GB0912650D0 - Controlled release corticosteroid compositions and methods for the treatment of otic disorders - Google Patents

Controlled release corticosteroid compositions and methods for the treatment of otic disorders

Info

Publication number
GB0912650D0
GB0912650D0 GBGB0912650.9A GB0912650A GB0912650D0 GB 0912650 D0 GB0912650 D0 GB 0912650D0 GB 0912650 A GB0912650 A GB 0912650A GB 0912650 D0 GB0912650 D0 GB 0912650D0
Authority
GB
United Kingdom
Prior art keywords
treatment
methods
controlled release
otic disorders
corticosteroid compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GBGB0912650.9A
Other versions
GB2461186A (en
GB2461186B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Otonomy Inc
Original Assignee
University of California
Otonomy Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California, Otonomy Inc filed Critical University of California
Priority to GB0823378A priority Critical patent/GB2459910B/en
Publication of GB0912650D0 publication Critical patent/GB0912650D0/en
Publication of GB2461186A publication Critical patent/GB2461186A/en
Application granted granted Critical
Publication of GB2461186B publication Critical patent/GB2461186B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GB0912650A 2008-04-21 2008-12-22 Controlled release corticosteroid compositions and methods for the treatment of otic disorders Expired - Fee Related GB2461186B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB0823378A GB2459910B (en) 2008-04-21 2008-12-22 Controlled Release Corticosteroid Compositions and Methods for the Treatment of Otic Disorders

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4654308P 2008-04-21 2008-04-21
US12771308P 2008-05-14 2008-05-14
US8794008P 2008-08-11 2008-08-11
US9524808P 2008-09-08 2008-09-08
GB0823378A GB2459910B (en) 2008-04-21 2008-12-22 Controlled Release Corticosteroid Compositions and Methods for the Treatment of Otic Disorders

Publications (3)

Publication Number Publication Date
GB0912650D0 true GB0912650D0 (en) 2009-08-26
GB2461186A GB2461186A (en) 2009-12-30
GB2461186B GB2461186B (en) 2010-09-01

Family

ID=40344056

Family Applications (2)

Application Number Title Priority Date Filing Date
GB0912650A Expired - Fee Related GB2461186B (en) 2008-04-21 2008-12-22 Controlled release corticosteroid compositions and methods for the treatment of otic disorders
GB0823378A Expired - Fee Related GB2459910B (en) 2008-04-21 2008-12-22 Controlled Release Corticosteroid Compositions and Methods for the Treatment of Otic Disorders

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB0823378A Expired - Fee Related GB2459910B (en) 2008-04-21 2008-12-22 Controlled Release Corticosteroid Compositions and Methods for the Treatment of Otic Disorders

Country Status (1)

Country Link
GB (2) GB2461186B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2461962B (en) * 2008-07-25 2011-02-16 Otonomy Inc Slow release NMDA receptor antagonist for otic disorders
US8496957B2 (en) 2008-07-21 2013-07-30 Otonomy, Inc Controlled release auris sensory cell modulator compositions and methods for the treatment of otic disorders
WO2013130619A1 (en) * 2012-02-27 2013-09-06 O-Ray Pharma, Inc. Solid drug implants for intracochlear delivery of therapeutics for the treatment of otic disorders
JP2015527398A (en) 2012-09-07 2015-09-17 マサチューセッツ アイ アンド イヤー インファーマリー Hearing loss treatment
MX362187B (en) * 2013-03-15 2019-01-08 Oakwood Laboratories Sustained release microspheres and method of producing the same.
RU2761212C2 (en) * 2015-11-03 2021-12-06 Зоэтис Сервисиз Ллс Polymer composites obtained by sol-gel method, and their application
US20200214976A1 (en) * 2019-01-09 2020-07-09 Spiral Therapeutics, Inc. Self-gelling solutions for administration of therapeutics to the inner ear
CN110128467A (en) * 2019-05-07 2019-08-16 天津康巢生物医药股份有限公司 A kind of process of purification of glycerol phosphatidyl choline crude product and its obtained glycerolphosphocholine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003216379A1 (en) * 2002-02-22 2003-09-09 Control Delivery Systems, Inc. Method for treating otic disorders
WO2004039328A2 (en) * 2002-10-29 2004-05-13 Oregon Health & Science University Fludrocortisone treatment for hearing loss
US20060046970A1 (en) * 2004-08-31 2006-03-02 Insite Vision Incorporated Topical otic compositions and methods of topical treatment of prevention of otic infections

Also Published As

Publication number Publication date
GB2461186A (en) 2009-12-30
GB2459910A (en) 2009-11-11
GB2459910B (en) 2010-03-31
GB2461186B (en) 2010-09-01
GB0823378D0 (en) 2009-01-28

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20211222