GB0614754D0 - C-8 linked pyrrolo[2,1-c][1,4]benzodiazepine-acridone/acridine hybrids - Google Patents

C-8 linked pyrrolo[2,1-c][1,4]benzodiazepine-acridone/acridine hybrids

Info

Publication number
GB0614754D0
GB0614754D0 GBGB0614754.0A GB0614754A GB0614754D0 GB 0614754 D0 GB0614754 D0 GB 0614754D0 GB 0614754 A GB0614754 A GB 0614754A GB 0614754 D0 GB0614754 D0 GB 0614754D0
Authority
GB
United Kingdom
Prior art keywords
acridone
benzodiazepine
acridine
hybrids
linked pyrrolo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GBGB0614754.0A
Other versions
GB2424884A (en
GB2424884B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Council of Scientific and Industrial Research CSIR
Original Assignee
Council of Scientific and Industrial Research CSIR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Council of Scientific and Industrial Research CSIR filed Critical Council of Scientific and Industrial Research CSIR
Publication of GB0614754D0 publication Critical patent/GB0614754D0/en
Publication of GB2424884A publication Critical patent/GB2424884A/en
Application granted granted Critical
Publication of GB2424884B publication Critical patent/GB2424884B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB0614754A 2003-12-31 2003-12-31 C-8 linked pyrrolo[2,1-c][1,4]benzodiazepine-acridone/acridine hybrids Expired - Fee Related GB2424884B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IN2003/000464 WO2005063760A1 (en) 2003-12-31 2003-12-31 C-8 LINKED PYRROLO[2,1-c][1,4]BENZODIAZEPINE-ACRIDONE/ACRIDINE HYBRIDS

Publications (3)

Publication Number Publication Date
GB0614754D0 true GB0614754D0 (en) 2006-09-06
GB2424884A GB2424884A (en) 2006-10-11
GB2424884B GB2424884B (en) 2008-06-11

Family

ID=34717581

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0614754A Expired - Fee Related GB2424884B (en) 2003-12-31 2003-12-31 C-8 linked pyrrolo[2,1-c][1,4]benzodiazepine-acridone/acridine hybrids

Country Status (4)

Country Link
JP (1) JP4718328B2 (en)
AU (1) AU2003300720A1 (en)
GB (1) GB2424884B (en)
WO (1) WO2005063760A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5149193B2 (en) * 2005-11-10 2013-02-20 カウンスィル オブ サイエンティフィック アンド インダストリアル リサーチ Novel pyrrolo [2,1-c] [1,4] benzodiazepine hybrids and methods for their preparation
ATE543826T1 (en) * 2007-08-01 2012-02-15 Council Scient Ind Res PYRROLOÄ2,1-CUÄ1,4ÜBENZODIAZEPINE GLYCOSIDE-PRODRU S SUITABLE AS SELECTIVE ANTITUMOR AGENTS
IL301637B2 (en) 2017-09-29 2024-10-01 Daiichi Sankyo Co Ltd Antibody-pyrrolobenzodiazepine derivative conjugate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201084A (en) * 1982-06-25 1985-10-11 New Zealand Dev Finance 4-carboxamidoacridine derivatives and pharmaceutical compositions containing such
GB9621795D0 (en) * 1996-10-18 1996-12-11 Xenova Ltd Pharmaceutical compounds
ES2244210T3 (en) * 1998-08-27 2005-12-01 Spirogen Limited PIRROLOBENZODIAZEPINAS.

Also Published As

Publication number Publication date
AU2003300720A1 (en) 2005-07-21
JP2007528344A (en) 2007-10-11
JP4718328B2 (en) 2011-07-06
GB2424884A (en) 2006-10-11
GB2424884B (en) 2008-06-11
WO2005063760A1 (en) 2005-07-14

Similar Documents

Publication Publication Date Title
GB0325143D0 (en) Datacasting
PL1699795T3 (en) Substituted 8'-pyri(mi)dinyl-dihydrospiro-[cycloalklymine]-pyrimido[1,2a]pyrimidin-6-one derivatives
EP1653969A4 (en) Pyrrolo 1,2-b pyridazine derivatives
IL170680A0 (en) 8 - SUBSTITUTED - 6,7,8,9 -TETRAHYDROPYRIMIDO [1,2-a] PYRIMIDIN - 4 - ONE DERIVATIVES
IL172592A0 (en) Pyrazolopyrimidines
ZA200509884B (en) 6-Cyclylmethyl- and 6-alkylmethyl-substituted pyrazolopyrimidines
IL172098A0 (en) Triazolopyrimidines
GB0209896D0 (en) Conjugate
ZA200507192B (en) Substituted 8-perfluoroalkyl-6,7,8,9-tetrahydropyrimido [1,2-A] pyrimidin-4-one derivatives
ZA200510276B (en) Triazolopyrimidines
GB2446080B (en) A novel Pyrrolo [2,1-C][1,4] benzodiazepine hybrid and a process for the preparation thereof
ZA200610587B (en) 1-Heterocyclyl-1,5-dihydro-pyrido[3,2-b]indol-2-ones
GB0318324D0 (en) No title
GB2454629B (en) Pyrrolo[2, 1-c][1, 4]benzodiazepine hybrids and a process for the preparation thereof
AU2003901897A0 (en) Conjugate
PL372989A1 (en) Triazolopyrimidines
EP1628919A4 (en) Improved solar still
AU2003226725A8 (en) Pyrazolopyrimidine derivatives
GB2424884B (en) C-8 linked pyrrolo[2,1-c][1,4]benzodiazepine-acridone/acridine hybrids
GB2424883B (en) Process for preparing pyrrolo[2, 1-c] [1,4] benzodiazepine hybrids
GB0221778D0 (en) Conjugate
ZA200510374B (en) Pyrazolopyrimidines
GB2425309B (en) C2-fluoro pyrrolo[2,1-c][1,4]benzodiazepine dimers
EP1596119A4 (en) Fitting
GB0504282D0 (en) No title

Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20171231