000 abstract 1
- NEPJLQJXAONGMZ-UHFFFAOYSA-N [3-[4-(3-acetyloxy-2,2-dimethylpropanoyl)piperazin-1-yl]-2,2-dimethyl-3-oxopropyl] acetate Chemical compound C(C)(=O)OCC(C(=O)N1CCN(CC1)C(C(COC(C)=O)(C)C)=O)(C)C NEPJLQJXAONGMZ-UHFFFAOYSA-N 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 239000011630 iodine Substances 0.000 abstract 1
- 208000032839 leukemia Diseases 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- CQLFBEKRDQMJLZ-UHFFFAOYSA-M silver acetate Chemical compound [Ag+].CC([O-])=O CQLFBEKRDQMJLZ-UHFFFAOYSA-M 0.000 abstract 1
- 229940071536 silver acetate Drugs 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 239000006188 syrup Substances 0.000 abstract 1
- 235000020357 syrup Nutrition 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR929571 | 1963-03-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1003349A true GB1003349A (en) | 1965-09-02 |
Family
ID=8800327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB12995/64A Expired GB1003349A (en) | 1963-03-28 | 1964-03-26 | New piperazine derivatives |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE645850A (enrdf_load_stackoverflow) |
| ES (1) | ES298096A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1003349A (enrdf_load_stackoverflow) |
| NL (1) | NL6403307A (enrdf_load_stackoverflow) |
| OA (1) | OA00115A (enrdf_load_stackoverflow) |
-
1964
- 1964-02-27 OA OA50017A patent/OA00115A/xx unknown
- 1964-03-26 NL NL6403307A patent/NL6403307A/xx unknown
- 1964-03-26 GB GB12995/64A patent/GB1003349A/en not_active Expired
- 1964-03-27 BE BE645850A patent/BE645850A/xx unknown
- 1964-03-28 ES ES0298096A patent/ES298096A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE645850A (enrdf_load_stackoverflow) | 1964-09-28 |
| OA00115A (fr) | 1966-01-15 |
| ES298096A1 (es) | 1964-06-01 |
| NL6403307A (enrdf_load_stackoverflow) | 1964-09-29 |
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