GB0213498D0 - Deoxyhypusine-synthase inhibitors pharmaceuticals comprising said inhibitors and uses thereof - Google Patents

Deoxyhypusine-synthase inhibitors pharmaceuticals comprising said inhibitors and uses thereof

Info

Publication number
GB0213498D0
GB0213498D0 GBGB0213498.9A GB0213498A GB0213498D0 GB 0213498 D0 GB0213498 D0 GB 0213498D0 GB 0213498 A GB0213498 A GB 0213498A GB 0213498 D0 GB0213498 D0 GB 0213498D0
Authority
GB
United Kingdom
Prior art keywords
inhibitors
deoxyhypusine
pharmaceuticals
synthase
synthase inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GBGB0213498.9A
Other versions
GB2389581A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VIAXXEL BIOTECH GmbH
Original Assignee
VIAXXEL BIOTECH GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by VIAXXEL BIOTECH GmbH filed Critical VIAXXEL BIOTECH GmbH
Priority to GB0213498A priority Critical patent/GB2389581A/en
Publication of GB0213498D0 publication Critical patent/GB0213498D0/en
Priority to AU2003240743A priority patent/AU2003240743A1/en
Priority to PCT/EP2003/005854 priority patent/WO2003106433A1/en
Publication of GB2389581A publication Critical patent/GB2389581A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/04—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
GB0213498A 2002-06-12 2002-06-12 Hydrogenated pyrimidines and their use as inhibitors of deoxyhypusine-synthase or hypusination of eIF-5A Withdrawn GB2389581A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GB0213498A GB2389581A (en) 2002-06-12 2002-06-12 Hydrogenated pyrimidines and their use as inhibitors of deoxyhypusine-synthase or hypusination of eIF-5A
AU2003240743A AU2003240743A1 (en) 2002-06-12 2003-06-04 Deoxyhypusine-synthase inhibitors, pharmaceuticals comprising said inhibitors and uses thereof
PCT/EP2003/005854 WO2003106433A1 (en) 2002-06-12 2003-06-04 Deoxyhypusine-synthase inhibitors, pharmaceuticals comprising said inhibitors and uses thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0213498A GB2389581A (en) 2002-06-12 2002-06-12 Hydrogenated pyrimidines and their use as inhibitors of deoxyhypusine-synthase or hypusination of eIF-5A

Publications (2)

Publication Number Publication Date
GB0213498D0 true GB0213498D0 (en) 2002-07-24
GB2389581A GB2389581A (en) 2003-12-17

Family

ID=9938447

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0213498A Withdrawn GB2389581A (en) 2002-06-12 2002-06-12 Hydrogenated pyrimidines and their use as inhibitors of deoxyhypusine-synthase or hypusination of eIF-5A

Country Status (3)

Country Link
AU (1) AU2003240743A1 (en)
GB (1) GB2389581A (en)
WO (1) WO2003106433A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2962906A1 (en) 2010-07-20 2012-01-27 Univ Nice Sophia Antipolis USE OF INHIBITORS OF HYPUSINYLATION OF eIF5A TO TREAT ISCHEMIC AND HYPOXIC DISEASES

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4138563A (en) * 1978-01-05 1979-02-06 American Cyanamid Company 2-Acylamidoethyl-2-tetrahydropyrimidines
US4427802A (en) * 1981-07-27 1984-01-24 Hexcel Corporation Heterocyclic multifunctional amine adducts and curable compositions containing the same
US5091576A (en) * 1986-12-02 1992-02-25 University Of Florida Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives
WO1992005190A1 (en) * 1990-09-17 1992-04-02 The Children's Medical Center Corporation Deoxyhypusyl hydroxylase inhibitors
US5849587A (en) * 1995-06-09 1998-12-15 Cornell Research Foundation, Inc. Method of inhibiting viral replication in eukaryotic cells and of inducing apoptosis of virally-infected cells
JP2000503999A (en) * 1996-02-02 2000-04-04 フアルマシア・エ・アツプジヨン・エツセ・ピー・アー Distamycin derivatives, their preparation, and their use as antitumor and antiviral agents
AU6621600A (en) * 1999-08-04 2001-03-05 Millennium Pharmaceuticals, Inc. Melanocortin-4 receptor binding compounds and methods of use thereof

Also Published As

Publication number Publication date
AU2003240743A1 (en) 2003-12-31
WO2003106433A1 (en) 2003-12-24
GB2389581A (en) 2003-12-17

Similar Documents

Publication Publication Date Title
EP1539941A4 (en) Adzymes and uses thereof
HK1079427A1 (en) Acylated heteroaryl-condensed cycloalkenylamines and their use as pharmaceuticals
IL166491A0 (en) Acylated arylcycloalkylamines and their use as pharmaceuticals
PL375447A1 (en) Protein kinase inhibitors and uses thereof
AU2003282478A8 (en) Discount-instrument methods and systems
HK1087699A1 (en) Gyrase inhibitors and uses thereof
IL166377A0 (en) Vrgfr-2 and vgefr-3 inhibitory and anthranylamidpyrimidines
PL378135A1 (en) 2-cyanopyrrolopyrimidines and pharmaceutical uses thereof
EG25097A (en) Piprazinyl and diazapanyl benzamides and benzthioamides.
PL374598A1 (en) Caspase inhibitors and uses thereof
EP1538907A4 (en) Inhibitors of ftsz and uses thereof
IL163868A0 (en) Hermiasterlin derivatives and uses thereof
AU2003232848A8 (en) Phenylaminopyrimidines and their use as rho-kinase inhibitors
PL374581A1 (en) Diaminothiazoles and use thereof as cdk4 inhibitors
SI1551805T1 (en) Substituted gamma-phenyl-delta-lactams and uses related thereto
AU2002230036A8 (en) Glucosamine-polyacrylate inter-polymer complex and applications thereof
AU2003211520A1 (en) Lfa-1 inhibitors and use thereof
IL165112A0 (en) Variant integrinpolypeptides and thereof
AU2003251513A8 (en) Rsk inhibitors and therapeutic uses thereof
AU2003231827A8 (en) Pseudo-tissues and uses thereof
AU2003302173A8 (en) Spirotetrathiocarbamates and spirooxothiocarbamates
AU2003267790A8 (en) Lipase inhibitors and uses thereof
GB0213498D0 (en) Deoxyhypusine-synthase inhibitors pharmaceuticals comprising said inhibitors and uses thereof
GB0220776D0 (en) FOXP2 and uses thereof
EP1487547A4 (en) Physical interaction means and related uses thereof

Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)