FR3044676B1 - Dendrimeres photosensibilisateurs biphotoniques, procede de fabrication et utilisations - Google Patents

Dendrimeres photosensibilisateurs biphotoniques, procede de fabrication et utilisations

Info

Publication number
FR3044676B1
FR3044676B1 FR1561898A FR1561898A FR3044676B1 FR 3044676 B1 FR3044676 B1 FR 3044676B1 FR 1561898 A FR1561898 A FR 1561898A FR 1561898 A FR1561898 A FR 1561898A FR 3044676 B1 FR3044676 B1 FR 3044676B1
Authority
FR
France
Prior art keywords
biphotonic
dendrimers
photosensitizer
manufacture
photosensitizer dendrimers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1561898A
Other languages
English (en)
Other versions
FR3044676A1 (fr
Inventor
Aude Sourdon
Olivier Mongin
Mireille Blanchard-Desce
Magali Gary-Bobo
Marcel Garcia
Marie Maynadier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bordeaux Inp
Centre National de la Recherche Scientifique CNRS
Universite de Rennes 1
Universite de Montpellier I
Universite de Montpellier
Universite de Bordeaux
Original Assignee
Bordeaux Inp
Centre National de la Recherche Scientifique CNRS
Universite de Rennes 1
Universite de Montpellier I
Universite de Montpellier
Universite de Bordeaux
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bordeaux Inp, Centre National de la Recherche Scientifique CNRS, Universite de Rennes 1, Universite de Montpellier I, Universite de Montpellier, Universite de Bordeaux filed Critical Bordeaux Inp
Priority to FR1561898A priority Critical patent/FR3044676B1/fr
Priority to PCT/FR2016/053198 priority patent/WO2017093698A1/fr
Publication of FR3044676A1 publication Critical patent/FR3044676A1/fr
Application granted granted Critical
Publication of FR3044676B1 publication Critical patent/FR3044676B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/06—Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/008—Two-Photon or Multi-Photon PDT, e.g. with upconverting dyes or photosensitisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/08—Hydrogen atoms or radicals containing only hydrogen and carbon atoms
    • C07D333/10—Thiophene
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids R2P(=O)(OH); Thiophosphinic acids, i.e. R2P(=X)(XH) (X = S, Se)
    • C07F9/36—Amides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/65812—Cyclic phosphazenes [P=N-]n, n>=3
    • C07F9/65814—Cyclic phosphazenes [P=N-]n, n>=3 n = 3 or 4
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002—Dendritic macromolecules
    • C08G83/003—Dendrimers
FR1561898A 2015-12-04 2015-12-04 Dendrimeres photosensibilisateurs biphotoniques, procede de fabrication et utilisations Expired - Fee Related FR3044676B1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR1561898A FR3044676B1 (fr) 2015-12-04 2015-12-04 Dendrimeres photosensibilisateurs biphotoniques, procede de fabrication et utilisations
PCT/FR2016/053198 WO2017093698A1 (fr) 2015-12-04 2016-12-02 Dendrimeres photosensibilisateurs biphotoniques, procede de fabrication et utilisations

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1561898A FR3044676B1 (fr) 2015-12-04 2015-12-04 Dendrimeres photosensibilisateurs biphotoniques, procede de fabrication et utilisations

Publications (2)

Publication Number Publication Date
FR3044676A1 FR3044676A1 (fr) 2017-06-09
FR3044676B1 true FR3044676B1 (fr) 2017-11-24

Family

ID=55542823

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1561898A Expired - Fee Related FR3044676B1 (fr) 2015-12-04 2015-12-04 Dendrimeres photosensibilisateurs biphotoniques, procede de fabrication et utilisations

Country Status (2)

Country Link
FR (1) FR3044676B1 (fr)
WO (1) WO2017093698A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111423443A (zh) * 2020-04-03 2020-07-17 广州科锐特生物科技有限公司 一种4-氨基-7-碘吡咯并[2,1-f][1,2,4]三嗪的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2896251B1 (fr) * 2006-01-13 2008-04-11 Univ Rennes 1 Etablissement Pu Composes fluorescents dendrimeriques et utilisation de tels composes dans le cadre de procedes ou dispositifs multiphotoniques.
EP2513083B1 (fr) * 2009-12-15 2016-04-06 Centre National de la Recherche Scientifique (CNRS) Photosensibilateurs biophotoniques, nanoparticules les contenant et leur utilisation en tant que médicaments

Also Published As

Publication number Publication date
FR3044676A1 (fr) 2017-06-09
WO2017093698A1 (fr) 2017-06-08

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