FR3093645B1 - Puce microfluidique pour attirer et détruire un élément biologique spécifique - Google Patents

Puce microfluidique pour attirer et détruire un élément biologique spécifique Download PDF

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Publication number
FR3093645B1
FR3093645B1 FR1902686A FR1902686A FR3093645B1 FR 3093645 B1 FR3093645 B1 FR 3093645B1 FR 1902686 A FR1902686 A FR 1902686A FR 1902686 A FR1902686 A FR 1902686A FR 3093645 B1 FR3093645 B1 FR 3093645B1
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FR
France
Prior art keywords
biological element
reservoir
destroy
microfluidic chip
attract
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1902686A
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English (en)
Other versions
FR3093645A1 (fr
Inventor
Benoît Charlot
Jean-Marie Ramirez
Sébastien Meance
Xavier Garric
Coline Pinese
Isabelle Guiraud
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Universite de Montpellier I
Ecole Nationale Superieure de Chimie de Montpellier ENSCM
Universite de Montpellier
Original Assignee
Centre National de la Recherche Scientifique CNRS
Universite de Montpellier I
Ecole Nationale Superieure de Chimie de Montpellier ENSCM
Universite de Montpellier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR1902686A priority Critical patent/FR3093645B1/fr
Application filed by Centre National de la Recherche Scientifique CNRS, Universite de Montpellier I, Ecole Nationale Superieure de Chimie de Montpellier ENSCM, Universite de Montpellier filed Critical Centre National de la Recherche Scientifique CNRS
Priority to EP20726185.0A priority patent/EP3938033A1/fr
Priority to PCT/FR2020/050527 priority patent/WO2020188198A1/fr
Priority to CN202080021574.0A priority patent/CN113677394A/zh
Priority to AU2020243245A priority patent/AU2020243245A1/en
Priority to US17/435,075 priority patent/US20220133392A1/en
Priority to JP2021555532A priority patent/JP2022525454A/ja
Priority to CA3128578A priority patent/CA3128578A1/fr
Priority to BR112021017925A priority patent/BR112021017925A2/pt
Publication of FR3093645A1 publication Critical patent/FR3093645A1/fr
Application granted granted Critical
Publication of FR3093645B1 publication Critical patent/FR3093645B1/fr
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Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1808—Epidermal growth factor [EGF] urogastrone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1841—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A61K38/1866—Vascular endothelial growth factor [VEGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/195—Chemokines, e.g. RANTES
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00017—Electrical control of surgical instruments
    • A61B2017/00221—Electrical control of surgical instruments with wireless transmission of data, e.g. by infrared radiation or radiowaves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00613—Irreversible electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1405—Electrodes having a specific shape
    • A61B2018/1407—Loop

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Vascular Medicine (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Plasma & Fusion (AREA)
  • Otolaryngology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Micromachines (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

La présente invention concerne une puce microfluidique pour attirer et détruire un élément biologique spécifique, ladite puce comprenant : - un réservoir (1) constitué d’une matrice comprenant un composé chimioattractant capable d’attirer l’élément biologique - au moins un réseau de microcanaux (2) disposé entre le réservoir (1) et le milieu extérieur (3) de la puce et permettant de laisser passer le composé chimioattractant vers ledit milieu et de laisser passer l’élément biologique présent dans ledit milieu en direction du réservoir (1) - au moins une électrode (4) disposée entre le réservoir (1) et le réseau de microcanaux (2), ladite électrode (4) étant apte à générer un champ électrique de façon à détruire l’élément biologique lors de son passage vers le réservoir (1). Figure pour l’abrégé: Fig. 1
FR1902686A 2019-03-15 2019-03-15 Puce microfluidique pour attirer et détruire un élément biologique spécifique Active FR3093645B1 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FR1902686A FR3093645B1 (fr) 2019-03-15 2019-03-15 Puce microfluidique pour attirer et détruire un élément biologique spécifique
PCT/FR2020/050527 WO2020188198A1 (fr) 2019-03-15 2020-03-12 Puce microfluidique pour attirer et detruire un element biologique specifique
CN202080021574.0A CN113677394A (zh) 2019-03-15 2020-03-12 用于吸引和破坏特定生物元件的微流控芯片
AU2020243245A AU2020243245A1 (en) 2019-03-15 2020-03-12 Microfluidic chip for attracting and destroying a specific biological element
EP20726185.0A EP3938033A1 (fr) 2019-03-15 2020-03-12 Puce microfluidique pour attirer et detruire un element biologique specifique
US17/435,075 US20220133392A1 (en) 2019-03-15 2020-03-12 Microfluidic chip for attracting and destroying a specific biological element
JP2021555532A JP2022525454A (ja) 2019-03-15 2020-03-12 特定の生物学的成分を誘引して破壊するためのマイクロ流体チップ
CA3128578A CA3128578A1 (fr) 2019-03-15 2020-03-12 Puce microfluidique pour attirer et detruire un element biologique specifique
BR112021017925A BR112021017925A2 (pt) 2019-03-15 2020-03-12 Chip microfluídico para atrair e destruir um elemento biológico específico

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1902686A FR3093645B1 (fr) 2019-03-15 2019-03-15 Puce microfluidique pour attirer et détruire un élément biologique spécifique
FR1902686 2019-03-15

Publications (2)

Publication Number Publication Date
FR3093645A1 FR3093645A1 (fr) 2020-09-18
FR3093645B1 true FR3093645B1 (fr) 2021-04-02

Family

ID=68072508

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1902686A Active FR3093645B1 (fr) 2019-03-15 2019-03-15 Puce microfluidique pour attirer et détruire un élément biologique spécifique

Country Status (9)

Country Link
US (1) US20220133392A1 (fr)
EP (1) EP3938033A1 (fr)
JP (1) JP2022525454A (fr)
CN (1) CN113677394A (fr)
AU (1) AU2020243245A1 (fr)
BR (1) BR112021017925A2 (fr)
CA (1) CA3128578A1 (fr)
FR (1) FR3093645B1 (fr)
WO (1) WO2020188198A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3122830A1 (fr) * 2021-05-17 2022-11-18 Université De Montpellier (Um) Puce microfluidique pour attirer et piéger un élément biologique spécifique

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2183024T (pt) * 2007-08-14 2019-08-01 Novocure Ltd Tratando parasitas com campos elétricos
US20120322685A1 (en) * 2010-01-25 2012-12-20 Condeelis John S Device for collecting and analyzing migratory tumor cells
US10953400B2 (en) 2016-10-26 2021-03-23 Iowa State University Research Foundation, Inc. High-throughput selective capture of biological cells by dielectrophoresis at a bipolar electrode array
EP3538215A1 (fr) 2016-11-14 2019-09-18 The Charles Stark Draper Laboratory, Inc. Destruction sélective de cellules par résonance électromagnétique

Also Published As

Publication number Publication date
US20220133392A1 (en) 2022-05-05
BR112021017925A2 (pt) 2021-11-16
WO2020188198A1 (fr) 2020-09-24
EP3938033A1 (fr) 2022-01-19
FR3093645A1 (fr) 2020-09-18
JP2022525454A (ja) 2022-05-16
CA3128578A1 (fr) 2020-09-24
AU2020243245A1 (en) 2021-09-23
CN113677394A (zh) 2021-11-19

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