GB0823378D0 - Controlled Release Corticosteroid Compositions and Methods for the Treatment of Otic Disorders - Google Patents

Controlled Release Corticosteroid Compositions and Methods for the Treatment of Otic Disorders

Info

Publication number
GB0823378D0
GB0823378D0 GBGB0823378.5A GB0823378A GB0823378D0 GB 0823378 D0 GB0823378 D0 GB 0823378D0 GB 0823378 A GB0823378 A GB 0823378A GB 0823378 D0 GB0823378 D0 GB 0823378D0
Authority
GB
United Kingdom
Prior art keywords
treatment
methods
controlled release
otic disorders
corticosteroid compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GBGB0823378.5A
Other versions
GB2459910B (en
GB2459910A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Otonomy Inc
Original Assignee
University of California
Otonomy Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California, Otonomy Inc filed Critical University of California
Priority to GB0912650A priority Critical patent/GB2461186B/en
Publication of GB0823378D0 publication Critical patent/GB0823378D0/en
Priority to PCT/US2009/003066 priority patent/WO2009139924A2/en
Priority to CN201310289183.9A priority patent/CN103417472B/en
Priority to KR1020137021389A priority patent/KR101534422B1/en
Priority to MX2010012397A priority patent/MX2010012397A/en
Priority to EP09747010.8A priority patent/EP2303227B1/en
Priority to CA2723458A priority patent/CA2723458C/en
Priority to AU2009246870A priority patent/AU2009246870B2/en
Priority to RU2010150863/15A priority patent/RU2469726C2/en
Priority to CN200980116869XA priority patent/CN102026623B/en
Priority to JP2011509498A priority patent/JP5551685B2/en
Priority to MYPI2010005337A priority patent/MY161021A/en
Priority to KR1020107026567A priority patent/KR101477329B1/en
Priority to BRPI0912482-9A priority patent/BRPI0912482A2/en
Priority to US12/466,310 priority patent/US8030297B2/en
Publication of GB2459910A publication Critical patent/GB2459910A/en
Application granted granted Critical
Publication of GB2459910B publication Critical patent/GB2459910B/en
Priority to US12/837,286 priority patent/US8546363B2/en
Priority to IL208806A priority patent/IL208806A/en
Priority to ZA2010/07482A priority patent/ZA201007482B/en
Priority to US13/190,323 priority patent/US8680082B2/en
Priority to US13/190,329 priority patent/US8680083B2/en
Priority to US13/190,330 priority patent/US8828980B2/en
Priority to US13/190,327 priority patent/US8658626B2/en
Priority to HK11110956.8A priority patent/HK1156533A1/en
Priority to RU2012139802/15A priority patent/RU2012139802A/en
Priority to JP2014049354A priority patent/JP6014069B2/en
Priority to US14/300,030 priority patent/US9744126B2/en
Priority to US14/795,819 priority patent/US9511020B2/en
Priority to IL244103A priority patent/IL244103A0/en
Priority to JP2016094870A priority patent/JP2016153423A/en
Priority to US15/612,701 priority patent/US20180110727A1/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
GB0823378A 2008-04-21 2008-12-22 Controlled Release Corticosteroid Compositions and Methods for the Treatment of Otic Disorders Expired - Fee Related GB2459910B (en)

Priority Applications (30)

Application Number Priority Date Filing Date Title
GB0912650A GB2461186B (en) 2008-04-21 2008-12-22 Controlled release corticosteroid compositions and methods for the treatment of otic disorders
RU2010150863/15A RU2469726C2 (en) 2008-05-14 2009-05-14 Corticosteroid-based composition with controlled release for treatment of ear diseases
JP2011509498A JP5551685B2 (en) 2008-05-14 2009-05-14 Controlled release corticosteroid compositions and methods of treating otic disorders
KR1020137021389A KR101534422B1 (en) 2008-05-14 2009-05-14 Controlled release corticosteroid compositions and methods for the treatment of otic disorders
MX2010012397A MX2010012397A (en) 2008-05-14 2009-05-14 Controlled release corticosteroid compositions and methods for the treatment of otic disorders.
EP09747010.8A EP2303227B1 (en) 2008-05-14 2009-05-14 Controlled release corticosteroid compositions and methods for the treatment of otic disorders
CA2723458A CA2723458C (en) 2008-05-14 2009-05-14 Controlled release corticosteroid compositions and methods for the treatment of otic disorders
AU2009246870A AU2009246870B2 (en) 2008-05-14 2009-05-14 Controlled release corticosteroid compositions and methods for the treatment of otic disorders
PCT/US2009/003066 WO2009139924A2 (en) 2008-05-14 2009-05-14 Controlled release corticosteroid compositions and methods for the treatment of otic disorders
CN200980116869XA CN102026623B (en) 2008-05-14 2009-05-14 Controlled release corticosteroid compositions and methods for the treatment of otic disorders
CN201310289183.9A CN103417472B (en) 2008-05-14 2009-05-14 For treating the control release corticosteroid composition and method of otic conditions
MYPI2010005337A MY161021A (en) 2008-05-14 2009-05-14 Controlled release corticosteroid and methods for the treatment of otic disorders
KR1020107026567A KR101477329B1 (en) 2008-05-14 2009-05-14 Controlled release corticosteroid compositions and methods for the treatment of otic disorders
BRPI0912482-9A BRPI0912482A2 (en) 2008-05-14 2009-05-14 controlled-release corticosteroid compositions and methods for the treatment of atrial disorders
US12/466,310 US8030297B2 (en) 2008-05-14 2009-05-14 Controlled release corticosteroid compositions and methods for the treatment of OTIC disorders
US12/837,286 US8546363B2 (en) 2008-05-14 2010-07-15 Controlled release corticosteroid compositions and methods for the treatment of otic disorders
IL208806A IL208806A (en) 2008-05-14 2010-10-19 Controlled release corticosteroid compositions and their use in the treatment of otic disorders
ZA2010/07482A ZA201007482B (en) 2008-05-14 2010-10-20 Controlled release corticosteriod compositions and methods for the treatment of otic disorders
US13/190,327 US8658626B2 (en) 2008-05-14 2011-07-25 Controlled release corticosteroid compositions and methods for the treatment of otic disorders
US13/190,323 US8680082B2 (en) 2008-05-14 2011-07-25 Controlled release corticosteroid compositions and methods for the treatment of otic disorders
US13/190,330 US8828980B2 (en) 2008-05-14 2011-07-25 Controlled release corticosteroid compositions and methods for the treatment of otic disorders
US13/190,329 US8680083B2 (en) 2008-05-14 2011-07-25 Controlled release corticosteroid compositions and methods for the treatment of otic disorders
HK11110956.8A HK1156533A1 (en) 2008-05-14 2011-10-14 Controlled release corticosteroid compositions and methods for the treatment of otic disorders
RU2012139802/15A RU2012139802A (en) 2008-05-14 2012-09-18 COMPOSITIONS WITH CONTROLLED RELEASE ON THE BASIS OF CORTICOSTEROIDS FOR THE TREATMENT OF EAR DISEASES
JP2014049354A JP6014069B2 (en) 2008-05-14 2014-03-12 Controlled release corticosteroid compositions and methods of treating otic disorders
US14/300,030 US9744126B2 (en) 2008-05-14 2014-06-09 Controlled release corticosteroid compositions and methods for the treatment of otic disorders
US14/795,819 US9511020B2 (en) 2008-05-14 2015-07-09 Controlled release corticosteroid compositions and methods for the treatment of otic disorders
IL244103A IL244103A0 (en) 2008-05-14 2016-02-14 Controlled release corticosteroid compositions and their use in the treatment of otic disorders
JP2016094870A JP2016153423A (en) 2008-05-14 2016-05-10 Controlled release corticosteroid compositions and methods for treatment of otic disorders
US15/612,701 US20180110727A1 (en) 2008-05-14 2017-06-02 Controlled release corticosteroid compositions and methods for the treatment of otic disorders

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4654308P 2008-04-21 2008-04-21
US12771308P 2008-05-14 2008-05-14
US8794008P 2008-08-11 2008-08-11
US9524808P 2008-09-08 2008-09-08
GB0912650A GB2461186B (en) 2008-04-21 2008-12-22 Controlled release corticosteroid compositions and methods for the treatment of otic disorders

Publications (3)

Publication Number Publication Date
GB0823378D0 true GB0823378D0 (en) 2009-01-28
GB2459910A GB2459910A (en) 2009-11-11
GB2459910B GB2459910B (en) 2010-03-31

Family

ID=40344056

Family Applications (2)

Application Number Title Priority Date Filing Date
GB0823378A Expired - Fee Related GB2459910B (en) 2008-04-21 2008-12-22 Controlled Release Corticosteroid Compositions and Methods for the Treatment of Otic Disorders
GB0912650A Expired - Fee Related GB2461186B (en) 2008-04-21 2008-12-22 Controlled release corticosteroid compositions and methods for the treatment of otic disorders

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB0912650A Expired - Fee Related GB2461186B (en) 2008-04-21 2008-12-22 Controlled release corticosteroid compositions and methods for the treatment of otic disorders

Country Status (1)

Country Link
GB (2) GB2459910B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108601723A (en) * 2015-11-03 2018-09-28 硕腾服务有限责任公司 Collosol-gel polymer composite material and application thereof

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2461962B (en) * 2008-07-25 2011-02-16 Otonomy Inc Slow release NMDA receptor antagonist for otic disorders
US8496957B2 (en) 2008-07-21 2013-07-30 Otonomy, Inc Controlled release auris sensory cell modulator compositions and methods for the treatment of otic disorders
WO2013130619A1 (en) 2012-02-27 2013-09-06 O-Ray Pharma, Inc. Solid drug implants for intracochlear delivery of therapeutics for the treatment of otic disorders
WO2014039781A1 (en) 2012-09-07 2014-03-13 Massachusetts Eye & Ear Infirmary Treating hearing loss
CN105705141B (en) * 2013-03-15 2018-12-28 奥克伍德实验室有限责任公司 Sustained-release micro-spheres and preparation method thereof
US20200214976A1 (en) * 2019-01-09 2020-07-09 Spiral Therapeutics, Inc. Self-gelling solutions for administration of therapeutics to the inner ear
CN110128467A (en) * 2019-05-07 2019-08-16 天津康巢生物医药股份有限公司 A kind of process of purification of glycerol phosphatidyl choline crude product and its obtained glycerolphosphocholine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003071986A2 (en) * 2002-02-22 2003-09-04 Control Delivery Systems, Inc. Method for treating otic disorders
US20060013858A1 (en) * 2002-10-29 2006-01-19 Trune Dennis R Fludrocortisone treatment for hearing loss
US20060046970A1 (en) * 2004-08-31 2006-03-02 Insite Vision Incorporated Topical otic compositions and methods of topical treatment of prevention of otic infections

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108601723A (en) * 2015-11-03 2018-09-28 硕腾服务有限责任公司 Collosol-gel polymer composite material and application thereof
CN108601723B (en) * 2015-11-03 2022-05-17 硕腾服务有限责任公司 Sol-gel polymer composite and use thereof

Also Published As

Publication number Publication date
GB0912650D0 (en) 2009-08-26
GB2461186B (en) 2010-09-01
GB2459910B (en) 2010-03-31
GB2461186A (en) 2009-12-30
GB2459910A (en) 2009-11-11

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20201222