GB1003101A - New tetracycline salts and a process for the preparation thereof - Google Patents
New tetracycline salts and a process for the preparation thereofInfo
- Publication number
- GB1003101A GB1003101A GB299264A GB299264A GB1003101A GB 1003101 A GB1003101 A GB 1003101A GB 299264 A GB299264 A GB 299264A GB 299264 A GB299264 A GB 299264A GB 1003101 A GB1003101 A GB 1003101A
- Authority
- GB
- United Kingdom
- Prior art keywords
- tetracycline
- alkyl
- sulphate
- alkylsulphates
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 tetracycline salts Chemical class 0.000 title abstract 8
- 239000004098 Tetracycline Substances 0.000 title abstract 7
- 229960002180 tetracycline Drugs 0.000 title abstract 7
- 229930101283 tetracycline Natural products 0.000 title abstract 7
- 235000019364 tetracycline Nutrition 0.000 title abstract 7
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 4
- 150000003522 tetracyclines Chemical class 0.000 abstract 3
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 2
- 229910052783 alkali metal Inorganic materials 0.000 abstract 2
- 150000001340 alkali metals Chemical class 0.000 abstract 2
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- NWXMGUDVXFXRIG-WESIUVDSSA-N (4s,4as,5as,6s,12ar)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide Chemical compound C1=CC=C2[C@](O)(C)[C@H]3C[C@H]4[C@H](N(C)C)C(=O)C(C(N)=O)=C(O)[C@@]4(O)C(=O)C3=C(O)C2=C1O NWXMGUDVXFXRIG-WESIUVDSSA-N 0.000 abstract 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
- ZTHQBROSBNNGPU-UHFFFAOYSA-N Butyl hydrogen sulfate Chemical class CCCCOS(O)(=O)=O ZTHQBROSBNNGPU-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 150000001342 alkaline earth metals Chemical class 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 230000036765 blood level Effects 0.000 abstract 1
- 239000003729 cation exchange resin Substances 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 229940124531 pharmaceutical excipient Drugs 0.000 abstract 1
- GCLGEJMYGQKIIW-UHFFFAOYSA-H sodium hexametaphosphate Chemical compound [Na]OP1(=O)OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])O1 GCLGEJMYGQKIIW-UHFFFAOYSA-H 0.000 abstract 1
- 235000019982 sodium hexametaphosphate Nutrition 0.000 abstract 1
- 235000011149 sulphuric acid Nutrition 0.000 abstract 1
- 239000001117 sulphuric acid Substances 0.000 abstract 1
- 239000001577 tetrasodium phosphonato phosphate Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR924307A FR1356997A (fr) | 1963-02-11 | 1963-02-11 | Nouveaux dérivés de la tétracycline et procédé de préparation |
| FR933521A FR2857M (fr) | 1963-02-11 | 1963-05-03 | Nouveaux dérivés de la tétracycline utilisables en thérapeutique. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1003101A true GB1003101A (en) | 1965-09-02 |
Family
ID=26199758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB299264A Expired GB1003101A (en) | 1963-02-11 | 1964-01-23 | New tetracycline salts and a process for the preparation thereof |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE643588A (enrdf_load_stackoverflow) |
| ES (1) | ES295227A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1003101A (enrdf_load_stackoverflow) |
| LU (1) | LU45222A1 (enrdf_load_stackoverflow) |
| NL (1) | NL6401150A (enrdf_load_stackoverflow) |
-
1964
- 1964-01-11 ES ES295227A patent/ES295227A1/es not_active Expired
- 1964-01-15 LU LU45222D patent/LU45222A1/xx unknown
- 1964-01-23 GB GB299264A patent/GB1003101A/en not_active Expired
- 1964-02-10 BE BE643588D patent/BE643588A/xx unknown
- 1964-02-11 NL NL6401150A patent/NL6401150A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BE643588A (enrdf_load_stackoverflow) | 1964-08-10 |
| LU45222A1 (enrdf_load_stackoverflow) | 1965-07-15 |
| NL6401150A (enrdf_load_stackoverflow) | 1964-08-12 |
| ES295227A1 (es) | 1964-04-01 |
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